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Significance of Elevated Donor-Derived Cell-Free DNA in Heart Transplant Recipients With Negative Endomyocardial Biopsies: A Dawn of a New Era.

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Title: Significance of Elevated Donor-Derived Cell-Free DNA in Heart Transplant Recipients With Negative Endomyocardial Biopsies: A Dawn of a New Era.
Authors: Moeller CM; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).; Department of Medicine, Icahn School of Medicine at Mount Sinai West and St. Luke's Hospitals, New York, NY (C.M.M.)., Fernandez Valledor A; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).; Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY (A.F.V., D.T.M.).; University of Barcelona, Barcelona, Spain (A.F.V.)., Oren D; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Rahman S; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Baranowska J; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Hertz A; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., DeFilippis EM; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Lee C; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Regan MC; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Oren A; Division of Engineering, Technion-Institute of Technology, Tel Aviv, Israel (A.O.)., Rahman A; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Hennecken C; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Salazar R; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Donald EM; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Lotan D; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Majure DT; Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY (A.F.V., D.T.M.)., Yuzefpolskaya M; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Colombo PC; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Raikhelkar JK; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Fried JA; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Clerkin KJ; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Latif F; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Sayer GT; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.)., Uriel N; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).
Source: Circulation. Heart failure [Circ Heart Fail] 2025 Nov; Vol. 18 (11), pp. e012787. Date of Electronic Publication: 2025 Sep 30.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101479941 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1941-3297 (Electronic) Linking ISSN: 19413289 NLM ISO Abbreviation: Circ Heart Fail Subsets: MEDLINE
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  Data: Significance of Elevated Donor-Derived Cell-Free DNA in Heart Transplant Recipients With Negative Endomyocardial Biopsies: A Dawn of a New Era.
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  Data: <searchLink fieldCode="AU" term="%22Moeller+CM%22">Moeller CM</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).; Department of Medicine, Icahn School of Medicine at Mount Sinai West and St. Luke's Hospitals, New York, NY (C.M.M.).<br /><searchLink fieldCode="AU" term="%22Fernandez+Valledor+A%22">Fernandez Valledor A</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).; Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY (A.F.V., D.T.M.).; University of Barcelona, Barcelona, Spain (A.F.V.).<br /><searchLink fieldCode="AU" term="%22Oren+D%22">Oren D</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Rahman+S%22">Rahman S</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Baranowska+J%22">Baranowska J</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Hertz+A%22">Hertz A</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22DeFilippis+EM%22">DeFilippis EM</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Lee+C%22">Lee C</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Regan+MC%22">Regan MC</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Oren+A%22">Oren A</searchLink>; Division of Engineering, Technion-Institute of Technology, Tel Aviv, Israel (A.O.).<br /><searchLink fieldCode="AU" term="%22Rahman+A%22">Rahman A</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Hennecken+C%22">Hennecken C</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Salazar+R%22">Salazar R</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Donald+EM%22">Donald EM</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Lotan+D%22">Lotan D</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Majure+DT%22">Majure DT</searchLink>; Division of Cardiology, Department of Medicine, Weill Cornell Medicine, New York, NY (A.F.V., D.T.M.).<br /><searchLink fieldCode="AU" term="%22Yuzefpolskaya+M%22">Yuzefpolskaya M</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Colombo+PC%22">Colombo PC</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Raikhelkar+JK%22">Raikhelkar JK</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Fried+JA%22">Fried JA</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Clerkin+KJ%22">Clerkin KJ</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Latif+F%22">Latif F</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Sayer+GT%22">Sayer GT</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).<br /><searchLink fieldCode="AU" term="%22Uriel+N%22">Uriel N</searchLink>; Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, NY (C.M.M., A.F.V., D.O., S.R., J.B., A.H., E.M.D., C.L., M.C.R., A.R., C.H., R.S., E.M.D., D.L., M.Y., P.C.C., J.K.R., J.A.F., K.J.C., F.L., G.T.S., N.U.).
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      – TitleFull: Significance of Elevated Donor-Derived Cell-Free DNA in Heart Transplant Recipients With Negative Endomyocardial Biopsies: A Dawn of a New Era.
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            NameFull: Lee C
      – PersonEntity:
          Name:
            NameFull: Regan MC
      – PersonEntity:
          Name:
            NameFull: Oren A
      – PersonEntity:
          Name:
            NameFull: Rahman A
      – PersonEntity:
          Name:
            NameFull: Hennecken C
      – PersonEntity:
          Name:
            NameFull: Salazar R
      – PersonEntity:
          Name:
            NameFull: Donald EM
      – PersonEntity:
          Name:
            NameFull: Lotan D
      – PersonEntity:
          Name:
            NameFull: Majure DT
      – PersonEntity:
          Name:
            NameFull: Yuzefpolskaya M
      – PersonEntity:
          Name:
            NameFull: Colombo PC
      – PersonEntity:
          Name:
            NameFull: Raikhelkar JK
      – PersonEntity:
          Name:
            NameFull: Fried JA
      – PersonEntity:
          Name:
            NameFull: Clerkin KJ
      – PersonEntity:
          Name:
            NameFull: Latif F
      – PersonEntity:
          Name:
            NameFull: Sayer GT
      – PersonEntity:
          Name:
            NameFull: Uriel N
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 11
              Text: 2025 Nov
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1941-3297
          Numbering:
            – Type: volume
              Value: 18
            – Type: issue
              Value: 11
          Titles:
            – TitleFull: Circulation. Heart failure
              Type: main
ResultId 1