CardioPulmonary resuscitation with Argon (CPAr): A protocol for a randomised controlled multicentre clinical trial.

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Title: CardioPulmonary resuscitation with Argon (CPAr): A protocol for a randomised controlled multicentre clinical trial.
Authors: Ristagno G; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.; Department of Anaesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Staszewsky L; Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Merigo G; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.; Department of Anaesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Magliocca A; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy., Cucino A; Anaesthesia and Intensive Care 1, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari (APSS), Trento, Italy., Meessen J; Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Fumagalli F; Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Pozzi M; School of Medicine and Surgery, University of Milano Bicocca, Monza, Italy.; Department of Emergency and Intensive Care, Fondazione IRCSS San Gerardo dei Tintori, Monza, Italy., Galazzi A; Department of Medicine and Surgery, LUM University, Casamassima, Bari, Italy., Sandroni C; Department of Intensive Care, Emergency Medicine and Anaesthesiology, Fondazione Policlinico Universitario 'Agostino Gemelli'-IRCCS, Rome, Italy.; Institute of Anaesthesiology and Intensive Care Medicine, Università Cattolica del Sacro Cuore, Rome, Italy., Meneguzzi M; Department of Anaesthesia and Intensive Care, Pordenone Hospital, Azienda Sanitaria Friuli Occidentale, Italy., Marangone A; Department of Anaesthesia and Intensive Care, Pordenone Hospital, Azienda Sanitaria Friuli Occidentale, Italy., Robba C; IRCCS Policlinico San Martino, Genoa, Italy.; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy., Roman-Pognuz E; Department of Medical Science, University of Trieste, Trieste, Italy., Salati G; UOC Anestesia e Rianimazione, IRCCS Arcispedale Santa Maria Nuova, Reggio Emilia, Italy., Picetti E; Department of Anaesthesia and Intensive Care, Parma University Hospital, Parma, Italy., Novelli D; Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Bellani G; Anaesthesia and Intensive Care 1, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari (APSS), Trento, Italy.; Centre for Medical Sciences, University of Trento, Trento, Italy., Panigada M; Department of Anaesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Wik L; Norwegian National Advisory Unit on Prehospital Emergency Medicine, Division of Prehospital Care, Oslo University Hospital, Oslo, Norway.; Air Ambulance Department, Doctor Respond Car 119, Division of Prehospital Care, Oslo University Hospital, Oslo, Norway.; Department of Anaesthesiology, Division of Emergency Medicine, Oslo University Hospital, Oslo, Norway., Garattini S; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Foti G; School of Medicine and Surgery, University of Milano Bicocca, Monza, Italy.; Department of Emergency and Intensive Care, Fondazione IRCSS San Gerardo dei Tintori, Monza, Italy., Antonelli M; Department of Intensive Care, Emergency Medicine and Anaesthesiology, Fondazione Policlinico Universitario 'Agostino Gemelli'-IRCCS, Rome, Italy.; Institute of Anaesthesiology and Intensive Care Medicine, Università Cattolica del Sacro Cuore, Rome, Italy., Zanier E; Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy., Grasselli G; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.; Department of Anaesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Latini R; Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
Corporate Authors: CPAr Study group
Source: Resuscitation plus [Resusc Plus] 2025 Sep 10; Vol. 26, pp. 101096. Date of Electronic Publication: 2025 Sep 10 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101774410 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-5204 (Electronic) Linking ISSN: 26665204 NLM ISO Abbreviation: Resusc Plus Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: CardioPulmonary resuscitation with Argon (CPAr): A protocol for a randomised controlled multicentre clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22Ristagno+G%22">Ristagno G</searchLink>; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.; Department of Anaesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Staszewsky+L%22">Staszewsky L</searchLink>; Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Merigo+G%22">Merigo G</searchLink>; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.; Department of Anaesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Magliocca+A%22">Magliocca A</searchLink>; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cucino+A%22">Cucino A</searchLink>; Anaesthesia and Intensive Care 1, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari (APSS), Trento, Italy.