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Estimating Changes in Clinical Outcomes after Discontinuation of Anti-CGRP Targeting Therapy for Migraine Prophylaxis: A Systematic Review and Meta-analysis.

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Title: Estimating Changes in Clinical Outcomes after Discontinuation of Anti-CGRP Targeting Therapy for Migraine Prophylaxis: A Systematic Review and Meta-analysis.
Authors: Makita LM; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil. makitaluana@gmail.com., Fagundes TP; Hospital do Amor Barretos Cancer Hospital, Barretos, Brazil., Reginato PH; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil., Carpinelli LP; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil., de Freitas Morais G; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil., Montanarin RT; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil., de Freitas Kleimmann R; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil., Streit RE; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil., Koppanatham A; Andhra Medical College, Visakhapatnam, India., Rodrigues ACS; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil., Piovesan EJ; Neurology Service, Department of Clinical Medicine, Complex of the Clinical Hospital of the Federal University of Paraná, Curitiba, Brazil.
Source: CNS drugs [CNS Drugs] 2026 Jan; Vol. 40 (1), pp. 71-82. Date of Electronic Publication: 2025 Sep 30.
Publication Type: Journal Article; Systematic Review; Meta-Analysis
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9431220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1934 (Electronic) Linking ISSN: 11727047 NLM ISO Abbreviation: CNS Drugs Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Estimating Changes in Clinical Outcomes after Discontinuation of Anti-CGRP Targeting Therapy for Migraine Prophylaxis: A Systematic Review and Meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Makita+LM%22">Makita LM</searchLink>; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil. makitaluana@gmail.com.<br /><searchLink fieldCode="AU" term="%22Fagundes+TP%22">Fagundes TP</searchLink>; Hospital do Amor Barretos Cancer Hospital, Barretos, Brazil.<br /><searchLink fieldCode="AU" term="%22Reginato+PH%22">Reginato PH</searchLink>; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Carpinelli+LP%22">Carpinelli LP</searchLink>; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Freitas+Morais+G%22">de Freitas Morais G</searchLink>; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Montanarin+RT%22">Montanarin RT</searchLink>; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Freitas+Kleimmann+R%22">de Freitas Kleimmann R</searchLink>; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Streit+RE%22">Streit RE</searchLink>; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Koppanatham+A%22">Koppanatham A</searchLink>; Andhra Medical College, Visakhapatnam, India.<br /><searchLink fieldCode="AU" term="%22Rodrigues+ACS%22">Rodrigues ACS</searchLink>; Complex of the Clinical Hospital of the Federal University of Paraná, General Carneiro Street, 181, Curitiba, Paraná, 80060-900, Brazil.<br /><searchLink fieldCode="AU" term="%22Piovesan+EJ%22">Piovesan EJ</searchLink>; Neurology Service, Department of Clinical Medicine, Complex of the Clinical Hospital of the Federal University of Paraná, Curitiba, Brazil.
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  Data: <searchLink fieldCode="JN" term="%229431220%22">CNS drugs</searchLink> [CNS Drugs] 2026 Jan; Vol. 40 (1), pp. 71-82. <i>Date of Electronic Publication: </i>2025 Sep 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Adis%2C+Springer+International%22">Adis, Springer International </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>9431220 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1179-1934 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211727047%22">11727047 </searchLink><i>NLM ISO Abbreviation: </i>CNS Drugs <i>Subsets: </i>MEDLINE
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              Text: 2026 Jan
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