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Extended molecular profiling in mesenchymal tumors: a consensus paper from the Italian Sarcoma Group.

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Title: Extended molecular profiling in mesenchymal tumors: a consensus paper from the Italian Sarcoma Group.
Authors: D'Ambrosio L; Department of Oncology, University of Torino, Regione Gonzole 10, Orbassano, TO 10043, Italy; AOU San Luigi Gonzaga, Regione Gonzole 10, Orbassano, TO 10043, Italy. Electronic address: lorenzo.dambrosio@unito.it., Sbaraglia M; Department of Integrated Diagnostics, Azienda Ospedale-Università Padova, Via A.Gabelli, 61, Padova 35128, Italy; Department of Medicine, University of Padova School of Medicine, Via A.Gabelli, 61, Padova 35128, Italy., Merlini A; Department of Oncology, University of Torino, Regione Gonzole 10, Orbassano, TO 10043, Italy; AOU San Luigi Gonzaga, Regione Gonzole 10, Orbassano, TO 10043, Italy. Electronic address: alessandra.merlini@unito.it., Rabino M; Department of Oncology, University of Torino, Regione Gonzole 10, Orbassano, TO 10043, Italy; AOU San Luigi Gonzaga, Regione Gonzole 10, Orbassano, TO 10043, Italy., Grignani G; Division of Medical Oncology, Candiolo Cancer Institute, FPO - IRCCS, Strada Provinciale 142, Km 3.95, Candiolo, TO 10060, Italy., Appolloni V; Italian Sarcoma Group, Via Vanzetti 5, Milano 20133, Italy., Badalamenti G; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), Section of Medical Oncology, University of Palermo, Via Liborio Giuffrè 5, Palermo 90127, Italy., Baldi GG; Department of Oncology, Hospital of Prato, Azienda USL Toscana Centro, Via Suor Niccolina Infermiera 20/22, Prato 59100, Italy., Bellan E; Department of Integrated Diagnostics, Azienda Ospedale-Università Padova, Via A.Gabelli, 61, Padova 35128, Italy; Department of Medicine, University of Padova School of Medicine, Via A.Gabelli, 61, Padova 35128, Italy., Benelli M; University of Firenze, Piazza San Marco 4, Firenze 50121, Italy., Bertuzzi AF; Medical Oncology Department, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, MI 20089, Italy., Biagini R; Oncology Orthopeadic Unit; IRCCS Regina Elena National Cancer Institute, Via Chianesi 53, Rome 00144, Italy., Bianchi G; Unit of 3rd Orthopaedic and Traumatologic Clinic Prevalently Oncologic, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy IRCCS Istituto Ortopedico Rizzoli, Via G.C. Pupilli 1, Bologna 40136, Italy., Boglione A; Oncologia 2, Ospedale San Giovanni Bosco, piazza Donatori di Sangue, 3, Torino 10154, Italy., Brunello A; Medical Oncology 1 Unit, Department of Medical Oncology, Istituto Oncologico Veneto IOV IRCCS, Via Gattamelata, 64, Padova 35128, Italy., Campanacci DA; Department of Surgery, Azienda Ospedaliera Universitaria Careggi, Largo Brambilla 3, Firenze 50134, Italy; Department of Health Sciences, University of Firenze, Viale Pieraccini 6, Firenze 50139, Italy., Cananzi F; Sarcoma, Melanoma and Rare Tumors Surgery Unit, IRCCS Humanitas Research Hospital, Rozzano, Via Manzoni 56, Rozzano, MI 20089, Italy; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, MI 20072, Italy., Casali PG; Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy; University of Milano, Via Festa del Perdono 7, Milano 20122, Italy., Casini B; Department of Pathology, IRCCS Regina Elena National Cancer Institute, Via Chianesi 53, Rome 00144, Italy., Cesari M; Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy., Chiusole B; Medical Oncology 1 Unit, Department of Medical Oncology, Istituto Oncologico Veneto IOV IRCCS, Via Gattamelata, 64, Padova 35128, Italy., Cristalli C; Laboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, Via G.C. Pupilli 1, Bologna 40136, Italy., De Vita A; Preclinic and Osteoncology Unit, Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Via Piero Maroncelli 40, Meldola 47014, Italy., Di Blasi E; Pathology, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy., Fagioli F; Pediatric Onco-Hematology, Ospedale Infantile Regina Margherita & Departmento of Sciences of Public Health and Pediatrics, Univeristy of Torino, Piazza Polonia 94, Torino 10126, Italy., Fausti V; Terapie cellulari avanzate e tumori rari, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Via Piero Maroncelli 40, Meldola 47014, Italy., Ferraresi V; Department of Sarcomas and Rare Tumors Departmental Unit, IRCCS Regina Elena National Cancer Institute, Via Chianesi 53, Rome 00144, Italy., Frezza AM; Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy., Fumagalli E; Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy., Gambarotti M; Department of Pathology, IRCCS Istituto Ortopedico Rizzoli, Via G.C. Pupilli 1, Bologna 