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Adiposity distribution and risks of 12 obesity-related cancers: a Mendelian randomization analysis.

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Title: Adiposity distribution and risks of 12 obesity-related cancers: a Mendelian randomization analysis.
Authors: Hazelwood E; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Goudswaard LJ; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Lee MA; Nutrition and Metabolism Branch, International Agency for Research on Cancer (IARC- WHO), Lyon, France., Vabistsevits M; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.; Clinical and Biomedical Sciences, University of Exeter, Exeter, United Kingdom., Pournaras DJ; Department of Upper GI and Bariatric/Metabolic Surgery, North Bristol NHS Trust, Southmead Hospital, Bristol, United Kingdom., Brenner H; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Buchanan DD; Colorectal Oncogenomics Group, Department of Clinical Pathology, Melbourne Medical School, The University of Melbourne, Parkville, Australia.; University of Melbourne Centre for Cancer Research, The University of Melbourne, Parkville, Australia.; Genomic Medicine and Family Cancer Clinic, The Royal Melbourne Hospital, Parkville, Victoria, Australia., Gruber SB; Department of Medical Oncology and Therapeutics Research and Center for Precision Medicine, City of Hope National Medical Center, Duarte, CA, United States., Gsur A; Center for Cancer Research, Medical University of Vienna, Vienna, Austria., Li L; Department of Family Medicine, University of Virginia, Charlottesville, VA, United States., Vodickova L; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Prague, Czech Republic.; Faculty of Medicine and Biomedical Center in Pilsen, Charles University, Pilsen, Czech Republic., Grant RC; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada., Samadder NJ; Division of Gastroenterology, Mayo Clinic, Phoenix, AZ, United States., Timpson NJ; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Gunter MJ; Nutrition and Metabolism Branch, International Agency for Research on Cancer (IARC- WHO), Lyon, France.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom., Schuster-Böckler B; Ludwig Institute for Cancer Research, University of Oxford, Oxford, United Kingdom., Yarmolinsky J; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom., Richardson TG; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Freisling H; Nutrition and Metabolism Branch, International Agency for Research on Cancer (IARC- WHO), Lyon, France., Murphy N; Nutrition and Metabolism Branch, International Agency for Research on Cancer (IARC- WHO), Lyon, France., Vincent EE; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Source: Journal of the National Cancer Institute [J Natl Cancer Inst] 2025 Dec 01; Vol. 117 (12), pp. 2621-2642.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 7503089 Publication Model: Print Cited Medium: Internet ISSN: 1460-2105 (Electronic) Linking ISSN: 00278874 NLM ISO Abbreviation: J Natl Cancer Inst Subsets: MEDLINE
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  Data: Adiposity distribution and risks of 12 obesity-related cancers: a Mendelian randomization analysis.
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  Data: <searchLink fieldCode="AU" term="%22Hazelwood+E%22">Hazelwood E</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Goudswaard+LJ%22">Goudswaard LJ</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lee+MA%22">Lee MA</searchLink>; Nutrition and Metabolism Branch, International Agency for Research on Cancer (IARC- WHO), Lyon, France.<br /><searchLink fieldCode="AU" term="%22Vabistsevits+M%22">Vabistsevits M</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.; Clinical and Biomedical Sciences, University of Exeter, Exeter, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pournaras+DJ%22">Pournaras DJ</searchLink>; Department of Upper GI and Bariatric/Metabolic Surgery, North Bristol NHS Trust, Southmead Hospital, Bristol, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Brenner+H%22">Brenner H</searchLink>; Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Buchanan+DD%22">Buchanan DD</searchLink>; Colorectal Oncogenomics Group, Department of Clinical Pathology, Melbourne Medical School, The University of Melbourne, Parkville, Australia.; University of Melbourne Centre for Cancer Research, The University of Melbourne, Parkville, Australia.; Genomic Medicine and Family Cancer Clinic, The Royal Melbourne Hospital, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Gruber+SB%22">Gruber SB</searchLink>; Department of Medical Oncology and Therapeutics Research and Center for Precision Medicine, City of Hope National Medical Center, Duarte, CA, United States.<br /><searchLink fieldCode="AU" term="%22Gsur+A%22">Gsur A</searchLink>; Center for Cancer Research, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Department of Family Medicine, University of Virginia, Charlottesville, VA, United States.<br /><searchLink fieldCode="AU" term="%22Vodickova+L%22">Vodickova L</searchLink>; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Prague, Czech Republic.; Faculty of Medicine and Biomedical Center in Pilsen, Charles University, Pilsen, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Grant+RC%22">Grant RC</searchLink>; Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Samadder+NJ%22">Samadder NJ</searchLink>; Division of Gastroenterology, Mayo Clinic, Phoenix, AZ, United States.<br /><searchLink fieldCode="AU" term="%22Timpson+NJ%22">Timpson NJ</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gunter+MJ%22">Gunter MJ</searchLink>; Nutrition and Metabolism Branch, International Agency for Research on Cancer (IARC- WHO), Lyon, France.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Schuster-Böckler+B%22">Schuster-Böckler B</searchLink>; Ludwig Institute for Cancer Research, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Yarmolinsky+J%22">Yarmolinsky J</searchLink>; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Richardson+TG%22">Richardson TG</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Freisling+H%22">Freisling H</searchLink>; Nutrition and Metabolism Branch, International Agency for Research on Cancer (IARC- WHO), Lyon, France.<br /><searchLink fieldCode="AU" term="%22Murphy+N%22">Murphy N</searchLink>; Nutrition and Metabolism Branch, International Agency for Research on Cancer (IARC- WHO), Lyon, France.<br /><searchLink fieldCode="AU" term="%22Vincent+EE%22">Vincent EE</searchLink>; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.; Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
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