Machine learning risk stratification strategy for multiple myeloma: Insights from the EMN-HARMONY Alliance platform.

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Title: Machine learning risk stratification strategy for multiple myeloma: Insights from the EMN-HARMONY Alliance platform.
Authors: Mosquera Orgueira A; Department of Hematology, IDIS University Hospital of Santiago de Compostela Santiago de Compostela Spain., Gonzalez Perez MS; Department of Hematology, IDIS University Hospital of Santiago de Compostela Santiago de Compostela Spain., D'Agostino M; Division of Hematology, AOU Città della Salute e della Scienza di Torino University of Torino Torino Italy.; Department of Molecular Biotechnology and Health Sciences University of Torino Torino Italy., Cairns DA; Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research University of Leeds Leeds United Kingdom., Larocca A; Department of Molecular Biotechnology and Health Sciences, Division of Hematology University of Torino Torino Italy., Palacios JJL; Hospital Universitario 12 de Octubre CIBER-ONC CB16/12/00369, CNIO Madrid Spain., Wester R; Department of Hematology Erasmus MC Cancer Institute Rotterdam The Netherlands., Bertsch U; National Center for Tumor Diseases Heidelberg Heidelberg Germany.; Department of Medicine V, Heidelberg Myeloma Center University Hospital Heidelberg Heidelberg Germany., Waage A; Institute of Clinical and Molecular Medicine Norwegian University of Science and Technology and St. Olavs Hospital Trondheim Norway., Zamagni E; Department of Medical and Surgical Sciences, 'Seràgnoli' Institute of Hematology University of Bologna Bologna Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna Bologna Italy., Pérez Míguez C; Department of Hematology, IDIS University Hospital of Santiago de Compostela Santiago de Compostela Spain., Rojas Martínez JA; Department of Hematology, IDIS University Hospital of Santiago de Compostela Santiago de Compostela Spain., Mai EK; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, University Hospital Heidelberg GMMG Study Group Heidelberg Germany., Crucitti D; Department of Hematology, IDIS University Hospital of Santiago de Compostela Santiago de Compostela Spain., Salwender H; Asklepios Tumorzentrum Hamburg Asklepios Hospital Hamburg Altona and St. Georg Hamburg Germany., Dall'Olio D; Department of Medical and Surgical Sciences (DIMEC) University of Bologna Bologna Italy., Castellani G; Department of Medical and Surgical Sciences (DIMEC) University of Bologna Bologna Italy., Piñeiro Fiel M; Department of Hematology, IDIS University Hospital of Santiago de Compostela Santiago de Compostela Spain., Bringhen S; AOU Città della Salute e della Scienza di Torino Torino Italy., Zweegman S; Department of Hematology, Amsterdam UMC, Cancer Center Amsterdam Vrije Universiteit Amsterdam Amsterdam The Netherlands., Cavo M; IRCCS Azienda Ospedaliero-Universitaria di Bologna Institute of Hematology 'L. e A. Seràgnoli' Bologna Italy.; Department of Medical and Surgical Sciences University of Bologna Bologna Italy., Iqbal S; Medical Information Scientific Engagement Johnson & Johnson Innovative Medicines New York New York United States., Hernandez Rivas JM; Department of Medicine, Cancer Research Center (IBMCC, USAL-CSIC), Institute of Biomedical Research of Salamanca (IBSAL) University of Salamanca Salamanca Spain., Bruno B; Division of Hematology, AOU Città della Salute e della Scienza di Torino University of Torino Torino Italy.; Department of Molecular Biotechnology and Health Sciences University of Torino Torino Italy., Cook G; Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research University of Leeds Leeds United Kingdom., Kaiser MF; Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research University of Leeds Leeds United Kingdom.; The Institute of Cancer Research and the Royal Marsden Hospital London United Kingdom., Goldschmidt H; National Center for Tumor Diseases Heidelberg Heidelberg Germany.; Department of Medicine V, Heidelberg Myeloma Center University Hospital Heidelberg Heidelberg Germany., Van De Donk NWCJ; Department of Hematology, Amsterdam UMC, Cancer Center Amsterdam Vrije Universiteit Amsterdam Amsterdam The Netherlands., Jackson G; Department of Haematology Newcastle University Newcastle Upon Tyne United Kingdom., San-Miguel JF; Clínica Universidad de Navarra CIMA, IDISNA, CIBERONC (CB16/12/00369) Pamplona Spain., Boccadoro M; European Myeloma Network (EMN) Italy., Mateos MV; Department of Medicine, Cancer Research Center (IBMCC, USAL-CSIC), Institute of Biomedical Research of Salamanca (IBSAL) University of Salamanca Salamanca Spain., Sonneveld P; Department of Hematology Erasmus MC Cancer Institute Rotterdam The Netherlands.
