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Recent advances and strategies in BET bromodomain inhibition for drug discovery.

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Title: Recent advances and strategies in BET bromodomain inhibition for drug discovery.
Authors: Zhang PF; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China., Li YS; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China., Wang C; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China., Gao YH; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China., Liu JY; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China., Zhang HE; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China., Shi L; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China. Electronic address: shilei@cpu.edu.cn., Sun LP; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China. Electronic address: chslp@cpu.edu.cn.
Source: European journal of medicinal chemistry [Eur J Med Chem] 2026 Jan 05; Vol. 301, pp. 118230. Date of Electronic Publication: 2025 Oct 02.
Publication Type: Journal Article; Review
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Recent advances and strategies in BET bromodomain inhibition for drug discovery.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+PF%22">Zhang PF</searchLink>; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China.<br /><searchLink fieldCode="AU" term="%22Li+YS%22">Li YS</searchLink>; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China.<br /><searchLink fieldCode="AU" term="%22Wang+C%22">Wang C</searchLink>; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China.<br /><searchLink fieldCode="AU" term="%22Gao+YH%22">Gao YH</searchLink>; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China.<br /><searchLink fieldCode="AU" term="%22Liu+JY%22">Liu JY</searchLink>; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China.<br /><searchLink fieldCode="AU" term="%22Zhang+HE%22">Zhang HE</searchLink>; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China.<br /><searchLink fieldCode="AU" term="%22Shi+L%22">Shi L</searchLink>; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China. Electronic address: shilei@cpu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Sun+LP%22">Sun LP</searchLink>; Jiangsu Key Laboratory of Drug Design & Optimization, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, 211198, PR China. Electronic address: chslp@cpu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%220420510%22">European journal of medicinal chemistry</searchLink> [Eur J Med Chem] 2026 Jan 05; Vol. 301, pp. 118230. <i>Date of Electronic Publication: </i>2025 Oct 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editions+Scientifiques+Elsevier%22">Editions Scientifiques Elsevier </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>0420510 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1768-3254 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202235234%22">02235234 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Med Chem <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.ejmech.2025.118230
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      – Code: eng
        Text: English
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      – TitleFull: Recent advances and strategies in BET bromodomain inhibition for drug discovery.
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            NameFull: Zhang PF
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            – D: 05
              M: 01
              Text: 2026 Jan 05
              Type: published
              Y: 2026
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              Value: 301
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