TGR5 dysfunction underlies chronic social defeat stress via cAMP/PKA signaling pathway in the hippocampus.
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| Title: | TGR5 dysfunction underlies chronic social defeat stress via cAMP/PKA signaling pathway in the hippocampus. |
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| Authors: | Chen X; National Health Commission Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Guangyang Bay Laboratory, Chongqing Institute for Brain and Intelligence, Chongqing, China., Zhou Q; National Health Commission Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Department of Neurology, Chongqing University Three Gorges Hospital, Chongqing, China., He Y; National Health Commission Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Guangyang Bay Laboratory, Chongqing Institute for Brain and Intelligence, Chongqing, China., Wang Y; National Health Commission Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Guangyang Bay Laboratory, Chongqing Institute for Brain and Intelligence, Chongqing, China., Jiang Y; National Health Commission Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Guangyang Bay Laboratory, Chongqing Institute for Brain and Intelligence, Chongqing, China., Ren Y; National Health Commission Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Guangyang Bay Laboratory, Chongqing Institute for Brain and Intelligence, Chongqing, China., Ren Y; National Health Commission Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Guangyang Bay Laboratory, Chongqing Institute for Brain and Intelligence, Chongqing, China., Cai J; National Health Commission Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Guangyang Bay Laboratory, Chongqing Institute for Brain and Intelligence, Chongqing, China., Yu H; National Health Commission Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Guangyang Bay Laboratory, Chongqing Institute for Brain and Intelligence, Chongqing, China., Chen C; National Health Commission Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Guangyang Bay Laboratory, Chongqing Institute for Brain and Intelligence, Chongqing, China., Cheng K; National Health Commission Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.; Department of Neurology, Yongchuan Hospital of Chongqing Medical University, Chongqing, China., Xie P; National Health Commission Key Laboratory of Diagnosis and Treatment on Brain Functional Diseases, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. xiepeng@cqmu.edu.cn.; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. xiepeng@cqmu.edu.cn.; Guangyang Bay Laboratory, Chongqing Institute for Brain and Intelligence, Chongqing, China. xiepeng@cqmu.edu.cn. |
| Source: | Translational psychiatry [Transl Psychiatry] 2025 Oct 06; Vol. 15 (1), pp. 366. Date of Electronic Publication: 2025 Oct 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2158-3188 |
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| DOI: | 10.1038/s41398-025-03599-7 |
