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Determining the optimal approach to identify osimertinib resistance; the first line osimertinib cohort of the OSIRIS study.

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Title: Determining the optimal approach to identify osimertinib resistance; the first line osimertinib cohort of the OSIRIS study.
Authors: van der Wel JWT; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Ernst SM; Department of Pulmonary Diseases, Erasmus University Medical Center Cancer Institute, Rotterdam, the Netherlands., Jebbink M; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands., van den Broek D; Department of Laboratory Medicine, Netherlands Cancer Institute, Amsterdam, the Netherlands., Badrising SK; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Steinbusch LC; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Pulmonary Diseases, Leiden University Medical Center, Leiden, the Netherlands., Ruiter G; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Theelen WSME; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands., van Veggel BAMH; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Pulmonary Diseases, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands., Smit J; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Dingemans AM; Department of Pulmonary Diseases, Erasmus University Medical Center Cancer Institute, Rotterdam, the Netherlands., Paats MS; Department of Pulmonary Diseases, Erasmus University Medical Center Cancer Institute, Rotterdam, the Netherlands., Dubbink HJ; Department of Pathology, Erasmus University Medical Center, Rotterdam, the Netherlands., Hashemi SMS; Department of Pulmonary Medicine, Amsterdam UMC, Amsterdam, the Netherlands., Radonic T; Department of Pathology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam, the Netherlands., Cohen D; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands., van der Wekken AJ; Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Ter Elst A; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Timens W; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Hendriks LE; Department of Pulmonary Diseases, GROW - Research Institute for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, the Netherlands., Speel EJM; Department of Pathology, Erasmus University Medical Center, Rotterdam, the Netherlands; Department of Pathology, GROW - Research Institute for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, the Netherlands., Disselhorst MMJ; Department of Pulmonary Diseases, Northwest Clinics, Alkmaar, the Netherlands., Welling A; Department of Pulmonary Diseases, Northwest Clinics, Alkmaar, the Netherlands., van der Meer F; Department of Pulmonary Diseases, Diakonessenhuis, Utrecht, the Netherlands., Bosch LJW; Department of Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Monkhorst K; Department of Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Boelens MC; Department of Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands., Smit EF; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Pulmonary Diseases, Leiden University Medical Center, Leiden, the Netherlands., de Langen AJ; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands. Electronic address: j.d.langen@nki.nl.
Source: Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2025 Nov; Vol. 209, pp. 108783. Date of Electronic Publication: 2025 Sep 28.
Publication Type: Clinical Trial; Journal Article; Multicenter Study
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8800805 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8332 (Electronic) Linking ISSN: 01695002 NLM ISO Abbreviation: Lung Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Determining the optimal approach to identify osimertinib resistance; the first line osimertinib cohort of the OSIRIS study.
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  Data: <searchLink fieldCode="AU" term="%22van+der+Wel+JWT%22">van der Wel JWT</searchLink>; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Ernst+SM%22">Ernst SM</searchLink>; Department of Pulmonary Diseases, Erasmus University Medical Center Cancer Institute, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Jebbink+M%22">Jebbink M</searchLink>; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Broek+D%22">van den Broek D</searchLink>; Department of Laboratory Medicine, Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Badrising+SK%22">Badrising SK</searchLink>; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Steinbusch+LC%22">Steinbusch LC</searchLink>; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Pulmonary Diseases, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Ruiter+G%22">Ruiter G</searchLink>; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Theelen+WSME%22">Theelen WSME</searchLink>; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Veggel+BAMH%22">van Veggel BAMH</searchLink>; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Pulmonary Diseases, Jeroen Bosch Hospital, 's-Hertogenbosch, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Smit+J%22">Smit J</searchLink>; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Dingemans+AM%22">Dingemans AM</searchLink>; Department of Pulmonary Diseases, Erasmus University Medical Center Cancer Institute, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Paats+MS%22">Paats MS</searchLink>; Department of Pulmonary Diseases, Erasmus University Medical Center Cancer Institute, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Dubbink+HJ%22">Dubbink HJ</searchLink>; Department of Pathology, Erasmus University Medical Center, Rotterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Hashemi+SMS%22">Hashemi SMS</searchLink>; Department of Pulmonary Medicine, Amsterdam UMC, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Radonic+T%22">Radonic T</searchLink>; Department of Pathology, Amsterdam UMC, Cancer Center Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Cohen+D%22">Cohen D</searchLink>; Department of Pathology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Wekken+AJ%22">van der Wekken AJ</searchLink>; Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Ter+Elst+A%22">Ter Elst A</searchLink>; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Timens+W%22">Timens W</searchLink>; Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Hendriks+LE%22">Hendriks LE</searchLink>; Department of Pulmonary Diseases, GROW - Research Institute for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Speel+EJM%22">Speel EJM</searchLink>; Department of Pathology, Erasmus University Medical Center, Rotterdam, the Netherlands; Department of Pathology, GROW - Research Institute for Oncology and Reproduction, Maastricht University Medical Center, Maastricht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Disselhorst+MMJ%22">Disselhorst MMJ</searchLink>; Department of Pulmonary Diseases, Northwest Clinics, Alkmaar, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Welling+A%22">Welling A</searchLink>; Department of Pulmonary Diseases, Northwest Clinics, Alkmaar, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Meer+F%22">van der Meer F</searchLink>; Department of Pulmonary Diseases, Diakonessenhuis, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bosch+LJW%22">Bosch LJW</searchLink>; Department of Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Monkhorst+K%22">Monkhorst K</searchLink>; Department of Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Boelens+MC%22">Boelens MC</searchLink>; Department of Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Smit+EF%22">Smit EF</searchLink>; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands; Department of Pulmonary Diseases, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Langen+AJ%22">de Langen AJ</searchLink>; Department of Thoracic Oncology, Netherlands Cancer Institute, Amsterdam, the Netherlands. Electronic address: j.d.langen@nki.nl.
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  Data: <searchLink fieldCode="JN" term="%228800805%22">Lung cancer (Amsterdam, Netherlands)</searchLink> [Lung Cancer] 2025 Nov; Vol. 209, pp. 108783. <i>Date of Electronic Publication: </i>2025 Sep 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Scientific+Publishers%22">Elsevier Scientific Publishers </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>8800805 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-8332 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201695002%22">01695002 </searchLink><i>NLM ISO Abbreviation: </i>Lung Cancer <i>Subsets: </i>MEDLINE
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