Personalized treatment in HPV+ oropharynx cancer using genomic adjusted radiation dose.

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Title: Personalized treatment in HPV+ oropharynx cancer using genomic adjusted radiation dose.
Authors: Ho E; Department of Genomic Medicine, Cleveland Clinic Research, Cleveland, Ohio, USA.; School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA., De Cecco L; Integrated Biology of Rare Tumors, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Eschrich SA; Department of Biostatistics and Biomedical Informatics, Moffitt Cancer Center, Tampa, Florida, USA., Cavalieri S; Head and Neck Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy., Sedor G; Radiation Oncology Department, NewYork-Presbyterian Hospital/Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA., Hoebers F; Department of Radiation Oncology (Maastro), GROW School for Oncology and Reproduction, Maastricht University Medical Centre+, Maastricht, Netherlands., Brakenhoff RH; Amsterdam UMC, Vrije Universiteit Amsterdam, Otolaryngology/Head and Neck Surgery, Cancer Center Amsterdam, Amsterdam, Netherlands., Scheckenbach K; Department of Otolaryngology, Medical Faculty, Heinrich Heine University Dusseldorf, Dusseldorf, Germany., Poli T; Unit of Maxillofacial Surgery, Department of Medicine and Surgery, University of Parma-University Hospital of Parma, Parma, Italy., Yang K; Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa, USA., Scarborough JA; Department of Genomic Medicine, Cleveland Clinic Research, Cleveland, Ohio, USA.; School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA., Nellore S; Department of Genomic Medicine, Cleveland Clinic Research, Cleveland, Ohio, USA.; School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA., Campbell S; Department of Radiation Oncology, and., Woody N; Department of Radiation Oncology, and., Chan T; Department of Radiation Oncology, and.; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, Ohio, USA., Miller J; Department of Radiation Oncology, and.; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, Ohio, USA., Silver N; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, Ohio, USA., Koyfman S; Department of Radiation Oncology, and., Bates J; Department of Radiation Oncology, Emory University, Atlanta, Georgia, USA., Caudell JJ; Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida, USA., Kattan MW; Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland Ohio, USA., Licitra L; Head and Neck Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy., Torres-Roca JF; Department of Biostatistics and Biomedical Informatics, Moffitt Cancer Center, Tampa, Florida, USA.; Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida, USA., Scott JG; Department of Genomic Medicine, Cleveland Clinic Research, Cleveland, Ohio, USA.; School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Radiation Oncology, and.; Departments of Physics and Biology, Case Western Reserve University, Cleveland, Ohio, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2025 Oct 01; Vol. 135 (19). Date of Electronic Publication: 2025 Oct 01 (Print Publication: 2025).
Publication Type: Journal Article; Multicenter Study; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Personalized treatment in HPV+ oropharynx cancer using genomic adjusted radiation dose.
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  Data: <searchLink fieldCode="AU" term="%22Ho+E%22">Ho E</searchLink>; Department of Genomic Medicine, Cleveland Clinic Research, Cleveland, Ohio, USA.; School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22De+Cecco+L%22">De Cecco L</searchLink>; Integrated Biology of Rare Tumors, Experimental Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Eschrich+SA%22">Eschrich SA</searchLink>; Department of Biostatistics and Biomedical Informatics, Moffitt Cancer Center, Tampa, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Cavalieri+S%22">Cavalieri S</searchLink>; Head and Neck Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sedor+G%22">Sedor G</searchLink>; Radiation Oncology Department, NewYork-Presbyterian Hospital/Columbia University Vagelos College of Physicians and Surgeons, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Hoebers+F%22">Hoebers F</searchLink>; Department of Radiation Oncology (Maastro), GROW School for Oncology and Reproduction, Maastricht University Medical Centre+, Maastricht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Brakenhoff+RH%22">Brakenhoff RH</searchLink>; Amsterdam UMC, Vrije Universiteit Amsterdam, Otolaryngology/Head and Neck Surgery, Cancer Center Amsterdam, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Scheckenbach+K%22">Scheckenbach K</searchLink>; Department of Otolaryngology, Medical Faculty, Heinrich Heine University Dusseldorf, Dusseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Poli+T%22">Poli T</searchLink>; Unit of Maxillofacial Surgery, Department of Medicine and Surgery, University of Parma-University Hospital of Parma, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Yang+K%22">Yang K</searchLink>; Department of Radiation Oncology, Holden Comprehensive Cancer Center, University of Iowa, Iowa City, Iowa, USA.<br /><searchLink fieldCode="AU" term="%22Scarborough+JA%22">Scarborough JA</searchLink>; Department of Genomic Medicine, Cleveland Clinic Research, Cleveland, Ohio, USA.; School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Nellore+S%22">Nellore S</searchLink>; Department of Genomic Medicine, Cleveland Clinic Research, Cleveland, Ohio, USA.; School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Campbell+S%22">Campbell S</searchLink>; Department of Radiation Oncology, and.<br /><searchLink fieldCode="AU" term="%22Woody+N%22">Woody N</searchLink>; Department of Radiation Oncology, and.<br /><searchLink fieldCode="AU" term="%22Chan+T%22">Chan T</searchLink>; Department of Radiation Oncology, and.; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Miller+J%22">Miller J</searchLink>; Department of Radiation Oncology, and.; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Silver+N%22">Silver N</searchLink>; Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Koyfman+S%22">Koyfman S</searchLink>; Department of Radiation Oncology, and.<br /><searchLink fieldCode="AU" term="%22Bates+J%22">Bates J</searchLink>; Department of Radiation Oncology, Emory University, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Caudell+JJ%22">Caudell JJ</searchLink>; Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Kattan+MW%22">Kattan MW</searchLink>; Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Licitra+L%22">Licitra L</searchLink>; Head and Neck Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.; Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Torres-Roca+JF%22">Torres-Roca JF</searchLink>; Department of Biostatistics and Biomedical Informatics, Moffitt Cancer Center, Tampa, Florida, USA.; Department of Radiation Oncology, Moffitt Cancer Center, Tampa, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Scott+JG%22">Scott JG</searchLink>; Department of Genomic Medicine, Cleveland Clinic Research, Cleveland, Ohio, USA.; School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Radiation Oncology, and.; Departments of Physics and Biology, Case Western Reserve University, Cleveland, Ohio, USA.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2025 Oct 01; Vol. 135 (19). <i>Date of Electronic Publication: </i>2025 Oct 01 (<i>Print Publication: </i>2025).
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  Data: Journal Article; Multicenter Study; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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