Evaluation of in vitro and in vivo release of recombinant human nerve growth factor from bioengineered human stromal lenticule.

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Title: Evaluation of in vitro and in vivo release of recombinant human nerve growth factor from bioengineered human stromal lenticule.
Authors: Lin MT; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore., Liu YC; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.; Department of Cornea and External Eye Disease, Singapore National Eye Centre, Singapore, Singapore., Lee IXY; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore., Mandatori D; Department of Medical, Oral and Biotechnological Sciences, Center for Advanced Studies and Technology (De Castro et al.), StemTeCh Group, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy., Detta N; Dompé farmaceutici SpA, Via Tommaso de Amicis, Naples, Italy., Han JYE; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore., Pelusi L; Department of Medicine and Aging Science, 'G. d'Annunzio' of Chieti-Pescara, Chieti, Italy., Mastropasqua L; Ophthalmology Clinic, Department of Medicine and Aging Science, 'G. d'Annunzio' of Chieti-Pescara, Chieti, Italy., Nubile M; Ophthalmology Clinic, Department of Medicine and Aging Science, 'G. d'Annunzio' of Chieti-Pescara, Chieti, Italy., Cattani F; Dompé farmaceutici SpA, Via Campo di Pile, L'Aquila, Italy., Romeo T; Dompé farmaceutici SpA, Via Campo di Pile, L'Aquila, Italy., Allegretti M; Dompé farmaceutici SpA, Via Campo di Pile, L'Aquila, Italy., Pandolfi A; Department of Medical, Oral and Biotechnological Sciences, Center for Advanced Studies and Technology (De Castro et al.), StemTeCh Group, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy., Dua HS; Department of Cornea and External Disease, Nottingham Hospital, Nottingham, United Kingdom., Mehta JS; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.; Department of Cornea and External Eye Disease, Singapore National Eye Centre, Singapore, Singapore.
Source: Frontiers in bioengineering and biotechnology [Front Bioeng Biotechnol] 2025 Sep 19; Vol. 13, pp. 1588629. Date of Electronic Publication: 2025 Sep 19 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101632513 Publication Model: eCollection Cited Medium: Print ISSN: 2296-4185 (Print) Linking ISSN: 22964185 NLM ISO Abbreviation: Front Bioeng Biotechnol Subsets: PubMed not MEDLINE
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  Data: Evaluation of in vitro and in vivo release of recombinant human nerve growth factor from bioengineered human stromal lenticule.
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  Data: <searchLink fieldCode="AU" term="%22Lin+MT%22">Lin MT</searchLink>; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Liu+YC%22">Liu YC</searchLink>; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.; Department of Cornea and External Eye Disease, Singapore National Eye Centre, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Lee+IXY%22">Lee IXY</searchLink>; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Mandatori+D%22">Mandatori D</searchLink>; Department of Medical, Oral and Biotechnological Sciences, Center for Advanced Studies and Technology (De Castro et al.), StemTeCh Group, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Detta+N%22">Detta N</searchLink>; Dompé farmaceutici SpA, Via Tommaso de Amicis, Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Han+JYE%22">Han JYE</searchLink>; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Pelusi+L%22">Pelusi L</searchLink>; Department of Medicine and Aging Science, 'G. d'Annunzio' of Chieti-Pescara, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Mastropasqua+L%22">Mastropasqua L</searchLink>; Ophthalmology Clinic, Department of Medicine and Aging Science, 'G. d'Annunzio' of Chieti-Pescara, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Nubile+M%22">Nubile M</searchLink>; Ophthalmology Clinic, Department of Medicine and Aging Science, 'G. d'Annunzio' of Chieti-Pescara, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Cattani+F%22">Cattani F</searchLink>; Dompé farmaceutici SpA, Via Campo di Pile, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Romeo+T%22">Romeo T</searchLink>; Dompé farmaceutici SpA, Via Campo di Pile, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Allegretti+M%22">Allegretti M</searchLink>; Dompé farmaceutici SpA, Via Campo di Pile, L'Aquila, Italy.<br /><searchLink fieldCode="AU" term="%22Pandolfi+A%22">Pandolfi A</searchLink>; Department of Medical, Oral and Biotechnological Sciences, Center for Advanced Studies and Technology (De Castro et al.), StemTeCh Group, 'G. d'Annunzio' University of Chieti-Pescara, Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Dua+HS%22">Dua HS</searchLink>; Department of Cornea and External Disease, Nottingham Hospital, Nottingham, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mehta+JS%22">Mehta JS</searchLink>; Tissue Engineering and Cell Therapy Group, Singapore Eye Research Institute, Singapore, Singapore.; Department of Cornea and External Eye Disease, Singapore National Eye Centre, Singapore, Singapore.
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        Value: 10.3389/fbioe.2025.1588629
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              Text: 2025 Sep 19
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