<br /><searchLink fieldCode="AU" term="%22Meessen+J%22">Meessen J</searchLink>; Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Fumagalli+F%22">Fumagalli F</searchLink>; Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pozzi+M%22">Pozzi M</searchLink>; School of Medicine and Surgery, University of Milano Bicocca, Monza, Italy.; Department of Emergency and Intensive Care, Fondazione IRCSS San Gerardo dei Tintori, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Galazzi+A%22">Galazzi A</searchLink>; Department of Medicine and Surgery, LUM University, Casamassima, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Sandroni+C%22">Sandroni C</searchLink>; Department of Intensive Care, Emergency Medicine and Anaesthesiology, Fondazione Policlinico Universitario 'Agostino Gemelli'-IRCCS, Rome, Italy.; Institute of Anaesthesiology and Intensive Care Medicine, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Meneguzzi+M%22">Meneguzzi M</searchLink>; Department of Anaesthesia and Intensive Care, Pordenone Hospital, Azienda Sanitaria Friuli Occidentale, Italy.<br /><searchLink fieldCode="AU" term="%22Marangone+A%22">Marangone A</searchLink>; Department of Anaesthesia and Intensive Care, Pordenone Hospital, Azienda Sanitaria Friuli Occidentale, Italy.<br /><searchLink fieldCode="AU" term="%22Robba+C%22">Robba C</searchLink>; IRCCS Policlinico San Martino, Genoa, Italy.; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Roman-Pognuz+E%22">Roman-Pognuz E</searchLink>; Department of Medical Science, University of Trieste, Trieste, Italy.<br /><searchLink fieldCode="AU" term="%22Salati+G%22">Salati G</searchLink>; UOC Anestesia e Rianimazione, IRCCS Arcispedale Santa Maria Nuova, Reggio Emilia, Italy.<br /><searchLink fieldCode="AU" term="%22Picetti+E%22">Picetti E</searchLink>; Department of Anaesthesia and Intensive Care, Parma University Hospital, Parma, Italy.<br /><searchLink fieldCode="AU" term="%22Novelli+D%22">Novelli D</searchLink>; Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bellani+G%22">Bellani G</searchLink>; Anaesthesia and Intensive Care 1, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari (APSS), Trento, Italy.; Centre for Medical Sciences, University of Trento, Trento, Italy.<br /><searchLink fieldCode="AU" term="%22Panigada+M%22">Panigada M</searchLink>; Department of Anaesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Wik+L%22">Wik L</searchLink>; Norwegian National Advisory Unit on Prehospital Emergency Medicine, Division of Prehospital Care, Oslo University Hospital, Oslo, Norway.; Air Ambulance Department, Doctor Respond Car 119, Division of Prehospital Care, Oslo University Hospital, Oslo, Norway.; Department of Anaesthesiology, Division of Emergency Medicine, Oslo University Hospital, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Garattini+S%22">Garattini S</searchLink>; Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Foti+G%22">Foti G</searchLink>; School of Medicine and Surgery, University of Milano Bicocca, Monza, Italy.; Department of Emergency and Intensive Care, Fondazione IRCSS San Gerardo dei Tintori, Monza, Italy.<br /><searchLink fieldCode="AU" term="%22Antonelli+M%22">Antonelli M</searchLink>; Department of Intensive Care, Emergency Medicine and Anaesthesiology, Fondazione Policlinico Universitario 'Agostino Gemelli'-IRCCS, Rome, Italy.; Institute of Anaesthesiology and Intensive Care Medicine, Università Cattolica del Sacro Cuore, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Zanier+E%22">Zanier E</searchLink>; Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Grasselli+G%22">Grasselli G</searchLink>; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.; Department of Anaesthesiology, Intensive Care and Emergency, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Latini+R%22">Latini R</searchLink>; Department of Acute Brain and Cardiovascular Injury, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.
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