40136, Italy., Giani C; Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy; University of Milano, Via Festa del Perdono 7, Milano 20122, Italy., Gronchi A; Department of Surgery, Sarcoma Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy., Grassi M; Department of Medical Oncology, IRCCS Ospedale Policlinico San Martino, Largo R. Benzi, 10, Genova 16132, Italy., Ibrahim T; Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy., Ivanescu A; Associazione EHE Italia, Concorezzo, MB 20863, Italy., Ignazzi G; Italian Sarcoma Group, Via Vanzetti 5, Milano 20133, Italy., Incorvaia L; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), Section of Medical Oncology, University of Palermo, Via Liborio Giuffrè 5, Palermo 90127, Italy., Linari A; Pathology Unit, Città della Salute e della Scienza di Torino, Corso Bramante 88, Torino 10126, Italy., Luksch R; Pediatric Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy., Marrari A; Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy., Mazzocca A; Department of Medical Oncology, Policlinico Universitario Campus Bio-Medico and Università Campus Bio-Medico, via Álvaro del Portillo 200, Roma 00128, Italy., Milano GM; Division of Pediatric Hematology and Oncology, Bambino Gesù Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, Roma 00165, Italy., Morosi C; Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy., Nannini M; Department of Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Via Giuseppe Massarenti, 9, Bologna 40138, Italy., Navarria P; Department of Radiation Therapy, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, MI 20089, Italy., Palassini E; Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy., Palmerini E; Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; Sylvester Comprehensive Cancer Center, University of Miami, 1475 NW 12th Ave, Miami, FL 33136, USA; Miller School of Medicine, University of Miami, 1475 NW 12th Ave, Miami, FL 33136, USA., Paloschi F; Fondazione Italiana GIST ETS, Via G Venezian 1, Milano 20133, Italy., Pantaleo MA; Department of Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Via Giuseppe Massarenti, 9, Bologna 40138, Italy., Pasquali S; Department of Surgery, Sarcoma Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy; Molecular Pharmacology, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Giovanni Antonio Amadeo 42, Milano 20133, Italy., Pavese V; Department of Oncology, University of Torino, Regione Gonzole 10, Orbassano, TO 10043, Italy; AOU San Luigi Gonzaga, Regione Gonzole 10, Orbassano, TO 10043, Italy., Pozzo E; Department of Radiation Therapy, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, MI 20089, Italy., Quagliuolo V; Sarcoma, Melanoma and Rare Tumors Surgery Unit, IRCCS Humanitas Research Hospital, Rozzano, Via Manzoni 56, Rozzano, MI 20089, Italy., Quirino M; Medical Oncology, Policlinico Gemelli, Largo Agostino Gemelli 8, Roma 00136, Italy., Sanfilippo R; Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy., Santoro F; Pathology Unit, Città della Salute e della Scienza di Torino, Corso Bramante 88, Torino 10126, Italy., Scotlandi K; Laboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, Via G.C. Pupilli 1, Bologna 40136, Italy., Serra M; Department of Pathology, IRCCS Istituto Ortopedico Rizzoli, Via G.C. Pupilli 1, Bologna 40136, Italy., Setola E; Department of Medical Oncology, IRCCS Istituto Europeo Oncologia, Via Giuseppe Ripamonti 435, Milano 20141, Italy., Strippoli S; Rare Tumors and Melanoma Unit, I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, Bari 70124, Italy., Tafuto S; Department of Sarcomas and Rare Tumors, Istituto Nazionale Tumori - IRCCS, Fondazione 'G.Pascale', Via Mariano Semmola 52, Napoli 80131, Italy., Tirtei E; Pediatric Onco-Hematology, Ospedale Infantile Regina Margherita & Departmento of Sciences of Public Health and Pediatrics, Univeristy of Torino, Piazza Polonia 94, Torino 10126, Italy., Vanni S; Preclinic and Osteoncology Unit, Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Via Piero Maroncelli 40, Meldola 47014, Italy., Vincenzi B; Department of Medical Oncology, Policlinico Universitario Campus Bio-Medico and Università Campus Bio-Medico, via Álvaro del Portillo 200, Roma 00128, Italy., Maestro R; Unit of Oncogenetics and Functional Oncogenomics, IRCCS Centro di Riferimento Oncologico di Aviano, , Via Franco Gallini 2, Aviano, PN 33081, Italy., Dei Tos AP; Department of Integrated Diagnostics, Azienda Ospedale-Università Padova, Via A.Gabelli, 61, Padova 35128, Italy; Department of Medicine, University of Padova School of Medicine, Via A.Gabelli, 61, Padova 35128, Italy., Stacchiotti S; Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy.
