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Nexiguran Ziclumeran Gene Editing in Hereditary ATTR with Polyneuropathy.

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Title: Nexiguran Ziclumeran Gene Editing in Hereditary ATTR with Polyneuropathy.
Authors: Gillmore JD; University College London, National Amyloidosis Centre, Royal Free Hospital, London., Gane E; University of Auckland, Auckland, New Zealand., Täubel J; Richmond Pharmacology, London., Pilebro B; Umeå University, Umeå, Sweden., Echaniz-Laguna A; Bicêtre University Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris-Saclay, Le Kremlin-Bicêtre, France., Kao J; Auckland City Hospital, Auckland, New Zealand., Litchy W; Mayo Clinic, Rochester, MN., Shahda S; Intellia Therapeutics, Cambridge, MA., Haagensen A; Intellia Therapeutics, Cambridge, MA., Walsh L; Intellia Therapeutics, Cambridge, MA., Smith D; Intellia Therapeutics, Cambridge, MA., Kachadourian J; Intellia Therapeutics, Cambridge, MA., Ward JH; Intellia Therapeutics, Cambridge, MA., Lebwohl D; Intellia Therapeutics, Cambridge, MA., Zhu P; Intellia Therapeutics, Cambridge, MA., Xu Y; Intellia Therapeutics, Cambridge, MA., Leung A; Intellia Therapeutics, Cambridge, MA., Sonderfan A; Intellia Therapeutics, Cambridge, MA., Gutstein DE; Regeneron Pharmaceuticals, Tarrytown, NY., Manvelian G; Regeneron Pharmaceuticals, Tarrytown, NY., Adams D; Bicêtre University Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
Source: The New England journal of medicine [N Engl J Med] 2025 Oct 09; Vol. 393 (14), pp. 1375-1386. Date of Electronic Publication: 2025 Sep 25.
Publication Type: Journal Article; Clinical Trial, Phase I; Multicenter Study
Journal Info: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Gillmore+JD%22">Gillmore JD</searchLink>; University College London, National Amyloidosis Centre, Royal Free Hospital, London.<br /><searchLink fieldCode="AU" term="%22Gane+E%22">Gane E</searchLink>; University of Auckland, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Täubel+J%22">Täubel J</searchLink>; Richmond Pharmacology, London.<br /><searchLink fieldCode="AU" term="%22Pilebro+B%22">Pilebro B</searchLink>; Umeå University, Umeå, Sweden.<br /><searchLink fieldCode="AU" term="%22Echaniz-Laguna+A%22">Echaniz-Laguna A</searchLink>; Bicêtre University Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris-Saclay, Le Kremlin-Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Kao+J%22">Kao J</searchLink>; Auckland City Hospital, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Litchy+W%22">Litchy W</searchLink>; Mayo Clinic, Rochester, MN.<br /><searchLink fieldCode="AU" term="%22Shahda+S%22">Shahda S</searchLink>; Intellia Therapeutics, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Haagensen+A%22">Haagensen A</searchLink>; Intellia Therapeutics, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Walsh+L%22">Walsh L</searchLink>; Intellia Therapeutics, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Smith+D%22">Smith D</searchLink>; Intellia Therapeutics, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Kachadourian+J%22">Kachadourian J</searchLink>; Intellia Therapeutics, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Ward+JH%22">Ward JH</searchLink>; Intellia Therapeutics, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Lebwohl+D%22">Lebwohl D</searchLink>; Intellia Therapeutics, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Zhu+P%22">Zhu P</searchLink>; Intellia Therapeutics, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Intellia Therapeutics, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Leung+A%22">Leung A</searchLink>; Intellia Therapeutics, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Sonderfan+A%22">Sonderfan A</searchLink>; Intellia Therapeutics, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Gutstein+DE%22">Gutstein DE</searchLink>; Regeneron Pharmaceuticals, Tarrytown, NY.<br /><searchLink fieldCode="AU" term="%22Manvelian+G%22">Manvelian G</searchLink>; Regeneron Pharmaceuticals, Tarrytown, NY.<br /><searchLink fieldCode="AU" term="%22Adams+D%22">Adams D</searchLink>; Bicêtre University Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris-Saclay, Le Kremlin-Bicêtre, France.
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