Early Intratracheal Budesonide to Reduce Bronchopulmonary Dysplasia in Extremely Preterm Infants: The Budesonide in Babies (BiB) Randomized Clinical Trial.
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| Title: | Early Intratracheal Budesonide to Reduce Bronchopulmonary Dysplasia in Extremely Preterm Infants: The Budesonide in Babies (BiB) Randomized Clinical Trial. |
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| Authors: | Ambalavanan N; Division of Neonatology, University of Alabama at Birmingham., Carlo WA; Division of Neonatology, University of Alabama at Birmingham., Nowak KJ; Biostatistics and Epidemiology Division, RTI International, Research Triangle Park, North Carolina., Wiener LE; Biostatistics and Epidemiology Division, RTI International, Research Triangle Park, North Carolina., Cosby SS; Division of Neonatology, University of Alabama at Birmingham., Bhatt AJ; Department of Pediatrics, University of Mississippi Medical Center, Jackson., Watterberg KL; Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque., Poindexter BB; Department of Pediatrics, Emory University, Atlanta, Georgia., Keszler M; Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, Rhode Island., D'Angio CT; Division of Neonatology, University of Rochester School of Medicine and Dentistry, Rochester, New York., Brion LP; Parkland Memorial Hospital, University of Texas Southwestern Medical Center at Dallas., Narendran V; Cincinnati Children's Hospital Medical Center, University of Cincinnati Hospital, Cincinnati, Ohio., Rau CA; University of Utah Health Sciences Center, Salt Lake City., Cotten CM; Department of Pediatrics, Duke University, Durham, North Carolina., Laughon MM; Department of Pediatrics, The University of North Carolina at Chapel Hill., Das A; Social, Statistical and Environmental Sciences Unit, RTI International, Rockville, Maryland., Rysavy MA; McGovern Medical School at The University of Texas Health Science Center at Houston., Hibbs AM; Rainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, Ohio., Fuller J; Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque., Puopolo KM; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Pennsylvania Hospital, Philadelphia., Katheria A; Sharp Mary Birch Hospital for Women & Newborns, San Diego, California., Patel RM; Department of Pediatrics, Emory University, Atlanta, Georgia., Bermick JR; Department of Pediatrics, University of Iowa, Iowa City., Laptook AR; Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, Rhode Island., Prelipcean I; Division of Neonatology, University of Rochester School of Medicine and Dentistry, Rochester, New York., Wyckoff MH; William P. Clements Jr. University Hospital, Dallas, Texas., Moore R; Maynard Children's Hospital, East Carolina University, Greenville, North Carolina., Merhar SL; Good Samaritan Hospital, Cincinnati, Ohio., Ohls RK; University of Utah Health Sciences Center, Salt Lake City., Yoder BA; University of Utah Health Sciences Center, Salt Lake City., Perez M; Ann & Robert H. Prentice Women's Hospital, Lurie Children's Hospital and Northwestern University, Chicago, Illinois., Ghavam S; Virtua Voorhees Hospital, Voorhees, New Jersey., Meyer LR; Sanford Health, Sioux Falls, South Dakota., Chock VY; Lucile Packard Children's Hospital Stanford, Stanford University, Palo Alto, California., DeMauro SB; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Pennsylvania Hospital, Philadelphia., Jackson WM; Department of Pediatrics, The University of North Carolina at Chapel Hill., Handa D; University at Buffalo, Buffalo, New York., Walsh MC; Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland. |
| Corporate Authors: | National Institute of Child Health and Human Development Neonatal Research Network |
| Source: | JAMA [JAMA] 2025 Oct 28; Vol. 334 (16), pp. 1452-1462. |
| Publication Type: | Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial |
| Journal Info: | Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41026481 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Early Intratracheal Budesonide to Reduce Bronchopulmonary Dysplasia in Extremely Preterm Infants: The Budesonide in Babies (BiB) Randomized Clinical Trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ambalavanan+N%22">Ambalavanan N</searchLink>; Division of Neonatology, University of Alabama at Birmingham.<br /><searchLink fieldCode="AU" term="%22Carlo+WA%22">Carlo WA</searchLink>; Division of Neonatology, University of Alabama at Birmingham.<br /><searchLink fieldCode="AU" term="%22Nowak+KJ%22">Nowak KJ</searchLink>; Biostatistics and Epidemiology Division, RTI International, Research Triangle Park, North Carolina.<br /><searchLink fieldCode="AU" term="%22Wiener+LE%22">Wiener LE</searchLink>; Biostatistics and Epidemiology Division, RTI International, Research Triangle Park, North Carolina.<br /><searchLink fieldCode="AU" term="%22Cosby+SS%22">Cosby SS</searchLink>; Division of Neonatology, University of Alabama at Birmingham.<br /><searchLink fieldCode="AU" term="%22Bhatt+AJ%22">Bhatt AJ</searchLink>; Department of Pediatrics, University of Mississippi Medical Center, Jackson.<br /><searchLink fieldCode="AU" term="%22Watterberg+KL%22">Watterberg KL</searchLink>; Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque.<br /><searchLink fieldCode="AU" term="%22Poindexter+BB%22">Poindexter BB</searchLink>; Department of Pediatrics, Emory University, Atlanta, Georgia.<br /><searchLink fieldCode="AU" term="%22Keszler+M%22">Keszler M</searchLink>; Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, Rhode Island.<br /><searchLink fieldCode="AU" term="%22D'Angio+CT%22">D'Angio CT</searchLink>; Division of Neonatology, University of Rochester School of Medicine and Dentistry, Rochester, New York.<br /><searchLink fieldCode="AU" term="%22Brion+LP%22">Brion LP</searchLink>; Parkland Memorial Hospital, University of Texas Southwestern Medical Center at Dallas.<br /><searchLink fieldCode="AU" term="%22Narendran+V%22">Narendran V</searchLink>; Cincinnati Children's Hospital Medical Center, University of Cincinnati Hospital, Cincinnati, Ohio.<br /><searchLink fieldCode="AU" term="%22Rau+CA%22">Rau CA</searchLink>; University of Utah Health Sciences Center, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Cotten+CM%22">Cotten CM</searchLink>; Department of Pediatrics, Duke University, Durham, North Carolina.<br /><searchLink fieldCode="AU" term="%22Laughon+MM%22">Laughon MM</searchLink>; Department of Pediatrics, The University of North Carolina at Chapel Hill.<br /><searchLink fieldCode="AU" term="%22Das+A%22">Das A</searchLink>; Social, Statistical and Environmental Sciences Unit, RTI International, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Rysavy+MA%22">Rysavy MA</searchLink>; McGovern Medical School at The University of Texas Health Science Center at Houston.<br /><searchLink fieldCode="AU" term="%22Hibbs+AM%22">Hibbs AM</searchLink>; Rainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, Ohio.<br /><searchLink fieldCode="AU" term="%22Fuller+J%22">Fuller J</searchLink>; Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque.<br /><searchLink fieldCode="AU" term="%22Puopolo+KM%22">Puopolo KM</searchLink>; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Pennsylvania Hospital, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Katheria+A%22">Katheria A</searchLink>; Sharp Mary Birch Hospital for Women & Newborns, San Diego, California.<br /><searchLink fieldCode="AU" term="%22Patel+RM%22">Patel RM</searchLink>; Department of Pediatrics, Emory University, Atlanta, Georgia.<br /><searchLink fieldCode="AU" term="%22Bermick+JR%22">Bermick JR</searchLink>; Department of Pediatrics, University of Iowa, Iowa City.<br /><searchLink fieldCode="AU" term="%22Laptook+AR%22">Laptook AR</searchLink>; Department of Pediatrics, The Warren Alpert Medical School of Brown University, Providence, Rhode Island.<br /><searchLink fieldCode="AU" term="%22Prelipcean+I%22">Prelipcean I</searchLink>; Division of Neonatology, University of Rochester School of Medicine and Dentistry, Rochester, New York.<br /><searchLink fieldCode="AU" term="%22Wyckoff+MH%22">Wyckoff MH</searchLink>; William P. Clements Jr. University Hospital, Dallas, Texas.<br /><searchLink fieldCode="AU" term="%22Moore+R%22">Moore R</searchLink>; Maynard Children's Hospital, East Carolina University, Greenville, North Carolina.<br /><searchLink fieldCode="AU" term="%22Merhar+SL%22">Merhar SL</searchLink>; Good Samaritan Hospital, Cincinnati, Ohio.