Source: Critical reviews in oncology/hematology [Crit Rev Oncol Hematol] 2025 Dec; Vol. 216, pp. 104960. Date of Electronic Publication: 2025 Sep 23.
Publication Type: Journal Article; Review; Consensus Statement
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Netherlands NLM ID: 8916049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0461 (Electronic) Linking ISSN: 10408428 NLM ISO Abbreviation: Crit Rev Oncol Hematol Subsets: MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: Extended molecular profiling in mesenchymal tumors: a consensus paper from the Italian Sarcoma Group.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22D'Ambrosio+L%22">D'Ambrosio L</searchLink>; Department of Oncology, University of Torino, Regione Gonzole 10, Orbassano, TO 10043, Italy; AOU San Luigi Gonzaga, Regione Gonzole 10, Orbassano, TO 10043, Italy. Electronic address: lorenzo.dambrosio@unito.it.<br /><searchLink fieldCode="AU" term="%22Sbaraglia+M%22">Sbaraglia M</searchLink>; Department of Integrated Diagnostics, Azienda Ospedale-Università Padova, Via A.Gabelli, 61, Padova 35128, Italy; Department of Medicine, University of Padova School of Medicine, Via A.Gabelli, 61, Padova 35128, Italy.<br /><searchLink fieldCode="AU" term="%22Merlini+A%22">Merlini A</searchLink>; Department of Oncology, University of Torino, Regione Gonzole 10, Orbassano, TO 10043, Italy; AOU San Luigi Gonzaga, Regione Gonzole 10, Orbassano, TO 10043, Italy. Electronic address: alessandra.merlini@unito.it.<br /><searchLink fieldCode="AU" term="%22Rabino+M%22">Rabino M</searchLink>; Department of Oncology, University of Torino, Regione Gonzole 10, Orbassano, TO 10043, Italy; AOU San Luigi Gonzaga, Regione Gonzole 10, Orbassano, TO 10043, Italy.<br /><searchLink fieldCode="AU" term="%22Grignani+G%22">Grignani G</searchLink>; Division of Medical Oncology, Candiolo Cancer Institute, FPO - IRCCS, Strada Provinciale 142, Km 3.95, Candiolo, TO 10060, Italy.<br /><searchLink fieldCode="AU" term="%22Appolloni+V%22">Appolloni V</searchLink>; Italian Sarcoma Group, Via Vanzetti 5, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Badalamenti+G%22">Badalamenti G</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), Section of Medical Oncology, University of Palermo, Via Liborio Giuffrè 5, Palermo 90127, Italy.<br /><searchLink fieldCode="AU" term="%22Baldi+GG%22">Baldi GG</searchLink>; Department of Oncology, Hospital of Prato, Azienda USL Toscana Centro, Via Suor Niccolina Infermiera 20/22, Prato 59100, Italy.<br /><searchLink fieldCode="AU" term="%22Bellan+E%22">Bellan E</searchLink>; Department of Integrated Diagnostics, Azienda Ospedale-Università Padova, Via A.Gabelli, 61, Padova 35128, Italy; Department of Medicine, University of Padova School of Medicine, Via A.Gabelli, 61, Padova 35128, Italy.<br /><searchLink fieldCode="AU" term="%22Benelli+M%22">Benelli M</searchLink>; University of Firenze, Piazza San Marco 4, Firenze 50121, Italy.<br /><searchLink fieldCode="AU" term="%22Bertuzzi+AF%22">Bertuzzi AF</searchLink>; Medical Oncology Department, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, MI 20089, Italy.<br /><searchLink fieldCode="AU" term="%22Biagini+R%22">Biagini R</searchLink>; Oncology Orthopeadic Unit; IRCCS Regina Elena National Cancer Institute, Via Chianesi 53, Rome 00144, Italy.<br /><searchLink fieldCode="AU" term="%22Bianchi+G%22">Bianchi G</searchLink>; Unit of 3rd Orthopaedic and Traumatologic Clinic Prevalently Oncologic, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy IRCCS Istituto Ortopedico Rizzoli, Via G.C. Pupilli 1, Bologna 40136, Italy.