A basic framework to explain splice-site choice in eukaryotes. - Dent CI; Prodic S; Balakrishnan A; Chhabra A; Georges JDG; Mukherjee S; Coutts J; Gitonobel M; Sarwade RD; Rosenbluh J; D'Amato M; Das PP; et al. (Nature communications, 2025)