CAR HEMATOTOX independently predicts outcomes after CD19 CAR-T therapy for acute lymphoblastic leukemia.
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| Title: | CAR HEMATOTOX independently predicts outcomes after CD19 CAR-T therapy for acute lymphoblastic leukemia. |
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| Authors: | Valtis YK; Cell Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Lin C; Division of Hematologic Malignancies and Cellular Therapy, Duke University School of Medicine, Durham, NC., Nemirovsky D; Biostatistics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Devlin S; Biostatistics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Rejeski K; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY., Curran KJ; Cell Therapy and Cell Engineering Facility, Center for Cell Engineering, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY., Wang X; Cell Therapy and Cell Engineering Facility, Center for Cell Engineering, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY., Shah NN; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD., Jeyakumar N; Division of Hematology/Oncology, Stanford University School of Medicine, Palo Alto, CA., Miller K; Quantitative Sciences Unit, Biomedical Informatics Research (BMIR) Division, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA., Zhang A; Quantitative Sciences Unit, Biomedical Informatics Research (BMIR) Division, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA., Kota VK; Division of Hematology and Medical Oncology, Georgia Cancer Center at Augusta University, Augusta, GA., Al Darobi AH; Section of Hematology, Department of Medicine, Banner MD Anderson Cancer Center, Gilbert, AZ., Muhsen I; Section of Hematology and Oncology, Department of Medicine, Baylor College of Medicine, Houston, TX., Sasine J; Division of Hematology and Cellular Therapy, Department of Medicine, Samuel Oschin Cancer Center, Cedars-Sinai Medical Center, Los Angeles, CA., Aldoss I; Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA., Advani AS; Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH., Reshef R; Blood and Marrow Transplantation and Cell Therapy Program, Department of Medicine, Columbia University Irving Medical Center, New York, NY., Chen EC; Adult Leukemia Program, Dana-Farber Cancer Institute, Boston, MA., Kopmar N; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.; Department of Medicine, University of Washington School of Medicine, Seattle, WA., Tsai SB; Division of Hematology/Oncology, Cardinal Bernardin Cancer Center, Loyola University Medical Center, Maywood, IL., Hilal T; Department of Hematology and Oncology, Mayo Clinic, Phoenix, AZ., Shah BD; Moffitt Cancer Center and Research Institute, Tampa, FL., Faramand R; Moffitt Cancer Center and Research Institute, Tampa, FL., Solh MM; Northside Hospital Cancer Institute, Atlanta, GA., Tan V; Division of Hematology and Medical Oncology, Department of Medicine, Oregon Health and Science University, Portland, OR., Bezerra E; Division of Hematology, Ohio State University Comprehensive Cancer Center, Columbus, OH., Battiwalla M; Sarah Cannon Transplant and Cellular Therapy Program at TriStar Centennial Medical Center, Division of Hematology and Oncology, Department of Internal Medicine, HCA Healthcare, Nashville, TN., Ramakrishnan A; Sarah Cannon Transplant and Cellular Therapy Program at St. David's South Austin Medical Center, Division of Hematology/Oncology, Department of Internal Medicine, HCA Healthcare, Austin, TX., Mathews J; Sarah Cannon Transplant and Cellular Therapy Program at Texas Oncology, Division of Hematology and Oncology, Department of Internal Medicine, HCA Healthcare, Dallas, TX., Shaughnessy P; Sarah Cannon Transplant and Cellular Therapy Program at Methodist Hospital, Division of Hematology and Oncology, Department of Internal Medicine, HCA Healthcare, San Antonio, TX., Mountjoy L; Sarah Cannon Transplant and Cellular Therapy Program at Colorado Blood Cancer Institute, Division of Hematology and Oncology, Department of Internal Medicine, HCA Healthcare, Denver, CO., Hoeg RT; Division of Cellular Therapy, Bone Marrow Transplantation and Malignant Hematology, Department of Internal Medicine, University of California Davis, Sacramento, CA., Dykes KC; Division of Hematology and Medical Oncology, University of California San Diego, La Jolla, CA., Logan