Association of Metformin Use With Osteoarthritis Incidence, Progression, and Joint Arthroplasty Risk in the Knee and Hip: A Systematic Review and Meta-Analysis.

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Title: Association of Metformin Use With Osteoarthritis Incidence, Progression, and Joint Arthroplasty Risk in the Knee and Hip: A Systematic Review and Meta-Analysis.
Authors: Yao K; Henan University of Chinese Medicine, Zhengzhou, China., Yue C; Evidence-based Medicine Center, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Luoyang, China., Li Y; Rehabilitation Therapy Center, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Luoyang, China., Li F; Evidence-based Medicine Center, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Luoyang, China., Wang Q; Evidence-based Medicine Center, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Luoyang, China., Guo J; Henan University of Chinese Medicine, Zhengzhou, China; Evidence-based Medicine Center, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Luoyang, China.
Source: The Journal of arthroplasty [J Arthroplasty] 2026 May; Vol. 41 (5), pp. 1562-1570.e3. Date of Electronic Publication: 2025 Oct 09.
Publication Type: Journal Article; Systematic Review; Meta-Analysis; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Taylor and Francis Country of Publication: United States NLM ID: 8703515 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8406 (Electronic) Linking ISSN: 08835403 NLM ISO Abbreviation: J Arthroplasty Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Association of Metformin Use With Osteoarthritis Incidence, Progression, and Joint Arthroplasty Risk in the Knee and Hip: A Systematic Review and Meta-Analysis.
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  Data: <searchLink fieldCode="AU" term="%22Yao+K%22">Yao K</searchLink>; Henan University of Chinese Medicine, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Yue+C%22">Yue C</searchLink>; Evidence-based Medicine Center, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Luoyang, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Rehabilitation Therapy Center, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Luoyang, China.<br /><searchLink fieldCode="AU" term="%22Li+F%22">Li F</searchLink>; Evidence-based Medicine Center, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Luoyang, China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Evidence-based Medicine Center, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Luoyang, China.<br /><searchLink fieldCode="AU" term="%22Guo+J%22">Guo J</searchLink>; Henan University of Chinese Medicine, Zhengzhou, China; Evidence-based Medicine Center, Luoyang Orthopedic Hospital of Henan Province, Orthopedic Hospital of Henan Province, Luoyang, China.
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  Data: <searchLink fieldCode="JN" term="%228703515%22">The Journal of arthroplasty</searchLink> [J Arthroplasty] 2026 May; Vol. 41 (5), pp. 1562-1570.e3. <i>Date of Electronic Publication: </i>2025 Oct 09.
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  Data: Journal Article; Systematic Review; Meta-Analysis; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+and+Francis%22">Taylor and Francis </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8703515 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-8406 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208835403%22">08835403 </searchLink><i>NLM ISO Abbreviation: </i>J Arthroplasty <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1016/j.arth.2025.09.050
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      – Code: eng
        Text: English
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      – TitleFull: Association of Metformin Use With Osteoarthritis Incidence, Progression, and Joint Arthroplasty Risk in the Knee and Hip: A Systematic Review and Meta-Analysis.
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            NameFull: Yao K
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              Text: 2026 May
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              Y: 2026
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