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A topical nociceutical formulation ameliorates chemotherapy-induced peripheral neuropathy: a pilot randomized clinical study.

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Title: A topical nociceutical formulation ameliorates chemotherapy-induced peripheral neuropathy: a pilot randomized clinical study.
Authors: Servitja S; Servicio de Oncología Médica, Hospital del Mar, 08003, Barcelona, Spain. sservitja@psmar.cat., Castro-Henriques M; Servicio de Oncología Médica, Hospital del Mar, 08003, Barcelona, Spain., Álvarez-Busto I; Servicio de Oncología Médica, Hospital Universitario Miguel Servet, 50009, Saragossa, Spain.; Aragon Health Research Institute (IIS Aragón), Saragossa, Spain., Díez-Franco C; Servicio de Oncología Médica, Hospital Universitario Miguel Servet, 50009, Saragossa, Spain.; Aragon Health Research Institute (IIS Aragón), Saragossa, Spain., Medina-Castillo A; Servicio de Oncología Médica, Hospital Universitario Miguel Servet, 50009, Saragossa, Spain.; Aragon Health Research Institute (IIS Aragón), Saragossa, Spain., Algarra-García MA; Servicio de Oncología Médica, Hospital Marina Baixa, 03570, Villajoyosa, Alicante, Spain., López-Miranda E; Servicio de Oncología Médica, Hospital Universitario Ramon y Cajal, 28034, Madrid, Spain., Lario-Martínez M; Servicio de Oncología Médica, Hospital Universitario Ramon y Cajal, 28034, Madrid, Spain., Luengo-Alcázar MI; Servicio de Oncología Médica, Hospital General Universitario Santa Lucía, 30202, Cartagena, Murcia, Spain.; Hospital General Universitario de Elda, 03600, Elda, Alicante, Spain., Borregón M; Servicio de Oncología Médica, Hospital General Universitario de Elche, 03202, Elche , Alicante, Spain., Davó A; Servicio de Oncología Médica, Hospital General Universitario de Elche, 03202, Elche , Alicante, Spain., Gasull-Delgado A; Servicio de Oncología Médica, Hospital Universitari Sagrat Cor, 08029, Barcelona, Spain., Roque-García S; Servicio de Oncología Médica, Hospital Universitari Sagrat Cor, 08029, Barcelona, Spain., Gonzaga-López A; Servicio de Oncología Médica, Hospital General Universitario de Elche, 03202, Elche , Alicante, Spain., Poveda-Ferriols JM; CHU St-Pierre-UMC St-Pieter, 1000, Brussels, Belgium., Pascal S; CHU St-Pierre-UMC St-Pieter, 1000, Brussels, Belgium., Mitroi-Marinescu AM; Scientific Park, Prospera Biotech, University Miguel Hernández, 03202, Elche, SL, Spain., García-Escolano M; Scientific Park, Prospera Biotech, University Miguel Hernández, 03202, Elche, SL, Spain., Fernández-Carvajal A; Instituto de Investigación, Desarrollo E Innovación en Biotecnología Sanitaria de Elche (IDiBE), Universidad Miguel Hernández, 03202, Elche, Spain., Ferrándiz-Huertas C; Scientific Park, Prospera Biotech, University Miguel Hernández, 03202, Elche, SL, Spain., Ferrer-Montiel A; Instituto de Investigación, Desarrollo E Innovación en Biotecnología Sanitaria de Elche (IDiBE), Universidad Miguel Hernández, 03202, Elche, Spain. aferrer@umh.es.
Source: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2026 Mar; Vol. 28 (3), pp. 1040-1048. Date of Electronic Publication: 2025 Oct 01.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Springer Italia Country of Publication: Italy NLM ID: 101247119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-3055 (Electronic) Linking ISSN: 1699048X NLM ISO Abbreviation: Clin Transl Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A topical nociceutical formulation ameliorates chemotherapy-induced peripheral neuropathy: a pilot randomized clinical study.
