View in EDS HTML Full Text PDF Full Text

Amyloid beta and tau are associated with the dual effect of neuroinflammation on neurodegeneration.

Saved in:
Bibliographic Details
Title: Amyloid beta and tau are associated with the dual effect of neuroinflammation on neurodegeneration.
Authors: Povala G; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Bellaver B; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Bastiani MA; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil., Ferrari-Souza JP; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil., Aguzzoli CS; Brain Institute of Rio Grande do Sul, PUCRS, Porto Alegre, Rio Grande do Sul, Brazil.; Global Brain Health Institute, University of California, San Francisco, California, USA., Leffa DT; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Ferreira PCL; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Lussier FZ; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Rocha A; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Zalzale H; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Soares C; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Bauer-Negrini G; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Therriault J; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada., Rahmouni N; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada., Stevenson J; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada., Servaes S; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada., Tissot C; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada., Zatt B; Graduate Program in Computing, Universidade Federal de Pelotas (UFPEL), Pelotas, Rio Grande do Sul, Brazil., Karikari TK; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden., Ikonomovic MD; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Geriatric Research Education and Clinical Center, VA Pittsburgh HS, Pittsburgh, Pennsylvania, USA., Villemagne VL; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Gauthier S; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada., Zimmer ER; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.; Brain Institute of Rio Grande do Sul, PUCRS, Porto Alegre, Rio Grande do Sul, Brazil.; Department of Pharmacology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.; Graduate Program in Biological Sciences: Pharmacology and Therapeutics, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil., Tudorascu DL; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Biostatistics, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Benedet AL; Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden., Rosa-Neto P; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada.; Brain Imaging Centre, Montreal Neurological Institute-Hospital, Montreal, Quebec, Canada.; Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, Texas, USA., Pascoal TA; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Oct; Vol. 21 (10), pp. e70746.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41020416
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Amyloid beta and tau are associated with the dual effect of neuroinflammation on neurodegeneration.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Povala+G%22">Povala G</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Bellaver+B%22">Bellaver B</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Bastiani+MA%22">Bastiani MA</searchLink>; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.<br /><searchLink fieldCode="AU" term="%22Ferrari-Souza+JP%22">Ferrari-Souza JP</searchLink>; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.<br /><searchLink fieldCode="AU" term="%22Aguzzoli+CS%22">Aguzzoli CS</searchLink>; Brain Institute of Rio Grande do Sul, PUCRS, Porto Alegre, Rio Grande do Sul, Brazil.; Global Brain Health Institute, University of California, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Leffa+DT%22">Leffa DT</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Ferreira+PCL%22">Ferreira PCL</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Lussier+FZ%22">Lussier FZ</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Rocha+A%22">Rocha A</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Zalzale+H%22">Zalzale H</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Soares+C%22">Soares C</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Bauer-Negrini+G%22">Bauer-Negrini G</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Therriault+J%22">Therriault J</searchLink>; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Rahmouni+N%22">Rahmouni N</searchLink>; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Stevenson+J%22">Stevenson J</searchLink>; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Servaes+S%22">Servaes S</searchLink>; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Tissot+C%22">Tissot C</searchLink>; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Zatt+B%22">Zatt B</searchLink>; Graduate Program in Computing, Universidade Federal de Pelotas (UFPEL), Pelotas, Rio Grande do Sul, Brazil.<br /><searchLink fieldCode="AU" term="%22Karikari+TK%22">Karikari TK</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Ikonomovic+MD%22">Ikonomovic MD</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Geriatric Research Education and Clinical Center, VA Pittsburgh HS, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Villemagne+VL%22">Villemagne VL</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Gauthier+S%22">Gauthier S</searchLink>; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Zimmer+ER%22">Zimmer ER</searchLink>; Graduate Program in Biological Sciences: Biochemistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.; Brain Institute of Rio Grande do Sul, PUCRS, Porto Alegre, Rio Grande do Sul, Brazil.; Department of Pharmacology, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.; Graduate Program in Biological Sciences: Pharmacology and Therapeutics, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.<br /><searchLink fieldCode="AU" term="%22Tudorascu+DL%22">Tudorascu DL</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Biostatistics, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Benedet+AL%22">Benedet AL</searchLink>; Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.<br /><searchLink fieldCode="AU" term="%22Rosa-Neto+P%22">Rosa-Neto P</searchLink>; Translational Neuroimaging Laboratory, McGill University Research Centre for Studies in Aging, Alzheimer's Disease Research Unit, Douglas Research Institute, Le Centre intégré universitaire de santé et de services sociaux (CIUSSS) de l'Ouest-de-l'Île-de-Montréal, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, Psychiatry and Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada.; Brain Imaging Centre, Montreal Neurological Institute-Hospital, Montreal, Quebec, Canada.; Peter O'Donnell Jr. Brain Institute, University of Texas Southwestern Medical Center, Dallas, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Pascoal+TA%22">Pascoal TA</searchLink>; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Department of Neurology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101231978%22">Alzheimer's & dementia : the journal of the Alzheimer's Association</searchLink> [Alzheimers Dement] 2025 Oct; Vol. 21 (10), pp. e70746.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Ltd%22">John Wiley & Sons, Ltd </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101231978 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-5279 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215525260%22">15525260 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41020416
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1002/alz.70746
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e70746
    Titles:
      – TitleFull: Amyloid beta and tau are associated with the dual effect of neuroinflammation on neurodegeneration.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Povala G
      – PersonEntity:
          Name:
            NameFull: Bellaver B
      – PersonEntity:
          Name:
            NameFull: Bastiani MA
      – PersonEntity:
          Name:
            NameFull: Ferrari-Souza JP
      – PersonEntity:
          Name:
            NameFull: Aguzzoli CS
      – PersonEntity:
          Name:
            NameFull: Leffa DT
      – PersonEntity:
          Name:
            NameFull: Ferreira PCL
      – PersonEntity:
          Name:
            NameFull: Lussier FZ
      – PersonEntity:
          Name:
            NameFull: Rocha A
      – PersonEntity:
          Name:
            NameFull: Zalzale H
      – PersonEntity:
          Name:
            NameFull: Soares C
      – PersonEntity:
          Name:
            NameFull: Bauer-Negrini G
      – PersonEntity:
          Name:
            NameFull: Therriault J
      – PersonEntity:
          Name:
            NameFull: Rahmouni N
      – PersonEntity:
          Name:
            NameFull: Stevenson J
      – PersonEntity:
          Name:
            NameFull: Servaes S
      – PersonEntity:
          Name:
            NameFull: Tissot C
      – PersonEntity:
          Name:
            NameFull: Zatt B
      – PersonEntity:
          Name:
            NameFull: Karikari TK
      – PersonEntity:
          Name:
            NameFull: Ikonomovic MD
      – PersonEntity:
          Name:
            NameFull: Villemagne VL
      – PersonEntity:
          Name:
            NameFull: Gauthier S
      – PersonEntity:
          Name:
            NameFull: Zimmer ER
      – PersonEntity:
          Name:
            NameFull: Tudorascu DL
      – PersonEntity:
          Name:
            NameFull: Benedet AL
      – PersonEntity:
          Name:
            NameFull: Rosa-Neto P
      – PersonEntity:
          Name:
            NameFull: Pascoal TA
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 10
              Text: 2025 Oct
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1552-5279
          Numbering:
            – Type: volume
              Value: 21
            – Type: issue
              Value: 10
          Titles:
            – TitleFull: Alzheimer's & dementia : the journal of the Alzheimer's Association
              Type: main
ResultId 1