AC; Division of Hematology and Oncology, Department of Medicine, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA., Kumaran MV; Stem Cell Transplantation and Cellular Therapy Program, Division of Hematology and Oncology, Department of Medicine, University of Arkansas Medical Center, Little Rock, AR., Schwartz M; Division of Hematology, Department of Medicine, University of Colorado, Aurora, CO., Tracy S; Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN., Moore J; Division of Hematology and Oncology, Department of Internal Medicine, Wilmot Cancer Institute of University of Rochester, Rochester, NY., Odstrcil Bobillo S; Division of Hematology and Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT., Frey NV; Division of Hematology and Oncology, Abramson Cancer Center, Hospital of the University of Pennsylvania, Philadelphia, PA., Connor M; Division of Hematology and Oncology, Abramson Cancer Center, Hospital of the University of Pennsylvania, Philadelphia, PA., Ladha A; Department of Hematology, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA., Dholaria B; Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, TN., Sutherland K; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Palo Alto, CA., Roloff GW; Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL., Muffly LS; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Palo Alto, CA., Park JH; Cell Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY. |
| Source: | Blood advances [Blood Adv] 2026 Jan 13; Vol. 10 (1), pp. 276-288. |
| Publication Type: | Clinical Trial, Phase I; Journal Article; Multicenter Study |
| Journal Info: | Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41052404 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: CAR HEMATOTOX independently predicts outcomes after CD19 CAR-T therapy for acute lymphoblastic leukemia. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Valtis+YK%22">Valtis YK</searchLink>; Cell Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Lin+C%22">Lin C</searchLink>; Division of Hematologic Malignancies and Cellular Therapy, Duke University School of Medicine, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Nemirovsky+D%22">Nemirovsky D</searchLink>; Biostatistics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Devlin+S%22">Devlin S</searchLink>; Biostatistics Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Rejeski+K%22">Rejeski K</searchLink>; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Curran+KJ%22">Curran KJ</searchLink>; Cell Therapy and Cell Engineering Facility, Center for Cell Engineering, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Cell Therapy and Cell Engineering Facility, Center for Cell Engineering, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Shah+NN%22">Shah NN</searchLink>; Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Jeyakumar+N%22">Jeyakumar N</searchLink>; Division of Hematology/Oncology, Stanford University School of Medicine, Palo Alto, CA.<br /><searchLink fieldCode="AU" term="%22Miller+K%22">Miller K</searchLink>; Quantitative Sciences Unit, Biomedical Informatics Research (BMIR) Division, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA.<br /><searchLink fieldCode="AU" term="%22Zhang+A%22">Zhang A</searchLink>; Quantitative Sciences Unit, Biomedical Informatics Research (BMIR) Division, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA.<br /><searchLink fieldCode="AU" term="%22Kota+VK%22">Kota VK</searchLink>; Division of Hematology and Medical Oncology, Georgia Cancer Center at Augusta University, Augusta, GA.<br /><searchLink fieldCode="AU" term="%22Al+Darobi+AH%22">Al Darobi AH</searchLink>; Section of Hematology, Department of Medicine, Banner MD Anderson Cancer Center, Gilbert, AZ.<br /><searchLink fieldCode="AU" term="%22Muhsen+I%22">Muhsen I</searchLink>; Section of Hematology and Oncology, Department of Medicine, Baylor College of Medicine, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Sasine+J%22">Sasine J</searchLink>; Division of Hematology and Cellular Therapy, Department of Medicine, Samuel Oschin Cancer Center, Cedars-Sinai Medical Center, Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Aldoss+I%22">Aldoss I</searchLink>; Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Advani+AS%22">Advani AS</searchLink>; Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH.<br /><searchLink fieldCode="AU" term="%22Reshef+R%22">Reshef R</searchLink>; Blood and Marrow Transplantation and Cell Therapy Program, Department of Medicine, Columbia University Irving Medical Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Chen+EC%22">Chen EC</searchLink>; Adult Leukemia Program, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Kopmar+N%22">Kopmar N</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.; Department of Medicine, University of Washington School of Medicine, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Tsai+SB%22">Tsai SB</searchLink>; Division of Hematology/Oncology, Cardinal Bernardin Cancer Center, Loyola University Medical Center, Maywood, IL.<br /><searchLink fieldCode="AU" term="%22Hilal+T%22">Hilal T</searchLink>; Department of Hematology and Oncology, Mayo Clinic, Phoenix, AZ.<br /><searchLink fieldCode="AU" term="%22Shah+BD%22">Shah BD</searchLink>; Moffitt Cancer Center and Research Institute, Tampa, FL.<br /><searchLink fieldCode="AU" term="%22Faramand+R%22">Faramand R</searchLink>; Moffitt Cancer Center and Research Institute, Tampa, FL.<br /><searchLink fieldCode="AU" term="%22Solh+MM%22">Solh MM</searchLink>; Northside Hospital Cancer Institute, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Tan+V%22">Tan V</searchLink>; Division of Hematology and Medical Oncology, Department of Medicine, Oregon Health and Science University, Portland, OR.<br /><searchLink fieldCode="AU" term="%22Bezerra+E%22">Bezerra E</searchLink>; Division of Hematology, Ohio State University Comprehensive Cancer Center, Columbus, OH.<br /><searchLink fieldCode="AU" term="%22Battiwalla+M%22">Battiwalla M</searchLink>; Sarah Cannon Transplant and Cellular Therapy Program at TriStar Centennial Medical Center, Division of Hematology and Oncology, Department of Internal Medicine, HCA Healthcare, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Ramakrishnan+A%22">Ramakrishnan A</searchLink>; Sarah Cannon Transplant and Cellular Therapy Program at St. David's South Austin Medical Center, Division of Hematology/Oncology, Department of Internal Medicine, HCA Healthcare, Austin, TX.<br /><searchLink fieldCode="AU" term="%22Mathews+J%22">Mathews J</searchLink>; Sarah Cannon Transplant and Cellular Therapy Program at Texas Oncology, Division of Hematology and Oncology, Department of Internal Medicine, HCA Healthcare, Dallas, TX.<br /><searchLink fieldCode="AU" term="%22Shaughnessy+P%22">Shaughnessy P</searchLink>; Sarah Cannon Transplant and Cellular Therapy Program at Methodist Hospital, Division of Hematology and Oncology, Department of Internal Medicine, HCA Healthcare, San Antonio, TX.<br /><searchLink fieldCode="AU" term="%22Mountjoy+L%22">Mountjoy L</searchLink>; Sarah Cannon Transplant and Cellular Therapy Program at Colorado Blood Cancer Institute, Division of Hematology and Oncology, Department of Internal Medicine, HCA Healthcare, Denver, CO.<br /><searchLink fieldCode="AU" term="%22Hoeg+RT%22">Hoeg RT</searchLink>; Division of Cellular Therapy, Bone Marrow Transplantation and Malignant Hematology, Department of Internal Medicine, University of California Davis, Sacramento, CA.<br /><searchLink fieldCode="AU" term="%22Dykes+KC%22">Dykes KC</searchLink>; Division of Hematology and Medical Oncology, University of California San Diego, La Jolla, CA.<br /><searchLink fieldCode="AU" term="%22Logan+AC%22">Logan AC</searchLink>; Division of Hematology and Oncology, Department of Medicine, Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Kumaran+MV%22">Kumaran MV</searchLink>; Stem Cell Transplantation and Cellular Therapy Program, Division of Hematology and Oncology, Department of Medicine, University of Arkansas Medical Center, Little Rock, AR.<br /><searchLink fieldCode="AU" term="%22Schwartz+M%22">Schwartz M</searchLink>; Division of Hematology, Department of Medicine, University of Colorado, Aurora, CO.<br /><searchLink fieldCode="AU" term="%22Tracy+S%22">Tracy S</searchLink>; Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN.<br /><searchLink fieldCode="AU" term="%22Moore+J%22">Moore J</searchLink>; Division of Hematology and Oncology, Department of Internal Medicine, Wilmot Cancer Institute of University of Rochester, Rochester, NY.