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Flow-Sensitive HEG1 Controls eNOS Activity to Prevent Endothelial Dysfunction, Hypertension, and Atherosclerosis.

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Title: Flow-Sensitive HEG1 Controls eNOS Activity to Prevent Endothelial Dysfunction, Hypertension, and Atherosclerosis.
Authors: Clark MD; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.).; Division of Cardiology, Department of Medicine (M.D.C., J.A.B.-K., H.J.), Emory University, Atlanta, GA., Kim Y; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.)., Romero CA; Division of Nephrology, Department of Medicine (C.A.R.), Emory University, Atlanta, GA., Kang DW; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.)., Baek KI; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.)., Song EJ; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.)., Kellum CE; Division of Nephrology, Department of Medicine, The University of Alabama at Birmingham (C.E.K., J.S.P.)., Bowman-Kirigin JA; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.).; Division of Cardiology, Department of Medicine (M.D.C., J.A.B.-K., H.J.), Emory University, Atlanta, GA., Park C; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.)., Hung RC; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.)., Choi L; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.)., Kapoor V; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.)., Tsuji S; Department of Medical Technology and Clinical Engineering, Gunma University of Health and Welfare, Maebashi, Japan (S.T.)., Pollock JS; Division of Nephrology, Department of Medicine, The University of Alabama at Birmingham (C.E.K., J.S.P.)., Jo H; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.).; Division of Cardiology, Department of Medicine (M.D.C., J.A.B.-K., H.J.), Emory University, Atlanta, GA.
Source: Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2025 Dec; Vol. 45 (12), pp. 2292-2295. Date of Electronic Publication: 2025 Oct 09.
Publication Type: Letter
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9505803 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4636 (Electronic) Linking ISSN: 10795642 NLM ISO Abbreviation: Arterioscler Thromb Vasc Biol Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: Flow-Sensitive HEG1 Controls eNOS Activity to Prevent Endothelial Dysfunction, Hypertension, and Atherosclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Clark+MD%22">Clark MD</searchLink>; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.).; Division of Cardiology, Department of Medicine (M.D.C., J.A.B.-K., H.J.), Emory University, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Kim+Y%22">Kim Y</searchLink>; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.).<br /><searchLink fieldCode="AU" term="%22Romero+CA%22">Romero CA</searchLink>; Division of Nephrology, Department of Medicine (C.A.R.), Emory University, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Kang+DW%22">Kang DW</searchLink>; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.).<br /><searchLink fieldCode="AU" term="%22Baek+KI%22">Baek KI</searchLink>; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.).<br /><searchLink fieldCode="AU" term="%22Song+EJ%22">Song EJ</searchLink>; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.).<br /><searchLink fieldCode="AU" term="%22Kellum+CE%22">Kellum CE</searchLink>; Division of Nephrology, Department of Medicine, The University of Alabama at Birmingham (C.E.K., J.S.P.).<br /><searchLink fieldCode="AU" term="%22Bowman-Kirigin+JA%22">Bowman-Kirigin JA</searchLink>; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.).; Division of Cardiology, Department of Medicine (M.D.C., J.A.B.-K., H.J.), Emory University, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Park+C%22">Park C</searchLink>; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.).<br /><searchLink fieldCode="AU" term="%22Hung+RC%22">Hung RC</searchLink>; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.).<br /><searchLink fieldCode="AU" term="%22Choi+L%22">Choi L</searchLink>; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.).<br /><searchLink fieldCode="AU" term="%22Kapoor+V%22">Kapoor V</searchLink>; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.).<br /><searchLink fieldCode="AU" term="%22Tsuji+S%22">Tsuji S</searchLink>; Department of Medical Technology and Clinical Engineering, Gunma University of Health and Welfare, Maebashi, Japan (S.T.).<br /><searchLink fieldCode="AU" term="%22Pollock+JS%22">Pollock JS</searchLink>; Division of Nephrology, Department of Medicine, The University of Alabama at Birmingham (C.E.K., J.S.P.).<br /><searchLink fieldCode="AU" term="%22Jo+H%22">Jo H</searchLink>; Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta (M.D.C., Y.K., D.W.K., K.I.B., E.J.S., J.A.B.-K., C.P., R.-C.H., L.C., V.K., H.J.).; Division of Cardiology, Department of Medicine (M.D.C., J.A.B.-K., H.J.), Emory University, Atlanta, GA.
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  Data: <searchLink fieldCode="JN" term="%229505803%22">Arteriosclerosis, thrombosis, and vascular biology</searchLink> [Arterioscler Thromb Vasc Biol] 2025 Dec; Vol. 45 (12), pp. 2292-2295. <i>Date of Electronic Publication: </i>2025 Oct 09.
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        Value: 10.1161/ATVBAHA.125.323285
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              Text: 2025 Dec
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