Source: HemaSphere [Hemasphere] 2025 Oct 09; Vol. 9 (10), pp. e70228. Date of Electronic Publication: 2025 Oct 09 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Mosquera+Orgueira+A%22">Mosquera Orgueira A</searchLink>; Department of Hematology, IDIS University Hospital of Santiago de Compostela Santiago de Compostela Spain.<br /><searchLink fieldCode="AU" term="%22Gonzalez+Perez+MS%22">Gonzalez Perez MS</searchLink>; Department of Hematology, IDIS University Hospital of Santiago de Compostela Santiago de Compostela Spain.<br /><searchLink fieldCode="AU" term="%22D'Agostino+M%22">D'Agostino M</searchLink>; Division of Hematology, AOU Città della Salute e della Scienza di Torino University of Torino Torino Italy.; Department of Molecular Biotechnology and Health Sciences University of Torino Torino Italy.<br /><searchLink fieldCode="AU" term="%22Cairns+DA%22">Cairns DA</searchLink>; Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research University of Leeds Leeds United Kingdom.<br /><searchLink fieldCode="AU" term="%22Larocca+A%22">Larocca A</searchLink>; Department of Molecular Biotechnology and Health Sciences, Division of Hematology University of Torino Torino Italy.<br /><searchLink fieldCode="AU" term="%22Palacios+JJL%22">Palacios JJL</searchLink>; Hospital Universitario 12 de Octubre CIBER-ONC CB16/12/00369, CNIO Madrid Spain.<br /><searchLink fieldCode="AU" term="%22Wester+R%22">Wester R</searchLink>; Department of Hematology Erasmus MC Cancer Institute Rotterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bertsch+U%22">Bertsch U</searchLink>; National Center for Tumor Diseases Heidelberg Heidelberg Germany.; Department of Medicine V, Heidelberg Myeloma Center University Hospital Heidelberg Heidelberg Germany.<br /><searchLink fieldCode="AU" term="%22Waage+A%22">Waage A</searchLink>; Institute of Clinical and Molecular Medicine Norwegian University of Science and Technology and St. Olavs Hospital Trondheim Norway.<br /><searchLink fieldCode="AU" term="%22Zamagni+E%22">Zamagni E</searchLink>; Department of Medical and Surgical Sciences, 'Seràgnoli' Institute of Hematology University of Bologna Bologna Italy.; IRCCS Azienda Ospedaliero-Universitaria di Bologna Bologna Italy.<br /><searchLink fieldCode="AU" term="%22Pérez+Míguez+C%22">Pérez Míguez C</searchLink>; Department of Hematology, IDIS University Hospital of Santiago de Compostela Santiago de Compostela Spain.<br /><searchLink fieldCode="AU" term="%22Rojas+Martínez+JA%22">Rojas Martínez JA</searchLink>; Department of Hematology, IDIS University Hospital of Santiago de Compostela Santiago de Compostela Spain.<br /><searchLink fieldCode="AU" term="%22Mai+EK%22">Mai EK</searchLink>; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, University Hospital Heidelberg GMMG Study Group Heidelberg Germany.<br /><searchLink fieldCode="AU" term="%22Crucitti+D%22">Crucitti D</searchLink>; Department of Hematology, IDIS University Hospital of Santiago de Compostela Santiago de Compostela Spain.<br /><searchLink fieldCode="AU" term="%22Salwender+H%22">Salwender H</searchLink>; Asklepios Tumorzentrum Hamburg Asklepios Hospital Hamburg Altona and St. Georg Hamburg Germany.<br /><searchLink fieldCode="AU" term="%22Dall'Olio+D%22">Dall'Olio D</searchLink>; Department of Medical and Surgical Sciences (DIMEC) University of Bologna Bologna Italy.