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PlyNJ3: a three-domain endolysin with broad-spectrum anti-streptococcal activity and synergistic efficacy against multidrug-resistant Streptococcus suis.

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Title: PlyNJ3: a three-domain endolysin with broad-spectrum anti-streptococcal activity and synergistic efficacy against multidrug-resistant Streptococcus suis.
Authors: Zhao J; MOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, Nanjing Agricultural University, Nanjing, 210095, China.; Laboratory of Gastrointestinal Microbiology, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, 210095, China., Wang J; MOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, Nanjing Agricultural University, Nanjing, 210095, China., Han P; MOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, Nanjing Agricultural University, Nanjing, 210095, China., Yin C; Ningxia Hui Autonomous Region Center for Animal Disease Control and Prevention, Yinchuan, 750002, China., Gu S; Nanjing Animal Husbandry and Veterinary Station, Nanjing, 210012, China., Ji H; MOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, Nanjing Agricultural University, Nanjing, 210095, China., Wang X; MOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, Nanjing Agricultural University, Nanjing, 210095, China., Wang L; MOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, Nanjing Agricultural University, Nanjing, 210095, China., Huang J; MOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, Nanjing Agricultural University, Nanjing, 210095, China. jhuang@njau.edu.cn.
Source: BMC veterinary research [BMC Vet Res] 2025 Sep 24; Vol. 21 (1), pp. 540. Date of Electronic Publication: 2025 Sep 24.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101249759 Publication Model: Electronic Cited Medium: Internet ISSN: 1746-6148 (Electronic) Linking ISSN: 17466148 NLM ISO Abbreviation: BMC Vet Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PlyNJ3: a three-domain endolysin with broad-spectrum anti-streptococcal activity and synergistic efficacy against multidrug-resistant Streptococcus suis.
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  Data: <searchLink fieldCode="AU" term="%22Zhao+J%22">Zhao J</searchLink>; MOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, Nanjing Agricultural University, Nanjing, 210095, China.; Laboratory of Gastrointestinal Microbiology, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, 210095, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; MOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, Nanjing Agricultural University, Nanjing, 210095, China.<br /><searchLink fieldCode="AU" term="%22Han+P%22">Han P</searchLink>; MOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, Nanjing Agricultural University, Nanjing, 210095, China.<br /><searchLink fieldCode="AU" term="%22Yin+C%22">Yin C</searchLink>; Ningxia Hui Autonomous Region Center for Animal Disease Control and Prevention, Yinchuan, 750002, China.<br /><searchLink fieldCode="AU" term="%22Gu+S%22">Gu S</searchLink>; Nanjing Animal Husbandry and Veterinary Station, Nanjing, 210012, China.<br /><searchLink fieldCode="AU" term="%22Ji+H%22">Ji H</searchLink>; MOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, Nanjing Agricultural University, Nanjing, 210095, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; MOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, Nanjing Agricultural University, Nanjing, 210095, China.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; MOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, Nanjing Agricultural University, Nanjing, 210095, China.<br /><searchLink fieldCode="AU" term="%22Huang+J%22">Huang J</searchLink>; MOE Joint International Research Laboratory of Animal Health and Food Safety, Risk Assessment Center of Veterinary Drug Residue and Antimicrobial Resistance, Center for Veterinary Drug Research and Evaluation, Nanjing Agricultural University, Nanjing, 210095, China. jhuang@njau.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101249759%22">BMC veterinary research</searchLink> [BMC Vet Res] 2025 Sep 24; Vol. 21 (1), pp. 540. <i>Date of Electronic Publication: </i>2025 Sep 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101249759 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1746-6148 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217466148%22">17466148 </searchLink><i>NLM ISO Abbreviation: </i>BMC Vet Res <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12917-025-04975-7
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              M: 09
              Text: 2025 Sep 24
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