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Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2.

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Title: Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2.
Authors: Changrob S; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA., Yasuhara A; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA., Park S; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Bangaru S; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Li L; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA., Troxell CA; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA., Halfmann PJ; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison , Madison, WI, USA., Erickson SA; University of Chicago Department of Medicine, Section of Rheumatology , Chicago, IL, USA., Catanzaro NJ; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Yuan M; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Zhou P; Department of Immunology and Microbiology, IAVI Neutralizing Antibody Center and Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Huang M; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA., Wilbanks GD; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA., McGrath JJC; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA., Singh G; Center for Vaccine Research and Pandemic Preparedness, Department of Microbiology, Icahn School of Medicine at Mount Sinai , New York, NY, USA., Nelson SA; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA., Fu Y; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA., Zheng NY; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA., Carayannopoulos SM; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA., Dugan HL; University of Chicago Department of Medicine, Section of Rheumatology , Chicago, IL, USA., Shaw DG; University of Chicago Department of Medicine, Section of Rheumatology , Chicago, IL, USA., Stamper CT; University of Chicago Department of Medicine, Section of Rheumatology , Chicago, IL, USA., Madariaga MLL; Department of Surgery, University of Chicago, Chicago, IL, USA., Krammer F; Center for Vaccine Research and Pandemic Preparedness, Department of Microbiology, Icahn School of Medicine at Mount Sinai , New York, NY, USA.; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ignaz Semmelweis Institute, Interuniversity Institute for Infection Research, Medical University of Vienna , Vienna, Austria., Andrabi R; Department of Immunology and Microbiology, IAVI Neutralizing Antibody Center and Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA., Burton DR; Department of Immunology and Microbiology, IAVI Neutralizing Antibody Center and Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University , Cambridge, MA, USA., Ward AB; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA., Wilson IA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.; The Skaggs Institute for Chemical Biology, The Scripps Research Institute , La Jolla, CA, USA., Kawaoka Y; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison , Madison, WI, USA.; Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.; Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), University of Tokyo, Tokyo, Japan., Wilson PC; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA.
Source: The Journal of experimental medicine [J Exp Med] 2025 Dec 01; Vol. 222 (12). Date of Electronic Publication: 2025 Oct 09.
Publication Type: Journal Article
Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE
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  Data: Common cold embecovirus imprinting primes broadly neutralizing antibody responses to SARS-CoV-2 S2.
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  Data: <searchLink fieldCode="AU" term="%22Changrob+S%22">Changrob S</searchLink>; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Yasuhara+A%22">Yasuhara A</searchLink>; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Park+S%22">Park S</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bangaru+S%22">Bangaru S</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Troxell+CA%22">Troxell CA</searchLink>; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Halfmann+PJ%22">Halfmann PJ</searchLink>; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison , Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Erickson+SA%22">Erickson SA</searchLink>; University of Chicago Department of Medicine, Section of Rheumatology , Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Catanzaro+NJ%22">Catanzaro NJ</searchLink>; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Yuan+M%22">Yuan M</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+P%22">Zhou P</searchLink>; Department of Immunology and Microbiology, IAVI Neutralizing Antibody Center and Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Huang+M%22">Huang M</searchLink>; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wilbanks+GD%22">Wilbanks GD</searchLink>; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22McGrath+JJC%22">McGrath JJC</searchLink>; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Singh+G%22">Singh G</searchLink>; Center for Vaccine Research and Pandemic Preparedness, Department of Microbiology, Icahn School of Medicine at Mount Sinai , New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Nelson+SA%22">Nelson SA</searchLink>; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Fu+Y%22">Fu Y</searchLink>; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Zheng+NY%22">Zheng NY</searchLink>; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Carayannopoulos+SM%22">Carayannopoulos SM</searchLink>; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Dugan+HL%22">Dugan HL</searchLink>; University of Chicago Department of Medicine, Section of Rheumatology , Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Shaw+DG%22">Shaw DG</searchLink>; University of Chicago Department of Medicine, Section of Rheumatology , Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Stamper+CT%22">Stamper CT</searchLink>; University of Chicago Department of Medicine, Section of Rheumatology , Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Madariaga+MLL%22">Madariaga MLL</searchLink>; Department of Surgery, University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Krammer+F%22">Krammer F</searchLink>; Center for Vaccine Research and Pandemic Preparedness, Department of Microbiology, Icahn School of Medicine at Mount Sinai , New York, NY, USA.; Department of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Ignaz Semmelweis Institute, Interuniversity Institute for Infection Research, Medical University of Vienna , Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Andrabi+R%22">Andrabi R</searchLink>; Department of Immunology and Microbiology, IAVI Neutralizing Antibody Center and Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Burton+DR%22">Burton DR</searchLink>; Department of Immunology and Microbiology, IAVI Neutralizing Antibody Center and Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University , Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ward+AB%22">Ward AB</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+IA%22">Wilson IA</searchLink>; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.; The Skaggs Institute for Chemical Biology, The Scripps Research Institute , La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Kawaoka+Y%22">Kawaoka Y</searchLink>; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison , Madison, WI, USA.; Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.; Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), University of Tokyo, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Wilson+PC%22">Wilson PC</searchLink>; Drukier Institute for Children's Health, Weill Cornell Medicine , New York, NY, USA.
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