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Genetic modulation of mitochondrial NAD+ regeneration does not prevent dopaminergic neuron dysfunction caused by mitochondrial complex I impairment.

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Title: Genetic modulation of mitochondrial NAD+ regeneration does not prevent dopaminergic neuron dysfunction caused by mitochondrial complex I impairment.
Authors: D'Alessandro KB; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Zampese E; Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Blum JLE; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Kuusik B; Section of Neurology, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States., Palmiotti A; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Davidson SM; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Reczek CR; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Surmeier DJ; Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States., Chandel NS; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.; Chan Zuckerberg Biohub, Chicago, IL, United States.
Source: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2025 Sep 25; Vol. 13, pp. 1650462. Date of Electronic Publication: 2025 Sep 25 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Genetic modulation of mitochondrial NAD+ regeneration does not prevent dopaminergic neuron dysfunction caused by mitochondrial complex I impairment.
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  Data: <searchLink fieldCode="AU" term="%22D'Alessandro+KB%22">D'Alessandro KB</searchLink>; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Zampese+E%22">Zampese E</searchLink>; Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Blum+JLE%22">Blum JLE</searchLink>; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Kuusik+B%22">Kuusik B</searchLink>; Section of Neurology, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Palmiotti+A%22">Palmiotti A</searchLink>; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Davidson+SM%22">Davidson SM</searchLink>; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Reczek+CR%22">Reczek CR</searchLink>; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Surmeier+DJ%22">Surmeier DJ</searchLink>; Department of Neuroscience, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.<br /><searchLink fieldCode="AU" term="%22Chandel+NS%22">Chandel NS</searchLink>; Department of Medicine, Division of Pulmonary and Critical Care Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.; Chan Zuckerberg Biohub, Chicago, IL, United States.
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  Data: <searchLink fieldCode="JN" term="%22101630250%22">Frontiers in cell and developmental biology</searchLink> [Front Cell Dev Biol] 2025 Sep 25; Vol. 13, pp. 1650462. <i>Date of Electronic Publication: </i>2025 Sep 25 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Media+S%2EA%22">Frontiers Media S.A </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101630250 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2296-634X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%222296634X%22">2296634X </searchLink><i>NLM ISO Abbreviation: </i>Front Cell Dev Biol <i>Subsets: </i>PubMed not MEDLINE
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