<br /><searchLink fieldCode="AU" term="%22Boglione+A%22">Boglione A</searchLink>; Oncologia 2, Ospedale San Giovanni Bosco, piazza Donatori di Sangue, 3, Torino 10154, Italy.<br /><searchLink fieldCode="AU" term="%22Brunello+A%22">Brunello A</searchLink>; Medical Oncology 1 Unit, Department of Medical Oncology, Istituto Oncologico Veneto IOV IRCCS, Via Gattamelata, 64, Padova 35128, Italy.<br /><searchLink fieldCode="AU" term="%22Campanacci+DA%22">Campanacci DA</searchLink>; Department of Surgery, Azienda Ospedaliera Universitaria Careggi, Largo Brambilla 3, Firenze 50134, Italy; Department of Health Sciences, University of Firenze, Viale Pieraccini 6, Firenze 50139, Italy.<br /><searchLink fieldCode="AU" term="%22Cananzi+F%22">Cananzi F</searchLink>; Sarcoma, Melanoma and Rare Tumors Surgery Unit, IRCCS Humanitas Research Hospital, Rozzano, Via Manzoni 56, Rozzano, MI 20089, Italy; Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, Pieve Emanuele, MI 20072, Italy.<br /><searchLink fieldCode="AU" term="%22Casali+PG%22">Casali PG</searchLink>; Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy; University of Milano, Via Festa del Perdono 7, Milano 20122, Italy.<br /><searchLink fieldCode="AU" term="%22Casini+B%22">Casini B</searchLink>; Department of Pathology, IRCCS Regina Elena National Cancer Institute, Via Chianesi 53, Rome 00144, Italy.<br /><searchLink fieldCode="AU" term="%22Cesari+M%22">Cesari M</searchLink>; Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Chiusole+B%22">Chiusole B</searchLink>; Medical Oncology 1 Unit, Department of Medical Oncology, Istituto Oncologico Veneto IOV IRCCS, Via Gattamelata, 64, Padova 35128, Italy.<br /><searchLink fieldCode="AU" term="%22Cristalli+C%22">Cristalli C</searchLink>; Laboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, Via G.C. Pupilli 1, Bologna 40136, Italy.<br /><searchLink fieldCode="AU" term="%22De+Vita+A%22">De Vita A</searchLink>; Preclinic and Osteoncology Unit, Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Via Piero Maroncelli 40, Meldola 47014, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Blasi+E%22">Di Blasi E</searchLink>; Pathology, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Fagioli+F%22">Fagioli F</searchLink>; Pediatric Onco-Hematology, Ospedale Infantile Regina Margherita & Departmento of Sciences of Public Health and Pediatrics, Univeristy of Torino, Piazza Polonia 94, Torino 10126, Italy.<br /><searchLink fieldCode="AU" term="%22Fausti+V%22">Fausti V</searchLink>; Terapie cellulari avanzate e tumori rari, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Via Piero Maroncelli 40, Meldola 47014, Italy.<br /><searchLink fieldCode="AU" term="%22Ferraresi+V%22">Ferraresi V</searchLink>; Department of Sarcomas and Rare Tumors Departmental Unit, IRCCS Regina Elena National Cancer Institute, Via Chianesi 53, Rome 00144, Italy.<br /><searchLink fieldCode="AU" term="%22Frezza+AM%22">Frezza AM</searchLink>; Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Fumagalli+E%22">Fumagalli E</searchLink>; Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Gambarotti+M%22">Gambarotti M</searchLink>; Department of Pathology, IRCCS Istituto Ortopedico Rizzoli, Via G.C. Pupilli 1, Bologna 40136, Italy.<br /><searchLink fieldCode="AU" term="%22Giani+C%22">Giani C</searchLink>; Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy; University of Milano, Via Festa del Perdono 7, Milano 20122, Italy.<br /><searchLink fieldCode="AU" term="%22Gronchi+A%22">Gronchi A</searchLink>; Department of Surgery, Sarcoma Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Grassi+M%22">Grassi M</searchLink>; Department of Medical Oncology, IRCCS Ospedale Policlinico San Martino, Largo R. Benzi, 10, Genova 16132, Italy.