A safe, T cell-inducing heterologous vaccine against elephant endotheliotropic herpesvirus in a proof-of-concept study.

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Title: A safe, T cell-inducing heterologous vaccine against elephant endotheliotropic herpesvirus in a proof-of-concept study.
Authors: Maehr T; Department of Comparative Biomedical Sciences, School of Veterinary Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom. tanja.maehr@apha.gov.uk.; North of England Zoological Society, Chester Zoo, Upton by Chester, United Kingdom. tanja.maehr@apha.gov.uk.; Virology Department, Animal and Plant Health Agency (APHA) Weybridge, Addlestone, United Kingdom. tanja.maehr@apha.gov.uk., Lopez J; North of England Zoological Society, Chester Zoo, Upton by Chester, United Kingdom., Drake G; North of England Zoological Society, Chester Zoo, Upton by Chester, United Kingdom., Ferreira FM; Cellular, Genetic, and Molecular Nephrology Laboratory (LIM-29), Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil., Fraser R; North of England Zoological Society, Chester Zoo, Upton by Chester, United Kingdom., Mckown R; North of England Zoological Society, Chester Zoo, Upton by Chester, United Kingdom., Kailath R; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Morris S; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Chambers A; Oxford Expression Technologies Ltd, Bioinnovation Hub, Oxford, United Kingdom., Graves LP; Oxford Expression Technologies Ltd, Bioinnovation Hub, Oxford, United Kingdom., Walker SL; North of England Zoological Society, Chester Zoo, Upton by Chester, United Kingdom., Dastjerdi A; Virology Department, Animal and Plant Health Agency (APHA) Weybridge, Addlestone, United Kingdom., Edwards KL; North of England Zoological Society, Chester Zoo, Upton by Chester, United Kingdom., Nakaya HI; Hospital Israelita Albert Einstein, São Paulo, Brazil.; Instituto Pasteur de São Paulo, São Paulo, Brazil.; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, Brazil., Steinbach F; Department of Comparative Biomedical Sciences, School of Veterinary Medicine, Faculty of Health and Medical Sciences, University of Surrey, Guildford, United Kingdom. f.steinbach@surrey.ac.uk.; Virology Department, Animal and Plant Health Agency (APHA) Weybridge, Addlestone, United Kingdom. f.steinbach@surrey.ac.uk.
Source: Nature communications [Nat Commun] 2025 Oct 03; Vol. 16 (1), pp. 8374. Date of Electronic Publication: 2025 Oct 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-64004-x