<br /><searchLink fieldCode="AU" term="%22Odstrcil+Bobillo+S%22">Odstrcil Bobillo S</searchLink>; Division of Hematology and Oncology, Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Frey+NV%22">Frey NV</searchLink>; Division of Hematology and Oncology, Abramson Cancer Center, Hospital of the University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Connor+M%22">Connor M</searchLink>; Division of Hematology and Oncology, Abramson Cancer Center, Hospital of the University of Pennsylvania, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Ladha+A%22">Ladha A</searchLink>; Department of Hematology, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Dholaria+B%22">Dholaria B</searchLink>; Division of Hematology and Oncology, Vanderbilt University Medical Center, Nashville, TN.<br /><searchLink fieldCode="AU" term="%22Sutherland+K%22">Sutherland K</searchLink>; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Palo Alto, CA.<br /><searchLink fieldCode="AU" term="%22Roloff+GW%22">Roloff GW</searchLink>; Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Muffly+LS%22">Muffly LS</searchLink>; Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Palo Alto, CA.<br /><searchLink fieldCode="AU" term="%22Park+JH%22">Park JH</searchLink>; Cell Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101698425%22">Blood advances</searchLink> [Blood Adv] 2026 Jan 13; Vol. 10 (1), pp. 276-288. – Name: TypePub Label: Publication Type Group: TypPub Data: Clinical Trial, Phase I; Journal Article; Multicenter Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+of+Hematology%22">American Society of Hematology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101698425 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2473-9537 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224739529%22">24739529 </searchLink><i>NLM ISO Abbreviation: </i>Blood Adv <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41052404 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1182/bloodadvances.2025017526 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 276 Titles: – TitleFull: CAR HEMATOTOX independently predicts outcomes after CD19 CAR-T therapy for acute lymphoblastic leukemia. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Valtis YK – PersonEntity: Name: NameFull: Lin C – PersonEntity: Name: NameFull: Nemirovsky D – PersonEntity: Name: NameFull: Devlin S – PersonEntity: Name: NameFull: Rejeski K – PersonEntity: Name: NameFull: Curran KJ – PersonEntity: Name: NameFull: Wang X – PersonEntity: Name: NameFull: Shah NN – PersonEntity: Name: NameFull: Jeyakumar N – PersonEntity: Name: NameFull: Miller K – PersonEntity: Name: NameFull: Zhang A – PersonEntity: Name: NameFull: Kota VK – PersonEntity: Name: NameFull: Al Darobi AH – PersonEntity: Name: NameFull: Muhsen I – PersonEntity: Name: NameFull: Sasine J – PersonEntity: Name: NameFull: Aldoss I – PersonEntity: Name: NameFull: Advani AS – PersonEntity: Name: NameFull: Reshef R – PersonEntity: Name: NameFull: Chen EC – PersonEntity: Name: NameFull: Kopmar N – PersonEntity: Name: NameFull: Tsai SB – PersonEntity: Name: NameFull: Hilal T – PersonEntity: Name: NameFull: Shah BD – PersonEntity: Name: NameFull: Faramand R – PersonEntity: Name: NameFull: Solh MM – PersonEntity: Name: NameFull: Tan V – PersonEntity: Name: NameFull: Bezerra E – PersonEntity: Name: NameFull: Battiwalla M – PersonEntity: Name: NameFull: Ramakrishnan A – PersonEntity: Name: NameFull: Mathews J – PersonEntity: Name: NameFull: Shaughnessy P – PersonEntity: Name: NameFull: Mountjoy L – PersonEntity: Name: NameFull: Hoeg RT – PersonEntity: Name: NameFull: Dykes KC – PersonEntity: Name: NameFull: Logan AC – PersonEntity: Name: NameFull: Kumaran MV – PersonEntity: Name: NameFull: Schwartz M – PersonEntity: Name: NameFull: Tracy S – PersonEntity: Name: NameFull: Moore J – PersonEntity: Name: NameFull: Odstrcil Bobillo S – PersonEntity: Name: NameFull: Frey NV – PersonEntity: Name: NameFull: Connor M – PersonEntity: Name: NameFull: Ladha A – PersonEntity: Name: NameFull: Dholaria B – PersonEntity: Name: NameFull: Sutherland K – PersonEntity: Name: NameFull: Roloff GW – PersonEntity: Name: NameFull: Muffly LS – PersonEntity: Name: NameFull: Park JH IsPartOfRelationships: – BibEntity: Dates: – D: 13 M: 01 Text: 2026 Jan 13 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2473-9537 Numbering: – Type: volume Value: 10 – Type: issue Value: 1 Titles: – TitleFull: Blood advances Type: main |
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