The role of 5-hydroxytryptamine receptor 2A (HTR2A) gene polymorphisms in treatment-resistant obsessive-compulsive disorder: a comparative study with other treatment-resistant mental disorders.

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Title: The role of 5-hydroxytryptamine receptor 2A (HTR2A) gene polymorphisms in treatment-resistant obsessive-compulsive disorder: a comparative study with other treatment-resistant mental disorders.
Authors: Del Casale A; Department of Dynamic and Clinical Psychology and Health Studies, Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Psychiatry, Sant'Andrea University Hospital, Rome, 00189, Italy. antonio.delcasale@uniroma1.it., Gentile G; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Laboratory and Advanced Molecular Diagnostics, Sant'Andrea University Hospital, Rome, 00189, Italy., Arena JF; Department of Dynamic and Clinical Psychology and Health Studies, Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Psychiatry, Sant'Andrea University Hospital, Rome, 00189, Italy., Modesti MN; Department of Psychology, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, 00185, Italy., Zocchi C; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Psychiatry, Sant'Andrea' University Hospital, Rome, 00189, Italy., Mancino S; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Psychiatry, Sant'Andrea' University Hospital, Rome, 00189, Italy., De Luca O; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Laboratory and Advanced Molecular Diagnostics, Sant'Andrea University Hospital, Rome, 00189, Italy., Angeletti G; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Psychiatry, Sant'Andrea' University Hospital, Rome, 00189, Italy., Ferracuti S; Department of Human Neurosciences, Faculty of Medicine and Dentistry, Sapienza University of Rome, Unit of Risk Management, Sant'Andrea University Hospital, Rome, 00189, Italy., Preissner R; Structural Bioinformatics Group, Institute for Physiology, Charité-University Medicine, Berlin, 10115, Germany., Pompili M; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Psychiatry, Sant'Andrea' University Hospital, Rome, 00189, Italy., Simmaco M; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Laboratory and Advanced Molecular Diagnostics, Sant'Andrea University Hospital, Rome, 00189, Italy., Borro M; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Laboratory and Advanced Molecular Diagnostics, Sant'Andrea University Hospital, Rome, 00189, Italy.
Source: BMC psychiatry [BMC Psychiatry] 2025 Oct 07; Vol. 25 (1), pp. 938. Date of Electronic Publication: 2025 Oct 07.
Publication Type: Journal Article; Comparative Study; Observational Study
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100968559 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-244X (Electronic) Linking ISSN: 1471244X NLM ISO Abbreviation: BMC Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The role of 5-hydroxytryptamine receptor 2A (HTR2A) gene polymorphisms in treatment-resistant obsessive-compulsive disorder: a comparative study with other treatment-resistant mental disorders.
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  Data: <searchLink fieldCode="AU" term="%22Del+Casale+A%22">Del Casale A</searchLink>; Department of Dynamic and Clinical Psychology and Health Studies, Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Psychiatry, Sant'Andrea University Hospital, Rome, 00189, Italy. antonio.delcasale@uniroma1.it.<br /><searchLink fieldCode="AU" term="%22Gentile+G%22">Gentile G</searchLink>; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Laboratory and Advanced Molecular Diagnostics, Sant'Andrea University Hospital, Rome, 00189, Italy.<br /><searchLink fieldCode="AU" term="%22Arena+JF%22">Arena JF</searchLink>; Department of Dynamic and Clinical Psychology and Health Studies, Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Psychiatry, Sant'Andrea University Hospital, Rome, 00189, Italy.<br /><searchLink fieldCode="AU" term="%22Modesti+MN%22">Modesti MN</searchLink>; Department of Psychology, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, 00185, Italy.<br /><searchLink fieldCode="AU" term="%22Zocchi+C%22">Zocchi C</searchLink>; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Psychiatry, Sant'Andrea' University Hospital, Rome, 00189, Italy.<br /><searchLink fieldCode="AU" term="%22Mancino+S%22">Mancino S</searchLink>; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Psychiatry, Sant'Andrea' University Hospital, Rome, 00189, Italy.<br /><searchLink fieldCode="AU" term="%22De+Luca+O%22">De Luca O</searchLink>; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Laboratory and Advanced Molecular Diagnostics, Sant'Andrea University Hospital, Rome, 00189, Italy.<br /><searchLink fieldCode="AU" term="%22Angeletti+G%22">Angeletti G</searchLink>; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Psychiatry, Sant'Andrea' University Hospital, Rome, 00189, Italy.<br /><searchLink fieldCode="AU" term="%22Ferracuti+S%22">Ferracuti S</searchLink>; Department of Human Neurosciences, Faculty of Medicine and Dentistry, Sapienza University of Rome, Unit of Risk Management, Sant'Andrea University Hospital, Rome, 00189, Italy.<br /><searchLink fieldCode="AU" term="%22Preissner+R%22">Preissner R</searchLink>; Structural Bioinformatics Group, Institute for Physiology, Charité-University Medicine, Berlin, 10115, Germany.<br /><searchLink fieldCode="AU" term="%22Pompili+M%22">Pompili M</searchLink>; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Psychiatry, Sant'Andrea' University Hospital, Rome, 00189, Italy.<br /><searchLink fieldCode="AU" term="%22Simmaco+M%22">Simmaco M</searchLink>; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Laboratory and Advanced Molecular Diagnostics, Sant'Andrea University Hospital, Rome, 00189, Italy.<br /><searchLink fieldCode="AU" term="%22Borro+M%22">Borro M</searchLink>; Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Unit of Laboratory and Advanced Molecular Diagnostics, Sant'Andrea University Hospital, Rome, 00189, Italy.
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  Data: <searchLink fieldCode="JN" term="%22100968559%22">BMC psychiatry</searchLink> [BMC Psychiatry] 2025 Oct 07; Vol. 25 (1), pp. 938. <i>Date of Electronic Publication: </i>2025 Oct 07.
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