Implementation of a fully biodegradable and biomimetic epicardial patch providing synergic physico-chemical, mechanical and electrical cues for myocardial infarction therapy.

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Title: Implementation of a fully biodegradable and biomimetic epicardial patch providing synergic physico-chemical, mechanical and electrical cues for myocardial infarction therapy.
Authors: Cristallini C; Institute for Chemical and Physical Processes, CNR-IPCF, via Giuseppe Moruzzi 1, 56124, Pisa, Italy; Department of Civil and Industrial Engineering, DICI, University of Pisa, Largo Lucio Lazzarino, 56126, Pisa, Italy. Electronic address: caterina.cristallini@cnr.it., Rossin D; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, 10043, Orbassano, Italy. Electronic address: d.rossin@unito.it., Barbani N; Institute for Chemical and Physical Processes, CNR-IPCF, via Giuseppe Moruzzi 1, 56124, Pisa, Italy; Department of Civil and Industrial Engineering, DICI, University of Pisa, Largo Lucio Lazzarino, 56126, Pisa, Italy., Vanni R; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, 10043, Orbassano, Italy., Labardi M; Institute for Chemical and Physical Processes, CNR-IPCF, via Giuseppe Moruzzi 1, 56124, Pisa, Italy., Trouki C; Institute for Chemical and Physical Processes, CNR-IPCF, via Giuseppe Moruzzi 1, 56124, Pisa, Italy; Department of Pharmacy, University of Pisa, via Bonanno 6, 56126, Pisa, Italy., Burchielli S; Fondazione Monasterio, via Giuseppe Moruzzi 1, 56124, Pisa, Italy., Kusmic C; Clinical Physiology Institute, CNR-IFC, via Giuseppe Moruzzi 1, 56124, Pisa, Italy., Terlizzi D; Fondazione Monasterio, via Giuseppe Moruzzi 1, 56124, Pisa, Italy., Sergi F; Department of Civil and Industrial Engineering, DICI, University of Pisa, Largo Lucio Lazzarino, 56126, Pisa, Italy., Bulgheresi C; Department of Civil and Industrial Engineering, DICI, University of Pisa, Largo Lucio Lazzarino, 56126, Pisa, Italy., Rossino D; Institute for Chemical and Physical Processes, CNR-IPCF, via Giuseppe Moruzzi 1, 56124, Pisa, Italy; Department of Civil and Industrial Engineering, DICI, University of Pisa, Largo Lucio Lazzarino, 56126, Pisa, Italy., Fiorino E; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, 10043, Orbassano, Italy., Aubry M; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, 10043, Orbassano, Italy., Lo Iacono M; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, 10043, Orbassano, Italy., Perveen S; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, 10043, Orbassano, Italy., Scarpellino G; Department of Life Sciences and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123, Torino, Italy., Munaron L; Department of Life Sciences and Systems Biology, University of Turin, Via Accademia Albertina 13, 10123, Torino, Italy; Nanomaterials for Industry and Sustainability Inter-Departmental Centre (NIS), University of Turin, Italy., Amorim S; 3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-017, Barco, Guimarães, Portugal; ICVS/3B's-PT Government Associate Laboratory, Braga, Guimarães, Portugal., Pires RA; 3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-017, Barco, Guimarães, Portugal; ICVS/3B's-PT Government Associate Laboratory, Braga, Guimarães, Portugal., Reis RL; 3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-017, Barco, Guimarães, Portugal; ICVS/3B's-PT Government Associate Laboratory, Braga, Guimarães, Portugal., Rastaldo R; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, 10043, Orbassano, Italy., Giachino C; Department of Clinical and Biological Sciences, University of Turin, Regione Gonzole 10, 10043, Orbassano, Italy.
Source: Biomaterials advances [Biomater Adv] 2026 Feb; Vol. 179, pp. 214523. Date of Electronic Publication: 2025 Sep 24.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9918383886206676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2772-9508 (Electronic) Linking ISSN: 27729508 NLM ISO Abbreviation: Biomater Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2772-9508
DOI:10.1016/j.bioadv.2025.214523