Use of a molecular syndromic panel for the etiological diagnosis of ventilator-associated bacterial pneumonia: impact on clinical outcomes and antibiotic use from a multicenter, prospective study.
Saved in:
| Title: | Use of a molecular syndromic panel for the etiological diagnosis of ventilator-associated bacterial pneumonia: impact on clinical outcomes and antibiotic use from a multicenter, prospective study. |
|---|---|
| Authors: | Giacobbe DR; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy. danieleroberto.giacobbe@unige.it.; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy. danieleroberto.giacobbe@unige.it., Cattardico G; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Bartalucci C; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy., Di Pilato V; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.; UO Microbiologia, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Muccio M; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Limongelli A; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Signori A; Section of Biostatistics, Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy., Bandera A; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.; Infectious Diseases Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Cacopardo B; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy., Campanella E; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy., Caroli A; Dipartimento Di Scienze Biotecnologiche Di Base, Cliniche Intensivologiche E Perioperatorie, Università Cattolica del Sacro Cuore, Rome, Italy.; Dipartimento Di Scienze Dell'Emergenza, Anestesiologiche E Della Rianimazione, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Cattelan A; Infectious and Tropical Diseases Unit, Padua University Hospital, Padua, Italy., Colaneri M; Department of Biomedical and Clinical Sciences L. Sacco, University of Milan, Milan, Italy., Cortegiani A; Department of Precision Medicine in Medical, Surgical and Critical Care Area (Me.Pre.C.C.), University of Palermo, Palermo, Italy.; Department of Anaesthesia, Intensive Care and Emergency Policlinico Paolo Giaccone, Palermo, Italy., Curci L; Department of Medicine, Infectious Diseases Clinic, Santa Maria Della Misericordia Hospital, University of Perugia, Perugia, Italy., De Pascale G; Dipartimento Di Scienze Biotecnologiche Di Base, Cliniche Intensivologiche E Perioperatorie, Università Cattolica del Sacro Cuore, Rome, Italy.; Dipartimento Di Scienze Dell'Emergenza, Anestesiologiche E Della Rianimazione, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., De Socio GV; Department of Medicine, Infectious Diseases Clinic, Santa Maria Della Misericordia Hospital, University of Perugia, Perugia, Italy., Del Puente F; Department of Infectious Diseases, Galliera Hospital, Genoa, Italy., Di Fede A; Department of Precision Medicine in Medical, Surgical and Critical Care Area (Me.Pre.C.C.), University of Palermo, Palermo, Italy., Fanelli C; Department of Medicine, Surgery, and Pharmacy, University of Sassari, Sassari, Italy., Geremia N; Unit of Infectious Diseases, Department of Clinical Medicine, Ospedale 'Dell'Angelo', Venice, Italy.; Unit of Infectious Diseases, Department of Clinical Medicine, Ospedale Civile 'S.S. Giovanni E Paolo', Venice, Italy., Giannella M; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.; Infectious Disease Unit, Department for Integrated Risk Management, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy., Grasselli G; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.; Department of Anaesthesiology, Critical Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Maci C; Vita-Salute San Raffaele University, Milan, Italy., Maida I; Department of Medicine, Surgery, and Pharmacy, University of Sassari, Sassari, Italy., Mangioni D; Infectious Diseases Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Marino A; Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy., Mazzitelli M; Infectious and Tropical Diseases Unit, Padua University Hospital, Padua, Italy., Meloni MC; Department of Medicine, Surgery, and Pharmacy, University of Sassari, Sassari, Italy., Merli M; SC Malattie Infettive, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy., Momesso E; Azienda ULSS4 Veneto Orientale, UOC Anestesia E Rianimazione, Ospedale Di San Donà Di Piave, Piave, Italy., Oltolini C; SC Malattie Infettive, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy., Pallotto C; Department of Medicine, Infectious Diseases Clinic, Santa Maria Della Misericordia Hospital, University of Perugia, Perugia, Italy., Panese S; Unit of Infectious Diseases, Department of Clinical Medicine, Ospedale 'Dell'Angelo', Venice, Italy.; Unit of Infectious Diseases, Department of Clinical Medicine, Ospedale Civile 'S.S. Giovanni E Paolo', Venice, Italy., Passerini M; Department of Infectious Disease, Luigi Sacco Hospital, ASST-FBF-Sacco, Milan, Italy.; Department of Pathophysiology and Transplantation, University of Milano, Milan, Italy., Pontali E; Department of Infectious Diseases, Galliera Hospital, Genoa, Italy., Riccucci D; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy., Rinaldi M; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, Italy.; Infectious Disease Unit, Department for Integrated Risk Management, IRCCS Azienda Ospedaliero-Universitaria Di Bologna, Bologna, Italy., Ripa M; Vita-Salute San Raffaele University, Milan, Italy.; Unit of Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy., Scaglione V; Infectious and Tropical Diseases Unit, Padua University Hospital, Padua, Italy., Serino FS; Azienda ULSS4 Veneto Orientale, UOS Malattie Infettive, UOC Medicina, Portogruaro, Italy., Spagnuolo V; Vita-Salute San Raffaele University, Milan, Italy.; Unit of Infectious Diseases, IRCCS San Raffaele Scientific Institute, Milan, Italy., Spurio G; Department of Precision Medicine in Medical, Surgical and Critical Care Area (Me.Pre.C.C.), University of Palermo, Palermo, Italy., Tigano S; Department of Infectious Diseases, Galliera Hospital, Genoa, Italy., Torti C; Dipartimento Di Scienze Mediche E Chirurgiche, UOC Malattie Infettive, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.; Dipartimento Di Sicurezza E Bioetica, Università Cattolica del Sacro Cuore, Sez. Malattie Infettive, Rome, Italy., Travi G; SC Malattie Infettive, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy., Magnasco L; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Portunato F; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Briano F; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Mikulska M; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Ball L; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Robba C; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Patroniti N; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Battaglini D; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.; Anesthesia and Intensive Care, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Giacomini M; Department of Informatics, Bioengineering, Robotics and System Engineering (DIBRIS), University of Genoa, Genoa, Italy., Rossolini GM; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Microbiology and Virology Unit, Florence Careggi University Hospital, Florence, Italy., Sanguinetti M; Dipartimento Di Scienze Biotecnologiche Di Base, Cliniche Intensivologiche E Perioperatorie, Università Cattolica del Sacro Cuore, Rome, Italy.; Dipartimento Di Scienze Di Laboratorio Ed Ematologiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Morici P; UO Microbiologia, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Marchese A; Department of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, Genoa, Italy.; UO Microbiologia, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Vena A; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Bassetti M; Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy.; Clinica Malattie Infettive, IRCCS Ospedale Policlinico San Martino, Genoa, Italy. |
| Corporate Authors: | RAPID-SITA PHENOTYPES investigators |
| Source: | Critical care (London, England) [Crit Care] 2025 Sep 25; Vol. 29 (1), pp. 403. Date of Electronic Publication: 2025 Sep 25. |
| Publication Type: | Journal Article; Multicenter Study; Observational Study |
| Journal Info: | Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 9801902 Publication Model: Electronic Cited Medium: Internet ISSN: 1466-609X (Electronic) Linking ISSN: 13648535 NLM ISO Abbreviation: Crit Care Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 1466-609X |
|---|---|
| DOI: | 10.1186/s13054-025-05632-z |
