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IKS04, a CanAg-Targeting Antibody-Drug Conjugate with Pyrrolobenzodiazepine, Shows Enhanced Efficacy with Unconjugated Antibody Coadministration in Animal Models.

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Title: IKS04, a CanAg-Targeting Antibody-Drug Conjugate with Pyrrolobenzodiazepine, Shows Enhanced Efficacy with Unconjugated Antibody Coadministration in Animal Models.
Authors: Huang H; Chemical Engineering, University of Michigan, Ann Arbor, Michigan., Deckert J; Iksuda Therapeutics, Newcastle upon Tyne, England., Mysliwy J; Iksuda Therapeutics, Newcastle upon Tyne, England., Lodge A; Iksuda Therapeutics, Newcastle upon Tyne, England., Lutz RJ; Iksuda Therapeutics, Newcastle upon Tyne, England., Thurber GM; Chemical Engineering, University of Michigan, Ann Arbor, Michigan.; Biomedical Engineering, University of Michigan, Ann Arbor, Michigan.
Source: Molecular cancer therapeutics [Mol Cancer Ther] 2025 Dec 02; Vol. 24 (12), pp. 1845-1855.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: IKS04, a CanAg-Targeting Antibody-Drug Conjugate with Pyrrolobenzodiazepine, Shows Enhanced Efficacy with Unconjugated Antibody Coadministration in Animal Models.
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  Data: <searchLink fieldCode="AU" term="%22Huang+H%22">Huang H</searchLink>; Chemical Engineering, University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Deckert+J%22">Deckert J</searchLink>; Iksuda Therapeutics, Newcastle upon Tyne, England.<br /><searchLink fieldCode="AU" term="%22Mysliwy+J%22">Mysliwy J</searchLink>; Iksuda Therapeutics, Newcastle upon Tyne, England.<br /><searchLink fieldCode="AU" term="%22Lodge+A%22">Lodge A</searchLink>; Iksuda Therapeutics, Newcastle upon Tyne, England.<br /><searchLink fieldCode="AU" term="%22Lutz+RJ%22">Lutz RJ</searchLink>; Iksuda Therapeutics, Newcastle upon Tyne, England.<br /><searchLink fieldCode="AU" term="%22Thurber+GM%22">Thurber GM</searchLink>; Chemical Engineering, University of Michigan, Ann Arbor, Michigan.; Biomedical Engineering, University of Michigan, Ann Arbor, Michigan.
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  Data: <searchLink fieldCode="JN" term="%22101132535%22">Molecular cancer therapeutics</searchLink> [Mol Cancer Ther] 2025 Dec 02; Vol. 24 (12), pp. 1845-1855.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%2C+Inc%22">American Association for Cancer Research, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101132535 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-8514 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215357163%22">15357163 </searchLink><i>NLM ISO Abbreviation: </i>Mol Cancer Ther <i>Subsets: </i>MEDLINE
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        Value: 10.1158/1535-7163.MCT-25-0484
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      – Code: eng
        Text: English
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      – TitleFull: IKS04, a CanAg-Targeting Antibody-Drug Conjugate with Pyrrolobenzodiazepine, Shows Enhanced Efficacy with Unconjugated Antibody Coadministration in Animal Models.
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              Text: 2025 Dec 02
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            – TitleFull: Molecular cancer therapeutics
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