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Toxicity Profiling and In Vivo Metabolism of Danshensu-Derived Novel Antihypertensive Candidate 221s (2,9).

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Title: Toxicity Profiling and In Vivo Metabolism of Danshensu-Derived Novel Antihypertensive Candidate 221s (2,9).
Authors: Chen Y; Xi'an Key Laboratory for Research and Development of Innovative Multi-Target Antihypertensive Drugs, Xi'an Innovative Antihypertensive Drugs International Science and Technology Cooperation Base, Xi'an Medical University, Xi'an 710021, China.; Institute of Drug Research, Xi'an Medical University, Xi'an 710021, China.; College of Pharmacy, Xi'an Medical University, Xi'an 710021, China., Yang K; Xi'an Key Laboratory for Research and Development of Innovative Multi-Target Antihypertensive Drugs, Xi'an Innovative Antihypertensive Drugs International Science and Technology Cooperation Base, Xi'an Medical University, Xi'an 710021, China.; Institute of Drug Research, Xi'an Medical University, Xi'an 710021, China.; College of Pharmacy, Xi'an Medical University, Xi'an 710021, China., Yu L; Xi'an Key Laboratory for Research and Development of Innovative Multi-Target Antihypertensive Drugs, Xi'an Innovative Antihypertensive Drugs International Science and Technology Cooperation Base, Xi'an Medical University, Xi'an 710021, China.; Institute of Drug Research, Xi'an Medical University, Xi'an 710021, China.; College of Pharmacy, Xi'an Medical University, Xi'an 710021, China., Wang R; Xi'an Key Laboratory for Research and Development of Innovative Multi-Target Antihypertensive Drugs, Xi'an Innovative Antihypertensive Drugs International Science and Technology Cooperation Base, Xi'an Medical University, Xi'an 710021, China.; Institute of Drug Research, Xi'an Medical University, Xi'an 710021, China.; College of Pharmacy, Xi'an Medical University, Xi'an 710021, China., Liu S; Xi'an Key Laboratory for Research and Development of Innovative Multi-Target Antihypertensive Drugs, Xi'an Innovative Antihypertensive Drugs International Science and Technology Cooperation Base, Xi'an Medical University, Xi'an 710021, China.; Institute of Drug Research, Xi'an Medical University, Xi'an 710021, China.; College of Pharmacy, Xi'an Medical University, Xi'an 710021, China., Qin B; Xi'an Key Laboratory for Research and Development of Innovative Multi-Target Antihypertensive Drugs, Xi'an Innovative Antihypertensive Drugs International Science and Technology Cooperation Base, Xi'an Medical University, Xi'an 710021, China.; Institute of Drug Research, Xi'an Medical University, Xi'an 710021, China.; College of Pharmacy, Xi'an Medical University, Xi'an 710021, China.
Source: Toxins [Toxins (Basel)] 2025 Sep 01; Vol. 17 (9). Date of Electronic Publication: 2025 Sep 01.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101530765 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6651 (Electronic) Linking ISSN: 20726651 NLM ISO Abbreviation: Toxins (Basel) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Toxicity Profiling and In Vivo Metabolism of Danshensu-Derived Novel Antihypertensive Candidate 221s (2,9).
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  Data: <searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Xi'an Key Laboratory for Research and Development of Innovative Multi-Target Antihypertensive Drugs, Xi'an Innovative Antihypertensive Drugs International Science and Technology Cooperation Base, Xi'an Medical University, Xi'an 710021, China.; Institute of Drug Research, Xi'an Medical University, Xi'an 710021, China.; College of Pharmacy, Xi'an Medical University, Xi'an 710021, China.<br /><searchLink fieldCode="AU" term="%22Yang+K%22">Yang K</searchLink>; Xi'an Key Laboratory for Research and Development of Innovative Multi-Target Antihypertensive Drugs, Xi'an Innovative Antihypertensive Drugs International Science and Technology Cooperation Base, Xi'an Medical University, Xi'an 710021, China.; Institute of Drug Research, Xi'an Medical University, Xi'an 710021, China.; College of Pharmacy, Xi'an Medical University, Xi'an 710021, China.<br /><searchLink fieldCode="AU" term="%22Yu+L%22">Yu L</searchLink>; Xi'an Key Laboratory for Research and Development of Innovative Multi-Target Antihypertensive Drugs, Xi'an Innovative Antihypertensive Drugs International Science and Technology Cooperation Base, Xi'an Medical University, Xi'an 710021, China.; Institute of Drug Research, Xi'an Medical University, Xi'an 710021, China.; College of Pharmacy, Xi'an Medical University, Xi'an 710021, China.<br /><searchLink fieldCode="AU" term="%22Wang+R%22">Wang R</searchLink>; Xi'an Key Laboratory for Research and Development of Innovative Multi-Target Antihypertensive Drugs, Xi'an Innovative Antihypertensive Drugs International Science and Technology Cooperation Base, Xi'an Medical University, Xi'an 710021, China.; Institute of Drug Research, Xi'an Medical University, Xi'an 710021, China.; College of Pharmacy, Xi'an Medical University, Xi'an 710021, China.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Xi'an Key Laboratory for Research and Development of Innovative Multi-Target Antihypertensive Drugs, Xi'an Innovative Antihypertensive Drugs International Science and Technology Cooperation Base, Xi'an Medical University, Xi'an 710021, China.; Institute of Drug Research, Xi'an Medical University, Xi'an 710021, China.; College of Pharmacy, Xi'an Medical University, Xi'an 710021, China.<br /><searchLink fieldCode="AU" term="%22Qin+B%22">Qin B</searchLink>; Xi'an Key Laboratory for Research and Development of Innovative Multi-Target Antihypertensive Drugs, Xi'an Innovative Antihypertensive Drugs International Science and Technology Cooperation Base, Xi'an Medical University, Xi'an 710021, China.; Institute of Drug Research, Xi'an Medical University, Xi'an 710021, China.; College of Pharmacy, Xi'an Medical University, Xi'an 710021, China.
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  Data: <searchLink fieldCode="JN" term="%22101530765%22">Toxins</searchLink> [Toxins (Basel)] 2025 Sep 01; Vol. 17 (9). <i>Date of Electronic Publication: </i>2025 Sep 01.
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        Value: 10.3390/toxins17090436
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              M: 09
              Text: 2025 Sep 01
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