Development and clinical validation of a novel protein biomarkers-based algorithm for risk prediction and diagnosis of advanced liver fibrosis: a multi-centre study.
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| Title: | Development and clinical validation of a novel protein biomarkers-based algorithm for risk prediction and diagnosis of advanced liver fibrosis: a multi-centre study. |
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| Authors: | Cheung CY; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China., Wan P; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China., Wan H; Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Foshan City, Guangdong, China., Xu C; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China., Jia X; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China., Fong CH; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China., Lui DT; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China., Song E; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China., Chen X; Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Foshan City, Guangdong, China., Chow WS; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China., Woo YC; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China., Tan KC; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China., Seto WK; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China., Wang C; Department of Metabolic and Bariatric Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China., Shen J; Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Foshan City, Guangdong, China. Electronic address: sjiesy@smu.edu.cn., Lam KS; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China. Electronic address: ksllam@hku.hk., Lee CH; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China. Electronic address: pchlee@hku.hk., Xu A; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China. Electronic address: amxu@hku.hk. |
| Source: | Journal of advanced research [J Adv Res] 2026 Jun; Vol. 84, pp. 871-881. Date of Electronic Publication: 2025 Sep 22. |
| Publication Type: | Journal Article; Multicenter Study; Validation Study; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Cairo University, production and hosting by Elsevier B. V Country of Publication: Egypt NLM ID: 101546952 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2090-1224 (Electronic) Linking ISSN: 20901224 NLM ISO Abbreviation: J Adv Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40992726 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Development and clinical validation of a novel protein biomarkers-based algorithm for risk prediction and diagnosis of advanced liver fibrosis: a multi-centre study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Cheung+CY%22">Cheung CY</searchLink>; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Wan+P%22">Wan P</searchLink>; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Wan+H%22">Wan H</searchLink>; Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Foshan City, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Xu+C%22">Xu C</searchLink>; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Jia+X%22">Jia X</searchLink>; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Fong+CH%22">Fong CH</searchLink>; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Lui+DT%22">Lui DT</searchLink>; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Song+E%22">Song E</searchLink>; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Foshan City, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Chow+WS%22">Chow WS</searchLink>; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Woo+YC%22">Woo YC</searchLink>; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Tan+KC%22">Tan KC</searchLink>; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Seto+WK%22">Seto WK</searchLink>; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Department of Metabolic and Bariatric Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Shen+J%22">Shen J</searchLink>; Department of Endocrinology and Metabolism, Shunde Hospital, Southern Medical University (The First People's Hospital of Shunde, Foshan), Foshan City, Guangdong, China. Electronic address: sjiesy@smu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Lam+KS%22">Lam KS</searchLink>; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China. Electronic address: ksllam@hku.hk.<br /><searchLink fieldCode="AU" term="%22Lee+CH%22">Lee CH</searchLink>; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China. Electronic address: pchlee@hku.hk.<br /><searchLink fieldCode="AU" term="%22Xu+A%22">Xu A</searchLink>; State Key Laboratory of Pharmaceutical Biotechnology, University of Hong Kong, Hong Kong, China; Department of Medicine, School of Clinical Medicine, University of Hong Kong, Hong Kong, China; Guangdong-Hong Kong Joint Institute for Metabolic Medicine, University of Hong Kong, Hong Kong, China. Electronic address: amxu@hku.hk. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101546952%22">Journal of advanced research</searchLink> [J Adv Res] 2026 Jun; Vol. 84, pp. 871-881. <i>Date of Electronic Publication: </i>2025 Sep 22. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Multicenter Study; Validation Study; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cairo+University%2C+production+and+hosting+by+Elsevier+B%2E+V%22">Cairo University, production and hosting by Elsevier B. V </searchLink><i>Country of Publication: </i>Egypt <i>NLM ID: </i>101546952 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2090-1224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220901224%22">20901224 </searchLink><i>NLM ISO Abbreviation: </i>J Adv Res <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40992726 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.jare.2025.09.033 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 871 Titles: – TitleFull: Development and clinical validation of a novel protein biomarkers-based algorithm for risk prediction and diagnosis of advanced liver fibrosis: a multi-centre study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Cheung CY – PersonEntity: Name: NameFull: Wan P – PersonEntity: Name: NameFull: Wan H – PersonEntity: Name: NameFull: Xu C – PersonEntity: Name: NameFull: Jia X – PersonEntity: Name: NameFull: Fong CH – PersonEntity: Name: NameFull: Lui DT – PersonEntity: Name: NameFull: Song E – PersonEntity: Name: NameFull: Chen X – PersonEntity: Name: NameFull: Chow WS – PersonEntity: Name: NameFull: Woo YC – PersonEntity: Name: NameFull: Tan KC – PersonEntity: Name: NameFull: Seto WK – PersonEntity: Name: NameFull: Wang C – PersonEntity: Name: NameFull: Shen J – PersonEntity: Name: NameFull: Lam KS – PersonEntity: Name: NameFull: Lee CH – PersonEntity: Name: NameFull: Xu A IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2026 Jun Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2090-1224 Numbering: – Type: volume Value: 84 Titles: – TitleFull: Journal of advanced research Type: main |
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