<br /><searchLink fieldCode="AU" term="%22Castellani+G%22">Castellani G</searchLink>; Department of Medical and Surgical Sciences (DIMEC) University of Bologna Bologna Italy.<br /><searchLink fieldCode="AU" term="%22Piñeiro+Fiel+M%22">Piñeiro Fiel M</searchLink>; Department of Hematology, IDIS University Hospital of Santiago de Compostela Santiago de Compostela Spain.<br /><searchLink fieldCode="AU" term="%22Bringhen+S%22">Bringhen S</searchLink>; AOU Città della Salute e della Scienza di Torino Torino Italy.<br /><searchLink fieldCode="AU" term="%22Zweegman+S%22">Zweegman S</searchLink>; Department of Hematology, Amsterdam UMC, Cancer Center Amsterdam Vrije Universiteit Amsterdam Amsterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Cavo+M%22">Cavo M</searchLink>; IRCCS Azienda Ospedaliero-Universitaria di Bologna Institute of Hematology 'L. e A. Seràgnoli' Bologna Italy.; Department of Medical and Surgical Sciences University of Bologna Bologna Italy.<br /><searchLink fieldCode="AU" term="%22Iqbal+S%22">Iqbal S</searchLink>; Medical Information Scientific Engagement Johnson & Johnson Innovative Medicines New York New York United States.<br /><searchLink fieldCode="AU" term="%22Hernandez+Rivas+JM%22">Hernandez Rivas JM</searchLink>; Department of Medicine, Cancer Research Center (IBMCC, USAL-CSIC), Institute of Biomedical Research of Salamanca (IBSAL) University of Salamanca Salamanca Spain.<br /><searchLink fieldCode="AU" term="%22Bruno+B%22">Bruno B</searchLink>; Division of Hematology, AOU Città della Salute e della Scienza di Torino University of Torino Torino Italy.; Department of Molecular Biotechnology and Health Sciences University of Torino Torino Italy.<br /><searchLink fieldCode="AU" term="%22Cook+G%22">Cook G</searchLink>; Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research University of Leeds Leeds United Kingdom.<br /><searchLink fieldCode="AU" term="%22Kaiser+MF%22">Kaiser MF</searchLink>; Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research University of Leeds Leeds United Kingdom.; The Institute of Cancer Research and the Royal Marsden Hospital London United Kingdom.<br /><searchLink fieldCode="AU" term="%22Goldschmidt+H%22">Goldschmidt H</searchLink>; National Center for Tumor Diseases Heidelberg Heidelberg Germany.; Department of Medicine V, Heidelberg Myeloma Center University Hospital Heidelberg Heidelberg Germany.<br /><searchLink fieldCode="AU" term="%22Van+De+Donk+NWCJ%22">Van De Donk NWCJ</searchLink>; Department of Hematology, Amsterdam UMC, Cancer Center Amsterdam Vrije Universiteit Amsterdam Amsterdam The Netherlands.<br /><searchLink fieldCode="AU" term="%22Jackson+G%22">Jackson G</searchLink>; Department of Haematology Newcastle University Newcastle Upon Tyne United Kingdom.<br /><searchLink fieldCode="AU" term="%22San-Miguel+JF%22">San-Miguel JF</searchLink>; Clínica Universidad de Navarra CIMA, IDISNA, CIBERONC (CB16/12/00369) Pamplona Spain.<br /><searchLink fieldCode="AU" term="%22Boccadoro+M%22">Boccadoro M</searchLink>; European Myeloma Network (EMN) Italy.<br /><searchLink fieldCode="AU" term="%22Mateos+MV%22">Mateos MV</searchLink>; Department of Medicine, Cancer Research Center (IBMCC, USAL-CSIC), Institute of Biomedical Research of Salamanca (IBSAL) University of Salamanca Salamanca Spain.<br /><searchLink fieldCode="AU" term="%22Sonneveld+P%22">Sonneveld P</searchLink>; Department of Hematology Erasmus MC Cancer Institute Rotterdam The Netherlands.
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