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The Role of β-Lactam Antibiotics in Treating Mycobacterium abscessus: From Laboratory Insights to Clinical Applications and the Case for Clinical Trials.

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Title: The Role of β-Lactam Antibiotics in Treating Mycobacterium abscessus: From Laboratory Insights to Clinical Applications and the Case for Clinical Trials.
Authors: Dousa KM; Louis Stokes Cleveland VA Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Shin E; Louis Stokes Cleveland VA Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA., Kurz SG; Division of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, Connecticut, USA., Rubin EJ; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachussetts, USA., Holland SM; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA., Olivier KN; Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA., Daley CL; Division of Mycobacterial and Respiratory Infections, National Jewish Health, Denver, Colorado, USA., Kreiswirth BN; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA., Pottinger PS; Department of Medicine, Division of Allergy & Infectious Diseases, University of Washington School of Medicine, Seattle, Washington, USA., Bonomo RA; Louis Stokes Cleveland VA Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Cleveland, Ohio, USA.; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; GRECC, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.
Source: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2026 Feb 09; Vol. 82 (1), pp. e135-e145.
Publication Type: Journal Article; Review
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9203213 Publication Model: Print Cited Medium: Internet ISSN: 1537-6591 (Electronic) Linking ISSN: 10584838 NLM ISO Abbreviation: Clin Infect Dis Subsets: MEDLINE
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  Data: The Role of β-Lactam Antibiotics in Treating Mycobacterium abscessus: From Laboratory Insights to Clinical Applications and the Case for Clinical Trials.
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  Data: <searchLink fieldCode="AU" term="%22Dousa+KM%22">Dousa KM</searchLink>; Louis Stokes Cleveland VA Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Shin+E%22">Shin E</searchLink>; Louis Stokes Cleveland VA Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Kurz+SG%22">Kurz SG</searchLink>; Division of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Rubin+EJ%22">Rubin EJ</searchLink>; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachussetts, USA.<br /><searchLink fieldCode="AU" term="%22Holland+SM%22">Holland SM</searchLink>; Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Olivier+KN%22">Olivier KN</searchLink>; Division of Pulmonary Diseases and Critical Care Medicine, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Daley+CL%22">Daley CL</searchLink>; Division of Mycobacterial and Respiratory Infections, National Jewish Health, Denver, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Kreiswirth+BN%22">Kreiswirth BN</searchLink>; Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Pottinger+PS%22">Pottinger PS</searchLink>; Department of Medicine, Division of Allergy & Infectious Diseases, University of Washington School of Medicine, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Bonomo+RA%22">Bonomo RA</searchLink>; Louis Stokes Cleveland VA Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; CWRU-Cleveland VAMC Center for Antimicrobial Resistance and Epidemiology (Case VA CARES), Cleveland, Ohio, USA.; Department of Pharmacology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; Department of Proteomics and Bioinformatics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.; GRECC, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, Ohio, USA.
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              Text: 2026 Feb 09
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