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The SGLT2 inhibitor empagliflozin promotes increased fatty acid oxidation in skeletal muscle cells.

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Title: The SGLT2 inhibitor empagliflozin promotes increased fatty acid oxidation in skeletal muscle cells.
Authors: Stevanovic S; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway., Katare PB; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway., Volledal HM; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway., Bakke HG; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway., Dolinar K; Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia., Pirkmajer S; Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia., Ouwens DM; Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Düsseldorf, Germany.; German Center for Diabetes Research (DZD), Munich, Germany.; Department of Endocrinology, Ghent University Hospital, Ghent, Belgium., Thoresen GH; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway.; Department of Pharmacology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Kase ET; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway., Rustan AC; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway. arild.rustan@farmasi.uio.no.
Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2026 Feb; Vol. 399 (3), pp. 3997-4010. Date of Electronic Publication: 2025 Oct 13.
Publication Type: Journal Article
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The SGLT2 inhibitor empagliflozin promotes increased fatty acid oxidation in skeletal muscle cells.
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  Data: <searchLink fieldCode="AU" term="%22Stevanovic+S%22">Stevanovic S</searchLink>; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Katare+PB%22">Katare PB</searchLink>; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Volledal+HM%22">Volledal HM</searchLink>; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Bakke+HG%22">Bakke HG</searchLink>; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Dolinar+K%22">Dolinar K</searchLink>; Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.<br /><searchLink fieldCode="AU" term="%22Pirkmajer+S%22">Pirkmajer S</searchLink>; Institute of Pathophysiology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.<br /><searchLink fieldCode="AU" term="%22Ouwens+DM%22">Ouwens DM</searchLink>; Institute of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Düsseldorf, Germany.; German Center for Diabetes Research (DZD), Munich, Germany.; Department of Endocrinology, Ghent University Hospital, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Thoresen+GH%22">Thoresen GH</searchLink>; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway.; Department of Pharmacology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Kase+ET%22">Kase ET</searchLink>; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Rustan+AC%22">Rustan AC</searchLink>; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Oslo, Norway. arild.rustan@farmasi.uio.no.
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  Data: <searchLink fieldCode="JN" term="%220326264%22">Naunyn-Schmiedeberg's archives of pharmacology</searchLink> [Naunyn Schmiedebergs Arch Pharmacol] 2026 Feb; Vol. 399 (3), pp. 3997-4010. <i>Date of Electronic Publication: </i>2025 Oct 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0326264 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1912 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200281298%22">00281298 </searchLink><i>NLM ISO Abbreviation: </i>Naunyn Schmiedebergs Arch Pharmacol <i>Subsets: </i>MEDLINE
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              Text: 2026 Feb
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