Germline Pathogenic Variants in MUTYH Are Associated With Inferior Survival After Hematopoietic Cell Transplantation in Patients With Hematologic Malignancies or Disorders.

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Title: Germline Pathogenic Variants in MUTYH Are Associated With Inferior Survival After Hematopoietic Cell Transplantation in Patients With Hematologic Malignancies or Disorders.
Authors: Rafati M; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Wang Y; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Koppayi AL; Robert H. Lurie Comprehensive Cancer Center, And Northwestern University, Illinois, USA., Savage SA; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Godley LA; Robert H. Lurie Comprehensive Cancer Center, And Northwestern University, Illinois, USA., Williams KM; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University, Atlanta, Georgia, USA., Porter C; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University, Atlanta, Georgia, USA., Jones K; Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.; Leidos Biomedical Research, Inc. Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA., Hicks B; Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.; Leidos Biomedical Research, Inc. Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA., Spellman SR; CIBMTR (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, Minnesota, USA., He M; CIBMTR (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, Minnesota, USA., Atshan R; CIBMTR (Center for International Blood and Marrow Transplant Research), Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Iwuagwu C; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA., Bolon YT; CIBMTR (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, Minnesota, USA., Arrieta-Bolaños E; Institute for Experimental Cellular Therapy, University Hospital Essen, Essen, Germany.; German Cancer Consortium (DKTK), partner Site Essen/Düsseldorf, Heidelberg, Germany., Saultz JN; Division of Hematology/Medical Oncology, Oregon Health and Science University, Portland, Oregon, USA., Benjamin CL; Division of Transplantation and Cellular Therapy, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA., Lee SJ; CIBMTR (Center for International Blood and Marrow Transplant Research), Medical College of Wisconsin, Milwaukee, Wisconsin, USA.; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA, USA., Saber W; CIBMTR (Center for International Blood and Marrow Transplant Research), Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Gadalla SM; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
Source: American journal of hematology [Am J Hematol] 2025 Dec; Vol. 100 (12), pp. 2442-2447. Date of Electronic Publication: 2025 Oct 03.
Publication Type: Letter
Journal Info: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 7610369 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-8652 (Electronic) Linking ISSN: 03618609 NLM ISO Abbreviation: Am J Hematol Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: Germline Pathogenic Variants in MUTYH Are Associated With Inferior Survival After Hematopoietic Cell Transplantation in Patients With Hematologic Malignancies or Disorders.
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  Data: <searchLink fieldCode="AU" term="%22Rafati+M%22">Rafati M</searchLink>; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Koppayi+AL%22">Koppayi AL</searchLink>; Robert H. Lurie Comprehensive Cancer Center, And Northwestern University, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Savage+SA%22">Savage SA</searchLink>; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Godley+LA%22">Godley LA</searchLink>; Robert H. Lurie Comprehensive Cancer Center, And Northwestern University, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Williams+KM%22">Williams KM</searchLink>; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Porter+C%22">Porter C</searchLink>; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Jones+K%22">Jones K</searchLink>; Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.; Leidos Biomedical Research, Inc. Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Hicks+B%22">Hicks B</searchLink>; Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.; Leidos Biomedical Research, Inc. Frederick National Laboratory for Cancer Research, Frederick, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Spellman+SR%22">Spellman SR</searchLink>; CIBMTR (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22He+M%22">He M</searchLink>; CIBMTR (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Atshan+R%22">Atshan R</searchLink>; CIBMTR (Center for International Blood and Marrow Transplant Research), Medical College of Wisconsin, Milwaukee, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Iwuagwu+C%22">Iwuagwu C</searchLink>; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Bolon+YT%22">Bolon YT</searchLink>; CIBMTR (Center for International Blood and Marrow Transplant Research), NMDP, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Arrieta-Bolaños+E%22">Arrieta-Bolaños E</searchLink>; Institute for Experimental Cellular Therapy, University Hospital Essen, Essen, Germany.; German Cancer Consortium (DKTK), partner Site Essen/Düsseldorf, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Saultz+JN%22">Saultz JN</searchLink>; Division of Hematology/Medical Oncology, Oregon Health and Science University, Portland, Oregon, USA.<br /><searchLink fieldCode="AU" term="%22Benjamin+CL%22">Benjamin CL</searchLink>; Division of Transplantation and Cellular Therapy, Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Lee+SJ%22">Lee SJ</searchLink>; CIBMTR (Center for International Blood and Marrow Transplant Research), Medical College of Wisconsin, Milwaukee, Wisconsin, USA.; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Saber+W%22">Saber W</searchLink>; CIBMTR (Center for International Blood and Marrow Transplant Research), Medical College of Wisconsin, Milwaukee, Wisconsin, USA.<br /><searchLink fieldCode="AU" term="%22Gadalla+SM%22">Gadalla SM</searchLink>; Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.
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  Data: <searchLink fieldCode="JN" term="%227610369%22">American journal of hematology</searchLink> [Am J Hematol] 2025 Dec; Vol. 100 (12), pp. 2442-2447. <i>Date of Electronic Publication: </i>2025 Oct 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7610369 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1096-8652 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203618609%22">03618609 </searchLink><i>NLM ISO Abbreviation: </i>Am J Hematol <i>Subsets: </i>MEDLINE; In Process
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