<br /><searchLink fieldCode="AU" term="%22Ibrahim+T%22">Ibrahim T</searchLink>; Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Ivanescu+A%22">Ivanescu A</searchLink>; Associazione EHE Italia, Concorezzo, MB 20863, Italy.<br /><searchLink fieldCode="AU" term="%22Ignazzi+G%22">Ignazzi G</searchLink>; Italian Sarcoma Group, Via Vanzetti 5, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Incorvaia+L%22">Incorvaia L</searchLink>; Department of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), Section of Medical Oncology, University of Palermo, Via Liborio Giuffrè 5, Palermo 90127, Italy.<br /><searchLink fieldCode="AU" term="%22Linari+A%22">Linari A</searchLink>; Pathology Unit, Città della Salute e della Scienza di Torino, Corso Bramante 88, Torino 10126, Italy.<br /><searchLink fieldCode="AU" term="%22Luksch+R%22">Luksch R</searchLink>; Pediatric Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Marrari+A%22">Marrari A</searchLink>; Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Mazzocca+A%22">Mazzocca A</searchLink>; Department of Medical Oncology, Policlinico Universitario Campus Bio-Medico and Università Campus Bio-Medico, via Álvaro del Portillo 200, Roma 00128, Italy.<br /><searchLink fieldCode="AU" term="%22Milano+GM%22">Milano GM</searchLink>; Division of Pediatric Hematology and Oncology, Bambino Gesù Children's Hospital, IRCCS, Piazza di Sant'Onofrio 4, Roma 00165, Italy.<br /><searchLink fieldCode="AU" term="%22Morosi+C%22">Morosi C</searchLink>; Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Nannini+M%22">Nannini M</searchLink>; Department of Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Via Giuseppe Massarenti, 9, Bologna 40138, Italy.<br /><searchLink fieldCode="AU" term="%22Navarria+P%22">Navarria P</searchLink>; Department of Radiation Therapy, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, MI 20089, Italy.<br /><searchLink fieldCode="AU" term="%22Palassini+E%22">Palassini E</searchLink>; Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Palmerini+E%22">Palmerini E</searchLink>; Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy; Sylvester Comprehensive Cancer Center, University of Miami, 1475 NW 12th Ave, Miami, FL 33136, USA; Miller School of Medicine, University of Miami, 1475 NW 12th Ave, Miami, FL 33136, USA.<br /><searchLink fieldCode="AU" term="%22Paloschi+F%22">Paloschi F</searchLink>; Fondazione Italiana GIST ETS, Via G Venezian 1, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Pantaleo+MA%22">Pantaleo MA</searchLink>; Department of Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, University of Bologna, Via Giuseppe Massarenti, 9, Bologna 40138, Italy.<br /><searchLink fieldCode="AU" term="%22Pasquali+S%22">Pasquali S</searchLink>; Department of Surgery, Sarcoma Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy; Molecular Pharmacology, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Giovanni Antonio Amadeo 42, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Pavese+V%22">Pavese V</searchLink>; Department of Oncology, University of Torino, Regione Gonzole 10, Orbassano, TO 10043, Italy; AOU San Luigi Gonzaga, Regione Gonzole 10, Orbassano, TO 10043, Italy.<br /><searchLink fieldCode="AU" term="%22Pozzo+E%22">Pozzo E</searchLink>; Department of Radiation Therapy, IRCCS Humanitas Research Hospital, Via Manzoni 56, Rozzano, MI 20089, Italy.<br /><searchLink fieldCode="AU" term="%22Quagliuolo+V%22">Quagliuolo V</searchLink>; Sarcoma, Melanoma and Rare Tumors Surgery Unit, IRCCS Humanitas Research Hospital, Rozzano, Via Manzoni 56, Rozzano, MI 20089, Italy.<br /><searchLink fieldCode="AU" term="%22Quirino+M%22">Quirino M</searchLink>; Medical Oncology, Policlinico Gemelli, Largo Agostino Gemelli 8, Roma 00136, Italy.