From Diagnosis to Disease Staging: Multisite Validation of Cerebrospinal Fluid Molecular Tests in Multiple Sclerosis.

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Title: From Diagnosis to Disease Staging: Multisite Validation of Cerebrospinal Fluid Molecular Tests in Multiple Sclerosis.
Authors: Ghezzi L; Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.; IRCCS Foundation, Ca'Granda Ospedale Maggiore Policlinico, Milan, Italy., Kosa P; Neuroimmunological Diseases Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Greenwood M; Department of Mathematical Sciences, Montana State University, Bozeman, MT, USA., Alvarez E; Department of Neurology, Rocky Mountain Multiple Sclerosis Center at the University of Colorado, Aurora, CO, USA., Freedman CL; University of Ottawa, Department of Medicine and the Ottawa Hospital Research Institute, Ottawa, ON, Canada., Cross AH; Department of Neurology, Washington University School of Medicine, St Louis, MI, USA., Pace F; Department of Neurology, Washington University School of Medicine, St Louis, MI, USA., Freedman MS; University of Ottawa, Department of Medicine and the Ottawa Hospital Research Institute, Ottawa, ON, Canada., Kocot J; Neuroimmunological Diseases Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Piccio L; Charles Perkins Centre and Brain and Mind Centre, Neuroscience, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia., Bielekova B; Neuroimmunological Diseases Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Source: Annals of neurology [Ann Neurol] 2026 Feb; Vol. 99 (2), pp. 328-340. Date of Electronic Publication: 2025 Oct 03.
Publication Type: Journal Article; Multicenter Study; Validation Study
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7707449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-8249 (Electronic) Linking ISSN: 03645134 NLM ISO Abbreviation: Ann Neurol Subsets: MEDLINE
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  Data: From Diagnosis to Disease Staging: Multisite Validation of Cerebrospinal Fluid Molecular Tests in Multiple Sclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Ghezzi+L%22">Ghezzi L</searchLink>; Department of Biomedical, Surgical and Dental Sciences, University of Milan, Milan, Italy.; IRCCS Foundation, Ca'Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Kosa+P%22">Kosa P</searchLink>; Neuroimmunological Diseases Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Greenwood+M%22">Greenwood M</searchLink>; Department of Mathematical Sciences, Montana State University, Bozeman, MT, USA.<br /><searchLink fieldCode="AU" term="%22Alvarez+E%22">Alvarez E</searchLink>; Department of Neurology, Rocky Mountain Multiple Sclerosis Center at the University of Colorado, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Freedman+CL%22">Freedman CL</searchLink>; University of Ottawa, Department of Medicine and the Ottawa Hospital Research Institute, Ottawa, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Cross+AH%22">Cross AH</searchLink>; Department of Neurology, Washington University School of Medicine, St Louis, MI, USA.<br /><searchLink fieldCode="AU" term="%22Pace+F%22">Pace F</searchLink>; Department of Neurology, Washington University School of Medicine, St Louis, MI, USA.<br /><searchLink fieldCode="AU" term="%22Freedman+MS%22">Freedman MS</searchLink>; University of Ottawa, Department of Medicine and the Ottawa Hospital Research Institute, Ottawa, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Kocot+J%22">Kocot J</searchLink>; Neuroimmunological Diseases Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Piccio+L%22">Piccio L</searchLink>; Charles Perkins Centre and Brain and Mind Centre, Neuroscience, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Bielekova+B%22">Bielekova B</searchLink>; Neuroimmunological Diseases Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
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  Data: <searchLink fieldCode="JN" term="%227707449%22">Annals of neurology</searchLink> [Ann Neurol] 2026 Feb; Vol. 99 (2), pp. 328-340. <i>Date of Electronic Publication: </i>2025 Oct 03.
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        Value: 10.1002/ana.78047
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      – TitleFull: From Diagnosis to Disease Staging: Multisite Validation of Cerebrospinal Fluid Molecular Tests in Multiple Sclerosis.
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              Text: 2026 Feb
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