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Polatuzumab vedotin in CNS lymphoma: proof-of-concept study for blood-brain barrier penetration.

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Title: Polatuzumab vedotin in CNS lymphoma: proof-of-concept study for blood-brain barrier penetration.
Authors: Gao L; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA., Kallam A; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA., Shouse G; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA., Baird JH; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA., Pak S; Department of Pharmacy, City of Hope, Duarte, CA., Qin Y; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA., Song JY; Department of Pathology, City of Hope, Duarte, CA., Marcucci G; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Department of Hematological Malignancies and Translational Science, Beckman Research Institute, City of Hope, Duarte, CA.; Hematopoietic Tissue Biorepository, Shared Resource Core Facility, City of Hope, Duarte, CA., Ghoda LY; Department of Hematological Malignancies and Translational Science, Beckman Research Institute, City of Hope, Duarte, CA.; Hematopoietic Tissue Biorepository, Shared Resource Core Facility, City of Hope, Duarte, CA., Guillen C; Hematopoietic Tissue Biorepository, Shared Resource Core Facility, City of Hope, Duarte, CA., Hyung SJ; Genentech Inc, South San Francisco, CA., Saad OM; Genentech Inc, South San Francisco, CA., Davis H; Genentech Inc, South San Francisco, CA., Dere R; Genentech Inc, South San Francisco, CA., Batlevi CL; Genentech Inc, South San Francisco, CA., Meinert J; Genentech Inc, South San Francisco, CA., Budde LE; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA., Danilov AV; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA., Herrera AF; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA., Kwak LW; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA., Forman SJ; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA., Godfrey JK; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA.
Source: Blood advances [Blood Adv] 2025 Dec 23; Vol. 9 (24), pp. 6425-6431.
Publication Type: Journal Article
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
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  Data: Polatuzumab vedotin in CNS lymphoma: proof-of-concept study for blood-brain barrier penetration.
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  Data: <searchLink fieldCode="AU" term="%22Gao+L%22">Gao L</searchLink>; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Kallam+A%22">Kallam A</searchLink>; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Shouse+G%22">Shouse G</searchLink>; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Baird+JH%22">Baird JH</searchLink>; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Pak+S%22">Pak S</searchLink>; Department of Pharmacy, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Qin+Y%22">Qin Y</searchLink>; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Song+JY%22">Song JY</searchLink>; Department of Pathology, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Marcucci+G%22">Marcucci G</searchLink>; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Department of Hematological Malignancies and Translational Science, Beckman Research Institute, City of Hope, Duarte, CA.; Hematopoietic Tissue Biorepository, Shared Resource Core Facility, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Ghoda+LY%22">Ghoda LY</searchLink>; Department of Hematological Malignancies and Translational Science, Beckman Research Institute, City of Hope, Duarte, CA.; Hematopoietic Tissue Biorepository, Shared Resource Core Facility, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Guillen+C%22">Guillen C</searchLink>; Hematopoietic Tissue Biorepository, Shared Resource Core Facility, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Hyung+SJ%22">Hyung SJ</searchLink>; Genentech Inc, South San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Saad+OM%22">Saad OM</searchLink>; Genentech Inc, South San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Davis+H%22">Davis H</searchLink>; Genentech Inc, South San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Dere+R%22">Dere R</searchLink>; Genentech Inc, South San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Batlevi+CL%22">Batlevi CL</searchLink>; Genentech Inc, South San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Meinert+J%22">Meinert J</searchLink>; Genentech Inc, South San Francisco, CA.<br /><searchLink fieldCode="AU" term="%22Budde+LE%22">Budde LE</searchLink>; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Danilov+AV%22">Danilov AV</searchLink>; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Herrera+AF%22">Herrera AF</searchLink>; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Kwak+LW%22">Kwak LW</searchLink>; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Forman+SJ%22">Forman SJ</searchLink>; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA.<br /><searchLink fieldCode="AU" term="%22Godfrey+JK%22">Godfrey JK</searchLink>; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.; Toni Stephenson Lymphoma Center, City of Hope, Duarte, CA.
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              Text: 2025 Dec 23
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