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Skeletal Muscle Biomarkers of Amyotrophic Lateral Sclerosis: A Large-Scale, Multi-Cohort Proteomic Study.

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Title: Skeletal Muscle Biomarkers of Amyotrophic Lateral Sclerosis: A Large-Scale, Multi-Cohort Proteomic Study.
Authors: Dergai O; Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, Basel, Switzerland., Wuu J; Department of Neurology and ALS Center, University of Miami Miller School of Medicine, Miami, FL, USA., Koziczak-Holbro M; Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, Basel, Switzerland., Malaspina A; UCL Queen Square Motor Neuron Disease Center, UCL Queen Square Institute of Neurology, University College London, Queen Square, London, UK., Granit V; Department of Neurology and ALS Center, University of Miami Miller School of Medicine, Miami, FL, USA., Hernandez JP; Department of Neurology and ALS Center, University of Miami Miller School of Medicine, Miami, FL, USA., Cooley A; Department of Neurology and ALS Center, University of Miami Miller School of Medicine, Miami, FL, USA., Sachdev R; Biomarker Development, Novartis Biomedical Research, Basel, Switzerland., Yu L; Biomarker Development, Novartis Biomedical Research, Cambridge, MA, USA., Bidinosti M; Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, Basel, Switzerland., Flotte L; Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, Basel, Switzerland., Nash M; Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, Basel, Switzerland., Jennings LL; Disease Area X, Novartis Biomedical Research, Cambridge, MA, USA., Berry JD; Sean M. Healey and AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA., Bruijn LI; Biomarker Development, Novartis Pharmaceuticals, London, UK., Brachat S; Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, Basel, Switzerland., Benatar M; Department of Neurology and ALS Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Source: Annals of neurology [Ann Neurol] 2026 Feb; Vol. 99 (2), pp. 393-407. Date of Electronic Publication: 2025 Sep 29.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7707449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8249 (Electronic) Linking ISSN: 03645134 NLM ISO Abbreviation: Ann Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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              Text: 2026 Feb
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