View in EDS

High-Affinity, Structure-Validated and Selective Macrocyclic Peptide Tools for Chemical Biology Studies of Huntingtin.

Saved in:
Bibliographic Details
Title: High-Affinity, Structure-Validated and Selective Macrocyclic Peptide Tools for Chemical Biology Studies of Huntingtin.
Authors: Wolf E; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G1L7, Canada., Fanti R; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.; Department of Molecular Genetics, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada., Ikenoue T; Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan., Deme JC; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA., Balakrishnan S; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Keith BA; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Alteen MG; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Chandrasekaran R; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Yadav M; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G1L7, Canada., Bhajiawala R; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Ackloo S; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada., Feng J; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, Djavad Mowafaghian Centre for Brain Health, Edwin S. H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada., Pouladi MA; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, Djavad Mowafaghian Centre for Brain Health, Edwin S. H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada., Edwards AM; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.; Department of Molecular Genetics, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada., Wilson D; Department of Chemistry, York University, Toronto, ON M3J 1P3, Canada., Lea SM; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA., Suga H; Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan., Harding RJ; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto ON M5S 3M2, Canada.; Department of Pharmacology and Toxicology, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Aug 06. Date of Electronic Publication: 2025 Aug 06.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41030958
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: High-Affinity, Structure-Validated and Selective Macrocyclic Peptide Tools for Chemical Biology Studies of Huntingtin.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Wolf+E%22">Wolf E</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Fanti+R%22">Fanti R</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.; Department of Molecular Genetics, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Ikenoue+T%22">Ikenoue T</searchLink>; Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan.<br /><searchLink fieldCode="AU" term="%22Deme+JC%22">Deme JC</searchLink>; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.<br /><searchLink fieldCode="AU" term="%22Balakrishnan+S%22">Balakrishnan S</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Keith+BA%22">Keith BA</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Alteen+MG%22">Alteen MG</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Chandrasekaran+R%22">Chandrasekaran R</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Yadav+M%22">Yadav M</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Bhajiawala+R%22">Bhajiawala R</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Ackloo+S%22">Ackloo S</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.<br /><searchLink fieldCode="AU" term="%22Feng+J%22">Feng J</searchLink>; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, Djavad Mowafaghian Centre for Brain Health, Edwin S. H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Pouladi+MA%22">Pouladi MA</searchLink>; Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, Djavad Mowafaghian Centre for Brain Health, Edwin S. H. Leong Centre for Healthy Aging, Faculty of Medicine, University of British Columbia, British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Edwards+AM%22">Edwards AM</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.; Department of Molecular Genetics, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Wilson+D%22">Wilson D</searchLink>; Department of Chemistry, York University, Toronto, ON M3J 1P3, Canada.<br /><searchLink fieldCode="AU" term="%22Lea+SM%22">Lea SM</searchLink>; Center for Structural Biology, Center for Cancer Research, National Cancer Institute, Frederick, MD, USA.<br /><searchLink fieldCode="AU" term="%22Suga+H%22">Suga H</searchLink>; Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan.<br /><searchLink fieldCode="AU" term="%22Harding+RJ%22">Harding RJ</searchLink>; Structural Genomics Consortium, University of Toronto, Toronto, ON M5G 1L7, Canada.; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto ON M5S 3M2, Canada.; Department of Pharmacology and Toxicology, Faculty of Medicine, University of Toronto, Toronto, ON M5S 1A8, Canada.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2025 Aug 06. <i>Date of Electronic Publication: </i>2025 Aug 06.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Preprint
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41030958
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1101/2025.08.06.668955
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: High-Affinity, Structure-Validated and Selective Macrocyclic Peptide Tools for Chemical Biology Studies of Huntingtin.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Wolf E
      – PersonEntity:
          Name:
            NameFull: Fanti R
      – PersonEntity:
          Name:
            NameFull: Ikenoue T
      – PersonEntity:
          Name:
            NameFull: Deme JC
      – PersonEntity:
          Name:
            NameFull: Balakrishnan S
      – PersonEntity:
          Name:
            NameFull: Keith BA
      – PersonEntity:
          Name:
            NameFull: Alteen MG
      – PersonEntity:
          Name:
            NameFull: Chandrasekaran R
      – PersonEntity:
          Name:
            NameFull: Yadav M
      – PersonEntity:
          Name:
            NameFull: Bhajiawala R
      – PersonEntity:
          Name:
            NameFull: Ackloo S
      – PersonEntity:
          Name:
            NameFull: Feng J
      – PersonEntity:
          Name:
            NameFull: Pouladi MA
      – PersonEntity:
          Name:
            NameFull: Edwards AM
      – PersonEntity:
          Name:
            NameFull: Wilson D
      – PersonEntity:
          Name:
            NameFull: Lea SM
      – PersonEntity:
          Name:
            NameFull: Suga H
      – PersonEntity:
          Name:
            NameFull: Harding RJ
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 06
              M: 08
              Text: 2025 Aug 06
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2692-8205
          Titles:
            – TitleFull: BioRxiv : the preprint server for biology
              Type: main
ResultId 1