Genetic mutations in HSV-1 replication-defective vectors: Implications for their safety in gene therapy applications.
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| Title: | Genetic mutations in HSV-1 replication-defective vectors: Implications for their safety in gene therapy applications. |
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| Authors: | Cattaneo S; Vita-Salute San Raffaele University, Milan, Italy.; IRCCS Neuromed, Pozzilli, Italy., Bettegazzi B; Vita-Salute San Raffaele University, Milan, Italy. bettegazzi.barbara@hsr.it.; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy. bettegazzi.barbara@hsr.it., Ingusci S; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Verlengia G; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Department of Neuroscience and Rehabilitation, Section of Pharmacology, University of Ferrara, Ferrara, Italy., Tascini AS; Vita-Salute San Raffaele University, Milan, Italy.; Center for Omics Sciences COSR, BioInformatics Laboratory, San Raffaele Scientific Institute, Milan, Italy., Zucchini S; Department of Neuroscience and Rehabilitation, Section of Pharmacology, University of Ferrara, Ferrara, Italy., Codazzi F; Vita-Salute San Raffaele University, Milan, Italy.; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy., Morelli MJ; Center for Omics Sciences COSR, BioInformatics Laboratory, San Raffaele Scientific Institute, Milan, Italy., Marzulli M; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Glorioso JC; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Simonato M; Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.; Department of Neuroscience and Rehabilitation, Section of Pharmacology, University of Ferrara, Ferrara, Italy. |
| Source: | Gene therapy [Gene Ther] 2025 Dec; Vol. 32 (6), pp. 581-593. Date of Electronic Publication: 2025 Sep 28. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5462 (Electronic) Linking ISSN: 09697128 NLM ISO Abbreviation: Gene Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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