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Transcriptomic and proteomic profiling reveal immune and metabolic dysregulation in the colonic mucosa of people living with HIV with incomplete immune recovery.

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Title: Transcriptomic and proteomic profiling reveal immune and metabolic dysregulation in the colonic mucosa of people living with HIV with incomplete immune recovery.
Authors: Kaarbø M; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Yang M; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Meyer-Myklestad MH; Department of Microbiology, Oslo University Hospital, Oslo, Norway.; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway., Sundaram AYM; Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway., de Sousa MML; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Sharma A; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Proteomics and Modomics Experimental Core Facility at Norwegian University of Science and Technology, and the Central Norway Regional Health Authority, Trondheim, Norway., Medhus AW; Department of Gastroenterology, Oslo University Hospital, Oslo, Norway.; Institute for Clinical Medicine, University of Oslo, Oslo, Norway., Dyrhol-Riise AM; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway.; Institute for Clinical Medicine, University of Oslo, Oslo, Norway., Kvale D; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway.; Institute for Clinical Medicine, University of Oslo, Oslo, Norway., Hov JR; Institute for Clinical Medicine, University of Oslo, Oslo, Norway.; Norwegian PSC Research Centre and Section of Gastroenterology, Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Oslo, Norway., Aukrust P; Institute for Clinical Medicine, University of Oslo, Oslo, Norway.; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Oslo, Norway., Bjørås M; Department of Microbiology, Oslo University Hospital, Oslo, Norway.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Centre for Embryology and Healthy Development, University of Oslo and Oslo University Hospital, Oslo, Norway., Reikvam DH; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway.; Institute for Clinical Medicine, University of Oslo, Oslo, Norway.
Source: Frontiers in immunology [Front Immunol] 2025 Sep 17; Vol. 16, pp. 1635523. Date of Electronic Publication: 2025 Sep 17 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
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  Data: Transcriptomic and proteomic profiling reveal immune and metabolic dysregulation in the colonic mucosa of people living with HIV with incomplete immune recovery.
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  Data: <searchLink fieldCode="AU" term="%22Kaarbø+M%22">Kaarbø M</searchLink>; Department of Microbiology, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Yang+M%22">Yang M</searchLink>; Department of Microbiology, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Meyer-Myklestad+MH%22">Meyer-Myklestad MH</searchLink>; Department of Microbiology, Oslo University Hospital, Oslo, Norway.; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Sundaram+AYM%22">Sundaram AYM</searchLink>; Department of Medical Genetics, Oslo University Hospital and University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22de+Sousa+MML%22">de Sousa MML</searchLink>; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Sharma+A%22">Sharma A</searchLink>; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Proteomics and Modomics Experimental Core Facility at Norwegian University of Science and Technology, and the Central Norway Regional Health Authority, Trondheim, Norway.<br /><searchLink fieldCode="AU" term="%22Medhus+AW%22">Medhus AW</searchLink>; Department of Gastroenterology, Oslo University Hospital, Oslo, Norway.; Institute for Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Dyrhol-Riise+AM%22">Dyrhol-Riise AM</searchLink>; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway.; Institute for Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Kvale+D%22">Kvale D</searchLink>; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway.; Institute for Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Hov+JR%22">Hov JR</searchLink>; Institute for Clinical Medicine, University of Oslo, Oslo, Norway.; Norwegian PSC Research Centre and Section of Gastroenterology, Department of Transplantation Medicine, Oslo University Hospital, Oslo, Norway.; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Aukrust+P%22">Aukrust P</searchLink>; Institute for Clinical Medicine, University of Oslo, Oslo, Norway.; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Bjørås+M%22">Bjørås M</searchLink>; Department of Microbiology, Oslo University Hospital, Oslo, Norway.; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Centre for Embryology and Healthy Development, University of Oslo and Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Reikvam+DH%22">Reikvam DH</searchLink>; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway.; Institute for Clinical Medicine, University of Oslo, Oslo, Norway.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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