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SFPQ-TFE3 reciprocally regulates mTORC1 and induces lineage plasticity in a mouse model of renal tumorigenesis.

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Title: SFPQ-TFE3 reciprocally regulates mTORC1 and induces lineage plasticity in a mouse model of renal tumorigenesis.
Authors: Asrani K; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. kasrani1@jhmi.edu.; Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. kasrani1@jhmi.edu., Amaral A; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Woo J; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Abadchi SN; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Vidotto T; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Imada E; Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Skaist A; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Feng K; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Liu HB; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Kasbe M; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Satou Y; Division of Genomics and Transcriptomics, Kumamoto University, Kumamoto, Japan., Baba M; Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Oike Y; Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Outeda P; University of Maryland, School of Medicine, Baltimore, MD, USA., Watnick T; University of Maryland, School of Medicine, Baltimore, MD, USA., Rosenberg AZ; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Schmidt LS; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.; Basic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA., Linehan WM; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Argani P; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Lotan TL; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. tlotan1@jhmi.edu.; Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. tlotan1@jhmi.edu.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. tlotan1@jhmi.edu.
Source: Nature communications [Nat Commun] 2025 Oct 03; Vol. 16 (1), pp. 8822. Date of Electronic Publication: 2025 Oct 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: SFPQ-TFE3 reciprocally regulates mTORC1 and induces lineage plasticity in a mouse model of renal tumorigenesis.
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  Data: <searchLink fieldCode="AU" term="%22Asrani+K%22">Asrani K</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. kasrani1@jhmi.edu.; Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. kasrani1@jhmi.edu.<br /><searchLink fieldCode="AU" term="%22Amaral+A%22">Amaral A</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Woo+J%22">Woo J</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Abadchi+SN%22">Abadchi SN</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Vidotto+T%22">Vidotto T</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Imada+E%22">Imada E</searchLink>; Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Skaist+A%22">Skaist A</searchLink>; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Feng+K%22">Feng K</searchLink>; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Liu+HB%22">Liu HB</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kasbe+M%22">Kasbe M</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Satou+Y%22">Satou Y</searchLink>; Division of Genomics and Transcriptomics, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Baba+M%22">Baba M</searchLink>; Department of Urology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Oike+Y%22">Oike Y</searchLink>; Department of Molecular Genetics, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Outeda+P%22">Outeda P</searchLink>; University of Maryland, School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Watnick+T%22">Watnick T</searchLink>; University of Maryland, School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Rosenberg+AZ%22">Rosenberg AZ</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Schmidt+LS%22">Schmidt LS</searchLink>; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.; Basic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.<br /><searchLink fieldCode="AU" term="%22Linehan+WM%22">Linehan WM</searchLink>; Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Argani+P%22">Argani P</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lotan+TL%22">Lotan TL</searchLink>; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. tlotan1@jhmi.edu.; Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. tlotan1@jhmi.edu.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. tlotan1@jhmi.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Oct 03; Vol. 16 (1), pp. 8822. <i>Date of Electronic Publication: </i>2025 Oct 03.
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