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  Data: <searchLink fieldCode="AU" term="%22Servitja+S%22">Servitja S</searchLink>; Servicio de Oncología Médica, Hospital del Mar, 08003, Barcelona, Spain. sservitja@psmar.cat.<br /><searchLink fieldCode="AU" term="%22Castro-Henriques+M%22">Castro-Henriques M</searchLink>; Servicio de Oncología Médica, Hospital del Mar, 08003, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Álvarez-Busto+I%22">Álvarez-Busto I</searchLink>; Servicio de Oncología Médica, Hospital Universitario Miguel Servet, 50009, Saragossa, Spain.; Aragon Health Research Institute (IIS Aragón), Saragossa, Spain.<br /><searchLink fieldCode="AU" term="%22Díez-Franco+C%22">Díez-Franco C</searchLink>; Servicio de Oncología Médica, Hospital Universitario Miguel Servet, 50009, Saragossa, Spain.; Aragon Health Research Institute (IIS Aragón), Saragossa, Spain.<br /><searchLink fieldCode="AU" term="%22Medina-Castillo+A%22">Medina-Castillo A</searchLink>; Servicio de Oncología Médica, Hospital Universitario Miguel Servet, 50009, Saragossa, Spain.; Aragon Health Research Institute (IIS Aragón), Saragossa, Spain.<br /><searchLink fieldCode="AU" term="%22Algarra-García+MA%22">Algarra-García MA</searchLink>; Servicio de Oncología Médica, Hospital Marina Baixa, 03570, Villajoyosa, Alicante, Spain.<br /><searchLink fieldCode="AU" term="%22López-Miranda+E%22">López-Miranda E</searchLink>; Servicio de Oncología Médica, Hospital Universitario Ramon y Cajal, 28034, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Lario-Martínez+M%22">Lario-Martínez M</searchLink>; Servicio de Oncología Médica, Hospital Universitario Ramon y Cajal, 28034, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Luengo-Alcázar+MI%22">Luengo-Alcázar MI</searchLink>; Servicio de Oncología Médica, Hospital General Universitario Santa Lucía, 30202, Cartagena, Murcia, Spain.; Hospital General Universitario de Elda, 03600, Elda, Alicante, Spain.<br /><searchLink fieldCode="AU" term="%22Borregón+M%22">Borregón M</searchLink>; Servicio de Oncología Médica, Hospital General Universitario de Elche, 03202, Elche , Alicante, Spain.<br /><searchLink fieldCode="AU" term="%22Davó+A%22">Davó A</searchLink>; Servicio de Oncología Médica, Hospital General Universitario de Elche, 03202, Elche , Alicante, Spain.<br /><searchLink fieldCode="AU" term="%22Gasull-Delgado+A%22">Gasull-Delgado A</searchLink>; Servicio de Oncología Médica, Hospital Universitari Sagrat Cor, 08029, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Roque-García+S%22">Roque-García S</searchLink>; Servicio de Oncología Médica, Hospital Universitari Sagrat Cor, 08029, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Gonzaga-López+A%22">Gonzaga-López A</searchLink>; Servicio de Oncología Médica, Hospital General Universitario de Elche, 03202, Elche , Alicante, Spain.<br /><searchLink fieldCode="AU" term="%22Poveda-Ferriols+JM%22">Poveda-Ferriols JM</searchLink>; CHU St-Pierre-UMC St-Pieter, 1000, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Pascal+S%22">Pascal S</searchLink>; CHU St-Pierre-UMC St-Pieter, 1000, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Mitroi-Marinescu+AM%22">Mitroi-Marinescu AM</searchLink>; Scientific Park, Prospera Biotech, University Miguel Hernández, 03202, Elche, SL, Spain.<br /><searchLink fieldCode="AU" term="%22García-Escolano+M%22">García-Escolano M</searchLink>; Scientific Park, Prospera Biotech, University Miguel Hernández, 03202, Elche, SL, Spain.<br /><searchLink fieldCode="AU" term="%22Fernández-Carvajal+A%22">Fernández-Carvajal A</searchLink>; Instituto de Investigación, Desarrollo E Innovación en Biotecnología Sanitaria de Elche (IDiBE), Universidad Miguel Hernández, 03202, Elche, Spain.<br /><searchLink fieldCode="AU" term="%22Ferrándiz-Huertas+C%22">Ferrándiz-Huertas C</searchLink>; Scientific Park, Prospera Biotech, University Miguel Hernández, 03202, Elche, SL, Spain.<br /><searchLink fieldCode="AU" term="%22Ferrer-Montiel+A%22">Ferrer-Montiel A</searchLink>; Instituto de Investigación, Desarrollo E Innovación en Biotecnología Sanitaria de Elche (IDiBE), Universidad Miguel Hernández, 03202, Elche, Spain. aferrer@umh.es.
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