View in EDS HTML Full Text PDF Full Text

An integrated multi-omic natural history study of human development, sexual dimorphism, and the effects of trisomy 21.

Saved in:
Bibliographic Details
Title: An integrated multi-omic natural history study of human development, sexual dimorphism, and the effects of trisomy 21.
Authors: Eduthan NP; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA., Donovan MG; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA., Araya P; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA., Rachubinski AL; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.; Department of Pediatrics, Section of Developmental Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA., Sullivan KD; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.; Department of Pediatrics, Section of Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA., Galbraith MD; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA. matthew.galbraith@cuanschutz.edu.; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA. matthew.galbraith@cuanschutz.edu., Espinosa JM; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA. joaquin.espinosa@cuanschutz.edu.; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA. joaquin.espinosa@cuanschutz.edu.
Source: Nature communications [Nat Commun] 2025 Sep 24; Vol. 16 (1), pp. 8346. Date of Electronic Publication: 2025 Sep 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40993118
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: An integrated multi-omic natural history study of human development, sexual dimorphism, and the effects of trisomy 21.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Eduthan+NP%22">Eduthan NP</searchLink>; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Donovan+MG%22">Donovan MG</searchLink>; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Araya+P%22">Araya P</searchLink>; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Rachubinski+AL%22">Rachubinski AL</searchLink>; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.; Department of Pediatrics, Section of Developmental Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Sullivan+KD%22">Sullivan KD</searchLink>; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.; Department of Pediatrics, Section of Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA.<br /><searchLink fieldCode="AU" term="%22Galbraith+MD%22">Galbraith MD</searchLink>; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA. matthew.galbraith@cuanschutz.edu.; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA. matthew.galbraith@cuanschutz.edu.<br /><searchLink fieldCode="AU" term="%22Espinosa+JM%22">Espinosa JM</searchLink>; Linda Crnic Institute for Down Syndrome, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA. joaquin.espinosa@cuanschutz.edu.; Department of Pharmacology, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA. joaquin.espinosa@cuanschutz.edu.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Sep 24; Vol. 16 (1), pp. 8346. <i>Date of Electronic Publication: </i>2025 Sep 24.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101528555 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-1723 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220411723%22">20411723 </searchLink><i>NLM ISO Abbreviation: </i>Nat Commun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40993118
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41467-025-63862-9
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 8346
    Titles:
      – TitleFull: An integrated multi-omic natural history study of human development, sexual dimorphism, and the effects of trisomy 21.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Eduthan NP
      – PersonEntity:
          Name:
            NameFull: Donovan MG
      – PersonEntity:
          Name:
            NameFull: Araya P
      – PersonEntity:
          Name:
            NameFull: Rachubinski AL
      – PersonEntity:
          Name:
            NameFull: Sullivan KD
      – PersonEntity:
          Name:
            NameFull: Galbraith MD
      – PersonEntity:
          Name:
            NameFull: Espinosa JM
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 24
              M: 09
              Text: 2025 Sep 24
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 16
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1