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Targeting the HIF1A-UCA1-PTBP3 axis: a potential therapeutic strategy for head and neck cancer.

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Title: Targeting the HIF1A-UCA1-PTBP3 axis: a potential therapeutic strategy for head and neck cancer.
Authors: Sim LC; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C., Kuo YZ; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C.; Department of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C., Cheng TC; Department of Otolaryngology, An Nan Hospital, China Medical University, Tainan, Taiwan, R.O.C., Chen CL; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C., Hsiao JR; Department of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C., Ooi MX; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C., Yun Z; Department of Biochemistry, School of Medicine, Case Western Reserve University, Cleveland, OH, U.S.A., Kao HY; Department of Biochemistry, School of Medicine, Case Western Reserve University, Cleveland, OH, U.S.A., Tsai ST; Department of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C.. T602511@mail.ncku.edu.tw.; Research Department, Changhua Christian Hospital, Changhua City, Taiwan, R.O.C.. T602511@mail.ncku.edu.tw., Wu LW; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C.. liwhawu@mail.ncku.edu.tw.; Department of Laboratory Science and Technology, College of Health Sciences,, Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C.. liwhawu@mail.ncku.edu.tw.
Source: BMC cancer [BMC Cancer] 2025 Oct 09; Vol. 25 (1), pp. 1536. Date of Electronic Publication: 2025 Oct 09.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting the HIF1A-UCA1-PTBP3 axis: a potential therapeutic strategy for head and neck cancer.
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  Data: <searchLink fieldCode="AU" term="%22Sim+LC%22">Sim LC</searchLink>; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Kuo+YZ%22">Kuo YZ</searchLink>; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C.; Department of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Cheng+TC%22">Cheng TC</searchLink>; Department of Otolaryngology, An Nan Hospital, China Medical University, Tainan, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Chen+CL%22">Chen CL</searchLink>; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Hsiao+JR%22">Hsiao JR</searchLink>; Department of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Ooi+MX%22">Ooi MX</searchLink>; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C.<br /><searchLink fieldCode="AU" term="%22Yun+Z%22">Yun Z</searchLink>; Department of Biochemistry, School of Medicine, Case Western Reserve University, Cleveland, OH, U.S.A.<br /><searchLink fieldCode="AU" term="%22Kao+HY%22">Kao HY</searchLink>; Department of Biochemistry, School of Medicine, Case Western Reserve University, Cleveland, OH, U.S.A.<br /><searchLink fieldCode="AU" term="%22Tsai+ST%22">Tsai ST</searchLink>; Department of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C.. T602511@mail.ncku.edu.tw.; Research Department, Changhua Christian Hospital, Changhua City, Taiwan, R.O.C.. T602511@mail.ncku.edu.tw.<br /><searchLink fieldCode="AU" term="%22Wu+LW%22">Wu LW</searchLink>; Institute of Molecular Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C.. liwhawu@mail.ncku.edu.tw.; Department of Laboratory Science and Technology, College of Health Sciences,, Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C.. liwhawu@mail.ncku.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%22100967800%22">BMC cancer</searchLink> [BMC Cancer] 2025 Oct 09; Vol. 25 (1), pp. 1536. <i>Date of Electronic Publication: </i>2025 Oct 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100967800 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2407 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712407%22">14712407 </searchLink><i>NLM ISO Abbreviation: </i>BMC Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12885-025-15020-z
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            – D: 09
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              Text: 2025 Oct 09
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