View in EDS

Plumbagin improves pulmonary vascular remodeling in PAH via miR-21-5p/MMP/TIMP regulation, with diagnostic implications for cardiac function.

Saved in:
Bibliographic Details
Title: Plumbagin improves pulmonary vascular remodeling in PAH via miR-21-5p/MMP/TIMP regulation, with diagnostic implications for cardiac function.
Authors: Hsieh CC; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Division of Cardiovascular Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Department of Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan., Kuo HF; Department of Internal Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Gangshan Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan., Wang HH; Department of Internal Medicine, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan., Hua MD; National Synchrotron Radiation Research Center, Hsinchu 300, Taiwan., Chen IL; Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan., Lin JL; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan., Lo YC; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan., Lin ZJ; National Synchrotron Radiation Research Center, Hsinchu 300, Taiwan., Chen YH; Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan; Department of Psychology, College of Medical and Health Science, Asia University, Taichung 413, Taiwan., Kuo YR; Department of Plastic and Reconstructive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan., Hsu CH; Department of Internal Medicine, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan; Division of Cardiology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan; Division of Critical Care, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan. Electronic address: chihhsinhsu@gmail.com., Liu PL; Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan; Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan. Electronic address: kisa@kmu.edu.tw.
Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2025 Nov; Vol. 192, pp. 118604. Date of Electronic Publication: 2025 Sep 27.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41016151
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Plumbagin improves pulmonary vascular remodeling in PAH via miR-21-5p/MMP/TIMP regulation, with diagnostic implications for cardiac function.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Hsieh+CC%22">Hsieh CC</searchLink>; Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Division of Cardiovascular Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Department of Surgery, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+HF%22">Kuo HF</searchLink>; Department of Internal Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Gangshan Hospital, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+HH%22">Wang HH</searchLink>; Department of Internal Medicine, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hua+MD%22">Hua MD</searchLink>; National Synchrotron Radiation Research Center, Hsinchu 300, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+IL%22">Chen IL</searchLink>; Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+JL%22">Lin JL</searchLink>; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lo+YC%22">Lo YC</searchLink>; Department of Pharmacology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+ZJ%22">Lin ZJ</searchLink>; National Synchrotron Radiation Research Center, Hsinchu 300, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YH%22">Chen YH</searchLink>; Graduate Institute of Integrated Medicine, College of Chinese Medicine, China Medical University, Taichung 404, Taiwan; Department of Psychology, College of Medical and Health Science, Asia University, Taichung 413, Taiwan.<br /><searchLink fieldCode="AU" term="%22Kuo+YR%22">Kuo YR</searchLink>; Department of Plastic and Reconstructive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 807, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+CH%22">Hsu CH</searchLink>; Department of Internal Medicine, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan; Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan; Division of Cardiology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan; Division of Critical Care, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 701, Taiwan. Electronic address: chihhsinhsu@gmail.com.<br /><searchLink fieldCode="AU" term="%22Liu+PL%22">Liu PL</searchLink>; Department of Respiratory Therapy, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan; Regenerative Medicine and Cell Therapy Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan. Electronic address: kisa@kmu.edu.tw.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%228213295%22">Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie</searchLink> [Biomed Pharmacother] 2025 Nov; Vol. 192, pp. 118604. <i>Date of Electronic Publication: </i>2025 Sep 27.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editions+Scientifiques+Elsevier%22">Editions Scientifiques Elsevier </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>8213295 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1950-6007 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207533322%22">07533322 </searchLink><i>NLM ISO Abbreviation: </i>Biomed Pharmacother <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41016151
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.biopha.2025.118604
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 118604
    Titles:
      – TitleFull: Plumbagin improves pulmonary vascular remodeling in PAH via miR-21-5p/MMP/TIMP regulation, with diagnostic implications for cardiac function.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Hsieh CC
      – PersonEntity:
          Name:
            NameFull: Kuo HF
      – PersonEntity:
          Name:
            NameFull: Wang HH
      – PersonEntity:
          Name:
            NameFull: Hua MD
      – PersonEntity:
          Name:
            NameFull: Chen IL
      – PersonEntity:
          Name:
            NameFull: Lin JL
      – PersonEntity:
          Name:
            NameFull: Lo YC
      – PersonEntity:
          Name:
            NameFull: Lin ZJ
      – PersonEntity:
          Name:
            NameFull: Chen YH
      – PersonEntity:
          Name:
            NameFull: Kuo YR
      – PersonEntity:
          Name:
            NameFull: Hsu CH
      – PersonEntity:
          Name:
            NameFull: Liu PL
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 11
              Text: 2025 Nov
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1950-6007
          Numbering:
            – Type: volume
              Value: 192
          Titles:
            – TitleFull: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
              Type: main
ResultId 1