SCH79797, an Antiplatelet Agent, Alleviates Restenosis by Inducing Apoptosis via p53-Mediated Mitochondrial Depolarization and Inhibiting Thrombus Formation after Angioplasty.

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Title: SCH79797, an Antiplatelet Agent, Alleviates Restenosis by Inducing Apoptosis via p53-Mediated Mitochondrial Depolarization and Inhibiting Thrombus Formation after Angioplasty.
Authors: Yen TL; Department of Medical Research, Cathay General Hospital, 280 Renai Rd. Sec.4, Taipei City 10630, Taiwan.; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, No. 250, Wu Hsing St., Taipei 110, Taiwan., Hong KJ; Department of Medical Research, Cathay General Hospital, 280 Renai Rd. Sec.4, Taipei City 10630, Taiwan., Jan JS; Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, No. 250, Wu Hsing St., Taipei 110, Taiwan., Chen YL; Division of Cardiac Electrophysiology, Department of Cardiovascular Center, Cathay General Hospital, 280 Renai Rd. Sec.4, Taipei City 10630, Taiwan.; Division of Cardiac Electrophysiology, Department of Cardiovascular Center, Cathay General Hospital, 280 Renai Rd. Sec.4, Taipei City 10630, Taiwan., Chou PC; Division of Interventional Cardiology, Department of Cardiovascular Center, Cathay General Hospital, 280 Renai Rd. Sec.4, Taipei City 10630, Taiwan., Chen CY; Division of General Cardiology, Department of Cardiovascular Center, Cathay General Hospital, 280 Renai Rd. Sec.4, Taipei City 10630, Taiwan., Ko WC; Division of Cardiac Electrophysiology, Department of Cardiovascular Center, Cathay General Hospital, 280 Renai Rd. Sec.4, Taipei City 10630, Taiwan.; School of Medicine, College of Medicine, Fu Jen Catholic University, 510, Zhongzheng Rd., Xinzhuang Dist., New Taipei City 242062, Taiwan.
Source: Current molecular medicine [Curr Mol Med] 2025 Oct 01. Date of Electronic Publication: 2025 Oct 01.
Publication Type: Journal Article
Journal Info: Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101093076 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-5666 (Electronic) Linking ISSN: 15665240 NLM ISO Abbreviation: Curr Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1875-5666
DOI:10.2174/0115665240375398250916093346