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Helminthic larval stage induces cellular apoptosis via caspase 9-mediated mitochondrial dysfunction.

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Title: Helminthic larval stage induces cellular apoptosis via caspase 9-mediated mitochondrial dysfunction.
Authors: Sternkopf LE; Institute for Medical Microbiology, Immunology and Hygiene, TUM School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.; Center for Global Health, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany., Prodjinotho UF; Institute for Medical Microbiology, Immunology and Hygiene, TUM School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.; Center for Global Health, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany., Gres V; Institute for Infection Prevention and Control and Center for Chronic Immunodeficiency (CCI), Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany., Repgen N; Infection Pathogenesis, School of Life Sciences, Technical University of Munich (TUM), Freising, Germany., Steiger K; Institute of Pathology, Technical University of Munich (TUM), Munich, Germany., Schluckebier J; Institute for Medical Microbiology, Immunology and Hygiene, TUM School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.; Center for Global Health, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany., Sikasunge CS; Department of Paraclinical Studies, School of Veterinary Medicine, University of Zambia, Lusaka, Zambia., Stelzle D; Center for Global Health, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany., Makasi C; Department of Neurology, Kilimanjaro Christian Medical University College, Moshi, Tanzania.; National Institute for Medical Research, Muhimbili Research Centre, Dar es Salaam, Tanzania., Winkler AS; Center for Global Health, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.; Department of Neurology, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.; Department of Community Medicine and Global Health, Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway., Ngowi BJ; National Institute for Medical Research, Muhimbili Research Centre, Dar es Salaam, Tanzania.; Mbeya College of Health and Allied Sciences, University of Dar es Salaam, Mbeya, Tanzania., Villalobos N; Departamento de Patología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México (UNAM), Mexico City, Mexico., Ebner F; Infection Pathogenesis, School of Life Sciences, Technical University of Munich (TUM), Freising, Germany., Häcker G; Institute of Medical Microbiology and Hygiene, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Henneke P; Institute for Infection Prevention and Control and Center for Chronic Immunodeficiency (CCI), Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany., Prazeres da Costa C; Institute for Medical Microbiology, Immunology and Hygiene, TUM School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.; Center for Global Health, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.; German Center for Infection and Research (DZIF), Munich, Germany.
Source: Frontiers in immunology [Front Immunol] 2025 Sep 25; Vol. 16, pp. 1603385. Date of Electronic Publication: 2025 Sep 25 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Helminthic larval stage induces cellular apoptosis via caspase 9-mediated mitochondrial dysfunction.
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  Data: <searchLink fieldCode="AU" term="%22Sternkopf+LE%22">Sternkopf LE</searchLink>; Institute for Medical Microbiology, Immunology and Hygiene, TUM School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.; Center for Global Health, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Prodjinotho+UF%22">Prodjinotho UF</searchLink>; Institute for Medical Microbiology, Immunology and Hygiene, TUM School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.; Center for Global Health, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Gres+V%22">Gres V</searchLink>; Institute for Infection Prevention and Control and Center for Chronic Immunodeficiency (CCI), Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Repgen+N%22">Repgen N</searchLink>; Infection Pathogenesis, School of Life Sciences, Technical University of Munich (TUM), Freising, Germany.<br /><searchLink fieldCode="AU" term="%22Steiger+K%22">Steiger K</searchLink>; Institute of Pathology, Technical University of Munich (TUM), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schluckebier+J%22">Schluckebier J</searchLink>; Institute for Medical Microbiology, Immunology and Hygiene, TUM School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.; Center for Global Health, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Sikasunge+CS%22">Sikasunge CS</searchLink>; Department of Paraclinical Studies, School of Veterinary Medicine, University of Zambia, Lusaka, Zambia.<br /><searchLink fieldCode="AU" term="%22Stelzle+D%22">Stelzle D</searchLink>; Center for Global Health, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Makasi+C%22">Makasi C</searchLink>; Department of Neurology, Kilimanjaro Christian Medical University College, Moshi, Tanzania.; National Institute for Medical Research, Muhimbili Research Centre, Dar es Salaam, Tanzania.<br /><searchLink fieldCode="AU" term="%22Winkler+AS%22">Winkler AS</searchLink>; Center for Global Health, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.; Department of Neurology, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.; Department of Community Medicine and Global Health, Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Ngowi+BJ%22">Ngowi BJ</searchLink>; National Institute for Medical Research, Muhimbili Research Centre, Dar es Salaam, Tanzania.; Mbeya College of Health and Allied Sciences, University of Dar es Salaam, Mbeya, Tanzania.<br /><searchLink fieldCode="AU" term="%22Villalobos+N%22">Villalobos N</searchLink>; Departamento de Patología, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México (UNAM), Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Ebner+F%22">Ebner F</searchLink>; Infection Pathogenesis, School of Life Sciences, Technical University of Munich (TUM), Freising, Germany.<br /><searchLink fieldCode="AU" term="%22Häcker+G%22">Häcker G</searchLink>; Institute of Medical Microbiology and Hygiene, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Henneke+P%22">Henneke P</searchLink>; Institute for Infection Prevention and Control and Center for Chronic Immunodeficiency (CCI), Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Prazeres+da+Costa+C%22">Prazeres da Costa C</searchLink>; Institute for Medical Microbiology, Immunology and Hygiene, TUM School of Medicine and Health, Technical University of Munich (TUM), Munich, Germany.; Center for Global Health, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.; German Center for Infection and Research (DZIF), Munich, Germany.
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