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CTLA-4 blockade shifts the B cell repertoire toward autoimmunity.

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Title: CTLA-4 blockade shifts the B cell repertoire toward autoimmunity.
Authors: Çakan E; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA., Wang M; Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut, USA., Dai Y; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA., Mirouse A; Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Villanueva-Pachas CR; Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Bouis D; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA., Boeckers JM; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA., Gera R; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA., Yraita S; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA., Clapp L; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA., Perdigoto AL; Division of Endocrinology and Metabolism, Department of Internal Medicine, Yale University, New Haven, Connecticut, USA., Delmotte FR; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA., Massad C; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA., Bacchiocchi A; Department of Dermatology., Ring AM; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA., Kluger Y; Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut, USA.; Department of Pathology., Kluger HM; Yale Center for Immuno-Oncology.; Yale Cancer Center, and.; Department of Medicine, Yale School of Medicine, New Haven, Connecticut, USA., Herold KC; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.; Division of Endocrinology and Metabolism, Department of Internal Medicine, Yale University, New Haven, Connecticut, USA., Meffre E; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.; Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.
Source: The Journal of clinical investigation [J Clin Invest] 2025 Sep 30; Vol. 135 (22). Date of Electronic Publication: 2025 Sep 30 (Print Publication: 2025).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CTLA-4 blockade shifts the B cell repertoire toward autoimmunity.
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  Data: <searchLink fieldCode="AU" term="%22Çakan+E%22">Çakan E</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Wang+M%22">Wang M</searchLink>; Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Dai+Y%22">Dai Y</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Mirouse+A%22">Mirouse A</searchLink>; Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.<br /><searchLink fieldCode="AU" term="%22Villanueva-Pachas+CR%22">Villanueva-Pachas CR</searchLink>; Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.<br /><searchLink fieldCode="AU" term="%22Bouis+D%22">Bouis D</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Boeckers+JM%22">Boeckers JM</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Gera+R%22">Gera R</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Yraita+S%22">Yraita S</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Clapp+L%22">Clapp L</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Perdigoto+AL%22">Perdigoto AL</searchLink>; Division of Endocrinology and Metabolism, Department of Internal Medicine, Yale University, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Delmotte+FR%22">Delmotte FR</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Massad+C%22">Massad C</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Bacchiocchi+A%22">Bacchiocchi A</searchLink>; Department of Dermatology.<br /><searchLink fieldCode="AU" term="%22Ring+AM%22">Ring AM</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Kluger+Y%22">Kluger Y</searchLink>; Program in Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut, USA.; Department of Pathology.<br /><searchLink fieldCode="AU" term="%22Kluger+HM%22">Kluger HM</searchLink>; Yale Center for Immuno-Oncology.; Yale Cancer Center, and.; Department of Medicine, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Herold+KC%22">Herold KC</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.; Division of Endocrinology and Metabolism, Department of Internal Medicine, Yale University, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Meffre+E%22">Meffre E</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, USA.; Division of Immunology and Rheumatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.
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  Data: <searchLink fieldCode="JN" term="%227802877%22">The Journal of clinical investigation</searchLink> [J Clin Invest] 2025 Sep 30; Vol. 135 (22). <i>Date of Electronic Publication: </i>2025 Sep 30 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7802877 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1558-8238 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219738%22">00219738 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Invest <i>Subsets: </i>MEDLINE
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