<br /><searchLink fieldCode="AU" term="%22Ohls+RK%22">Ohls RK</searchLink>; University of Utah Health Sciences Center, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Yoder+BA%22">Yoder BA</searchLink>; University of Utah Health Sciences Center, Salt Lake City.<br /><searchLink fieldCode="AU" term="%22Perez+M%22">Perez M</searchLink>; Ann & Robert H. Prentice Women's Hospital, Lurie Children's Hospital and Northwestern University, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Ghavam+S%22">Ghavam S</searchLink>; Virtua Voorhees Hospital, Voorhees, New Jersey.<br /><searchLink fieldCode="AU" term="%22Meyer+LR%22">Meyer LR</searchLink>; Sanford Health, Sioux Falls, South Dakota.<br /><searchLink fieldCode="AU" term="%22Chock+VY%22">Chock VY</searchLink>; Lucile Packard Children's Hospital Stanford, Stanford University, Palo Alto, California.<br /><searchLink fieldCode="AU" term="%22DeMauro+SB%22">DeMauro SB</searchLink>; Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Pennsylvania Hospital, Philadelphia.<br /><searchLink fieldCode="AU" term="%22Jackson+WM%22">Jackson WM</searchLink>; Department of Pediatrics, The University of North Carolina at Chapel Hill.<br /><searchLink fieldCode="AU" term="%22Handa+D%22">Handa D</searchLink>; University at Buffalo, Buffalo, New York.<br /><searchLink fieldCode="AU" term="%22Walsh+MC%22">Walsh MC</searchLink>; Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22National+Institute+of+Child+Health+and+Human+Development+Neonatal+Research+Network%22">National Institute of Child Health and Human Development Neonatal Research Network</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227501160%22">JAMA</searchLink> [JAMA] 2025 Oct 28; Vol. 334 (16), pp. 1452-1462. – Name: TypePub Label: Publication Type Group: TypPub Data: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Medical+Association%22">American Medical Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7501160 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-3598 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200987484%22">00987484 </searchLink><i>NLM ISO Abbreviation: </i>JAMA <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41026481 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1001/jama.2025.16450 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1452 Titles: – TitleFull: Early Intratracheal Budesonide to Reduce Bronchopulmonary Dysplasia in Extremely Preterm Infants: The Budesonide in Babies (BiB) Randomized Clinical Trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ambalavanan N – PersonEntity: Name: NameFull: Carlo WA – PersonEntity: Name: NameFull: Nowak KJ – PersonEntity: Name: NameFull: Wiener LE – PersonEntity: Name: NameFull: Cosby SS – PersonEntity: Name: NameFull: Bhatt AJ – PersonEntity: Name: NameFull: Watterberg KL – PersonEntity: Name: NameFull: Poindexter BB – PersonEntity: Name: NameFull: Keszler M – PersonEntity: Name: NameFull: D'Angio CT – PersonEntity: Name: NameFull: Brion LP – PersonEntity: Name: NameFull: Narendran V – PersonEntity: Name: NameFull: Rau CA – PersonEntity: Name: NameFull: Cotten CM – PersonEntity: Name: NameFull: Laughon MM – PersonEntity: Name: NameFull: Das A – PersonEntity: Name: NameFull: Rysavy MA – PersonEntity: Name: NameFull: Hibbs AM – PersonEntity: Name: NameFull: Fuller J – PersonEntity: Name: NameFull: Puopolo KM – PersonEntity: Name: NameFull: Katheria A – PersonEntity: Name: NameFull: Patel RM – PersonEntity: Name: NameFull: Bermick JR – PersonEntity: Name: NameFull: Laptook AR – PersonEntity: Name: NameFull: Prelipcean I – PersonEntity: Name: NameFull: Wyckoff MH – PersonEntity: Name: NameFull: Moore R – PersonEntity: Name: NameFull: Merhar SL – PersonEntity: Name: NameFull: Ohls RK – PersonEntity: Name: NameFull: Yoder BA – PersonEntity: Name: NameFull: Perez M – PersonEntity: Name: NameFull: Ghavam S – PersonEntity: Name: NameFull: Meyer LR – PersonEntity: Name: NameFull: Chock VY – PersonEntity: Name: NameFull: DeMauro SB – PersonEntity: Name: NameFull: Jackson WM – PersonEntity: Name: NameFull: Handa D – PersonEntity: Name: NameFull: Walsh MC IsPartOfRelationships: – BibEntity: Dates: – D: 28 M: 10 Text: 2025 Oct 28 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1538-3598 Numbering: – Type: volume Value: 334 – Type: issue Value: 16 Titles: – TitleFull: JAMA Type: main |
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