Development of a real-time polymerase chain reaction (RT-PCR) assay for simultaneous detection of Helicobacter pylori infection and genetic mutations associated with clarithromycin resistance: A single-center, cross-sectional study from Singapore.
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| Title: | Development of a real-time polymerase chain reaction (RT-PCR) assay for simultaneous detection of Helicobacter pylori infection and genetic mutations associated with clarithromycin resistance: A single-center, cross-sectional study from Singapore. |
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| Authors: | Jiang B; Department of Laboratory Medicine, Changi General Hospital, 2 Simei Street 3, Singapore 529889, Singapore. Electronic address: jiang_boran@cgh.com.sg., Koo SH; Research Laboratory, Changi General Hospital, 2 Simei Street 3, Singapore 529889, Singapore. Electronic address: seok_hwee_koo@cgh.com.sg., Ang DSW; Department of Gastroenterology and Hepatology, Changi General Hospital, 2 Simei Street 3, Singapore 529889, Singapore. Electronic address: daphne.ang.s.w@singhealth.com.sg., Ang TL; Department of Gastroenterology and Hepatology, Changi General Hospital, 2 Simei Street 3, Singapore 529889, Singapore. Electronic address: ang.tiing.leong@singhealth.com.sg., Lee HZ; Department of Laboratory Medicine, Changi General Hospital, 2 Simei Street 3, Singapore 529889, Singapore. Electronic address: Hui_Zi_Lee@cgh.com.sg., Tan TY; Department of Laboratory Medicine, Changi General Hospital, 2 Simei Street 3, Singapore 529889, Singapore. Electronic address: tan.thean.yen@singhealth.com.sg. |
| Source: | Diagnostic microbiology and infectious disease [Diagn Microbiol Infect Dis] 2026 Feb; Vol. 114 (2), pp. 117131. Date of Electronic Publication: 2025 Sep 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Biomedical Country of Publication: United States NLM ID: 8305899 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0070 (Electronic) Linking ISSN: 07328893 NLM ISO Abbreviation: Diagn Microbiol Infect Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1879-0070 |
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| DOI: | 10.1016/j.diagmicrobio.2025.117131 |