<br /><searchLink fieldCode="AU" term="%22Sanfilippo+R%22">Sanfilippo R</searchLink>; Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy.<br /><searchLink fieldCode="AU" term="%22Santoro+F%22">Santoro F</searchLink>; Pathology Unit, Città della Salute e della Scienza di Torino, Corso Bramante 88, Torino 10126, Italy.<br /><searchLink fieldCode="AU" term="%22Scotlandi+K%22">Scotlandi K</searchLink>; Laboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, Via G.C. Pupilli 1, Bologna 40136, Italy.<br /><searchLink fieldCode="AU" term="%22Serra+M%22">Serra M</searchLink>; Department of Pathology, IRCCS Istituto Ortopedico Rizzoli, Via G.C. Pupilli 1, Bologna 40136, Italy.<br /><searchLink fieldCode="AU" term="%22Setola+E%22">Setola E</searchLink>; Department of Medical Oncology, IRCCS Istituto Europeo Oncologia, Via Giuseppe Ripamonti 435, Milano 20141, Italy.<br /><searchLink fieldCode="AU" term="%22Strippoli+S%22">Strippoli S</searchLink>; Rare Tumors and Melanoma Unit, I.R.C.C.S. Istituto Tumori 'Giovanni Paolo II', Viale Orazio Flacco 65, Bari 70124, Italy.<br /><searchLink fieldCode="AU" term="%22Tafuto+S%22">Tafuto S</searchLink>; Department of Sarcomas and Rare Tumors, Istituto Nazionale Tumori - IRCCS, Fondazione 'G.Pascale', Via Mariano Semmola 52, Napoli 80131, Italy.<br /><searchLink fieldCode="AU" term="%22Tirtei+E%22">Tirtei E</searchLink>; Pediatric Onco-Hematology, Ospedale Infantile Regina Margherita & Departmento of Sciences of Public Health and Pediatrics, Univeristy of Torino, Piazza Polonia 94, Torino 10126, Italy.<br /><searchLink fieldCode="AU" term="%22Vanni+S%22">Vanni S</searchLink>; Preclinic and Osteoncology Unit, Biosciences Laboratory, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Via Piero Maroncelli 40, Meldola 47014, Italy.<br /><searchLink fieldCode="AU" term="%22Vincenzi+B%22">Vincenzi B</searchLink>; Department of Medical Oncology, Policlinico Universitario Campus Bio-Medico and Università Campus Bio-Medico, via Álvaro del Portillo 200, Roma 00128, Italy.<br /><searchLink fieldCode="AU" term="%22Maestro+R%22">Maestro R</searchLink>; Unit of Oncogenetics and Functional Oncogenomics, IRCCS Centro di Riferimento Oncologico di Aviano, , Via Franco Gallini 2, Aviano, PN 33081, Italy.<br /><searchLink fieldCode="AU" term="%22Dei+Tos+AP%22">Dei Tos AP</searchLink>; Department of Integrated Diagnostics, Azienda Ospedale-Università Padova, Via A.Gabelli, 61, Padova 35128, Italy; Department of Medicine, University of Padova School of Medicine, Via A.Gabelli, 61, Padova 35128, Italy.<br /><searchLink fieldCode="AU" term="%22Stacchiotti+S%22">Stacchiotti S</searchLink>; Medical Oncology Unit 2, Fondazione IRCCS Istituto Nazionale dei Tumori, Via G Venezian 1, Milano 20133, Italy.
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  Data: <searchLink fieldCode="JN" term="%228916049%22">Critical reviews in oncology/hematology</searchLink> [Crit Rev Oncol Hematol] 2025 Dec; Vol. 216, pp. 104960. <i>Date of Electronic Publication: </i>2025 Sep 23.
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  Data: Journal Article; Review; Consensus Statement
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Scientific+Publishers%22">Elsevier Scientific Publishers </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8916049 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0461 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210408428%22">10408428 </searchLink><i>NLM ISO Abbreviation: </i>Crit Rev Oncol Hematol <i>Subsets: </i>MEDLINE
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              Text: 2025 Dec
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