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Continuous Positive Airway Pressure and Progression of Enlarged Perivascular Spaces in Adults With Obstructive Sleep Apnea.

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Title: Continuous Positive Airway Pressure and Progression of Enlarged Perivascular Spaces in Adults With Obstructive Sleep Apnea.
Authors: Sommer R; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada., Hill EA; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom.; Sleep Research Unit, Department of Sleep Medicine, Royal Infirmary of Edinburgh, United Kingdom.; School of Applied Sciences, University of the West of England (UWE), Bristol, United Kingdom., Ramirez J; Cognitive Neurology Research Unit, Dr. Sandra Black Centre for Brain Resilience and Recovery, Sunnybrook Research Institute, University of Toronto, Ontario, Canada., Coello RD; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom., Ballerini L; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom., Gibson E; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.; Cognitive Neurology Research Unit, Dr. Sandra Black Centre for Brain Resilience and Recovery, Sunnybrook Research Institute, University of Toronto, Ontario, Canada., Berberian S; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.; Cognitive Neurology Research Unit, Dr. Sandra Black Centre for Brain Resilience and Recovery, Sunnybrook Research Institute, University of Toronto, Ontario, Canada., Valdés Hernández MDC; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom., Centen A; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada., Chappell FM; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom., Montazeri N; Department of Electrical and Computer Engineering, Queens University, Kingston, Ontario, Canada., Stringer MS; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom., Thrippleton M; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom., Jaime Garcia D; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom., Wiseman S; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom., Narayansingh M; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada., Tandon A; Division of Respirology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada., Boulos MI; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada., Murray BJ; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada., Doubal F; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom., Riha RL; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom.; Sleep Research Unit, Department of Sleep Medicine, Royal Infirmary of Edinburgh, United Kingdom., Goubran M; Cognitive Neurology Research Unit, Dr. Sandra Black Centre for Brain Resilience and Recovery, Sunnybrook Research Institute, University of Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Ontario, Canada; and.; Physical Sciences Platform, Sunnybrook Research Institute, University of Toronto, Ontario, Canada., Macintosh BJ; Cognitive Neurology Research Unit, Dr. Sandra Black Centre for Brain Resilience and Recovery, Sunnybrook Research Institute, University of Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Ontario, Canada; and., Wardlaw JM; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom., Black SE; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.; Cognitive Neurology Research Unit, Dr. Sandra Black Centre for Brain Resilience and Recovery, Sunnybrook Research Institute, University of Toronto, Ontario, Canada., Lim ASP; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.
Source: Neurology [Neurology] 2025 Oct; Vol. 105 (8), pp. e213955. Date of Electronic Publication: 2025 Sep 29.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0401060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-632X (Electronic) Linking ISSN: 00283878 NLM ISO Abbreviation: Neurology Subsets: MEDLINE
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  Data: Continuous Positive Airway Pressure and Progression of Enlarged Perivascular Spaces in Adults With Obstructive Sleep Apnea.
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  Data: <searchLink fieldCode="AU" term="%22Sommer+R%22">Sommer R</searchLink>; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Hill+EA%22">Hill EA</searchLink>; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom.; Sleep Research Unit, Department of Sleep Medicine, Royal Infirmary of Edinburgh, United Kingdom.; School of Applied Sciences, University of the West of England (UWE), Bristol, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ramirez+J%22">Ramirez J</searchLink>; Cognitive Neurology Research Unit, Dr. Sandra Black Centre for Brain Resilience and Recovery, Sunnybrook Research Institute, University of Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Coello+RD%22">Coello RD</searchLink>; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Ballerini+L%22">Ballerini L</searchLink>; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gibson+E%22">Gibson E</searchLink>; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.; Cognitive Neurology Research Unit, Dr. Sandra Black Centre for Brain Resilience and Recovery, Sunnybrook Research Institute, University of Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Berberian+S%22">Berberian S</searchLink>; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.; Cognitive Neurology Research Unit, Dr. Sandra Black Centre for Brain Resilience and Recovery, Sunnybrook Research Institute, University of Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Valdés+Hernández+MDC%22">Valdés Hernández MDC</searchLink>; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Centen+A%22">Centen A</searchLink>; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Chappell+FM%22">Chappell FM</searchLink>; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Montazeri+N%22">Montazeri N</searchLink>; Department of Electrical and Computer Engineering, Queens University, Kingston, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Stringer+MS%22">Stringer MS</searchLink>; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Thrippleton+M%22">Thrippleton M</searchLink>; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Jaime+Garcia+D%22">Jaime Garcia D</searchLink>; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Wiseman+S%22">Wiseman S</searchLink>; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Narayansingh+M%22">Narayansingh M</searchLink>; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Tandon+A%22">Tandon A</searchLink>; Division of Respirology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Boulos+MI%22">Boulos MI</searchLink>; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Murray+BJ%22">Murray BJ</searchLink>; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Doubal+F%22">Doubal F</searchLink>; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Riha+RL%22">Riha RL</searchLink>; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom.; Sleep Research Unit, Department of Sleep Medicine, Royal Infirmary of Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Goubran+M%22">Goubran M</searchLink>; Cognitive Neurology Research Unit, Dr. Sandra Black Centre for Brain Resilience and Recovery, Sunnybrook Research Institute, University of Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Ontario, Canada; and.; Physical Sciences Platform, Sunnybrook Research Institute, University of Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Macintosh+BJ%22">Macintosh BJ</searchLink>; Cognitive Neurology Research Unit, Dr. Sandra Black Centre for Brain Resilience and Recovery, Sunnybrook Research Institute, University of Toronto, Ontario, Canada.; Department of Medical Biophysics, University of Toronto, Ontario, Canada; and.<br /><searchLink fieldCode="AU" term="%22Wardlaw+JM%22">Wardlaw JM</searchLink>; Centre for Clinical Brain Sciences, Edinburgh Imaging, UK Dementia Research Institute Centre, The University of Edinburgh, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Black+SE%22">Black SE</searchLink>; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.; Cognitive Neurology Research Unit, Dr. Sandra Black Centre for Brain Resilience and Recovery, Sunnybrook Research Institute, University of Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Lim+ASP%22">Lim ASP</searchLink>; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada.
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