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Sedation vs General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke: The SEGA Randomized Clinical Trial.

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Title: Sedation vs General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke: The SEGA Randomized Clinical Trial.
Authors: Chen PR; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston., Artime CA; Department of Anesthesiology, Critical Care, and Pain Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston., Sheth SA; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston., Pedroza C; Institute for Clinical Research and Learning Health Care, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston., Ortega-Gutierrez S; Department of Neurology, Neurosurgery and Radiology, The University of Iowa Carver College of Medicine, University of Iowa Health, Iowa City., Wolfe S; Department of Neurosurgery, Wake Forest University School of Medicine, Atrium Health Wake Forest Baptist Health, Winston-Salem, North Carolina., Sitton C; Department of Radiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston., Kan P; Robert L. Moody Department of Neurosurgery, The University of Texas Medical Branch at Galveston, Galveston., Tanweer O; Department of Neurosurgery, Baylor College of Medicine, Baylor St Luke's Medical Center, Houston, Texas., Chebl A; Department of Neurosurgery, Henry Ford Medical Center, Detroit, Michigan., Schirmer CM; Department of Neurosurgery, Geisinger and Geisinger College of Health Sciences, Wilkes-Barre, Pennsylvania., Morrow JT; Rochester Regional Health Neuroscience Institute, Rochester General Hospital, Rochester, New York., Alderazi YJ; Neuroscience Service Line, Gulf Coast Division, HCA Houston Healthcare, Houston, Texas., Bohnstedt B; Department of Neurosurgery, Indiana University School of Medicine, Indiana University Health, Indianapolis., Erkmen K; Department of Neurosurgery, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania., Samaniego EA; Department of Neurology, Neurosurgery and Radiology, The University of Iowa Carver College of Medicine, University of Iowa Health, Iowa City., Garrido E; Department of Neurology, Neurosurgery and Radiology, The University of Iowa Carver College of Medicine, University of Iowa Health, Iowa City., Savitz SI; Institute for Stroke and Cerebrovascular Disease, The University of Texas Health Science Center at Houston, Houston., Engstrom A; The University of California, Irvine., Aguilar E; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston., Nguyen T; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston., Barreto AD; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston.; Institute for Clinical Research and Learning Health Care, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston.
Corporate Authors: SEGA Investigators
Source: JAMA neurology [JAMA Neurol] 2025 Dec 01; Vol. 82 (12), pp. 1265-1273.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Comparative Study
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589536 Publication Model: Print Cited Medium: Internet ISSN: 2168-6157 (Electronic) Linking ISSN: 21686149 NLM ISO Abbreviation: JAMA Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Sedation vs General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke: The SEGA Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Chen+PR%22">Chen PR</searchLink>; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston.<br /><searchLink fieldCode="AU" term="%22Artime+CA%22">Artime CA</searchLink>; Department of Anesthesiology, Critical Care, and Pain Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston.<br /><searchLink fieldCode="AU" term="%22Sheth+SA%22">Sheth SA</searchLink>; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston.<br /><searchLink fieldCode="AU" term="%22Pedroza+C%22">Pedroza C</searchLink>; Institute for Clinical Research and Learning Health Care, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston.<br /><searchLink fieldCode="AU" term="%22Ortega-Gutierrez+S%22">Ortega-Gutierrez S</searchLink>; Department of Neurology, Neurosurgery and Radiology, The University of Iowa Carver College of Medicine, University of Iowa Health, Iowa City.<br /><searchLink fieldCode="AU" term="%22Wolfe+S%22">Wolfe S</searchLink>; Department of Neurosurgery, Wake Forest University School of Medicine, Atrium Health Wake Forest Baptist Health, Winston-Salem, North Carolina.<br /><searchLink fieldCode="AU" term="%22Sitton+C%22">Sitton C</searchLink>; Department of Radiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston.<br /><searchLink fieldCode="AU" term="%22Kan+P%22">Kan P</searchLink>; Robert L. Moody Department of Neurosurgery, The University of Texas Medical Branch at Galveston, Galveston.<br /><searchLink fieldCode="AU" term="%22Tanweer+O%22">Tanweer O</searchLink>; Department of Neurosurgery, Baylor College of Medicine, Baylor St Luke's Medical Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Chebl+A%22">Chebl A</searchLink>; Department of Neurosurgery, Henry Ford Medical Center, Detroit, Michigan.<br /><searchLink fieldCode="AU" term="%22Schirmer+CM%22">Schirmer CM</searchLink>; Department of Neurosurgery, Geisinger and Geisinger College of Health Sciences, Wilkes-Barre, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Morrow+JT%22">Morrow JT</searchLink>; Rochester Regional Health Neuroscience Institute, Rochester General Hospital, Rochester, New York.<br /><searchLink fieldCode="AU" term="%22Alderazi+YJ%22">Alderazi YJ</searchLink>; Neuroscience Service Line, Gulf Coast Division, HCA Houston Healthcare, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Bohnstedt+B%22">Bohnstedt B</searchLink>; Department of Neurosurgery, Indiana University School of Medicine, Indiana University Health, Indianapolis.<br /><searchLink fieldCode="AU" term="%22Erkmen+K%22">Erkmen K</searchLink>; Department of Neurosurgery, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Samaniego+EA%22">Samaniego EA</searchLink>; Department of Neurology, Neurosurgery and Radiology, The University of Iowa Carver College of Medicine, University of Iowa Health, Iowa City.<br /><searchLink fieldCode="AU" term="%22Garrido+E%22">Garrido E</searchLink>; Department of Neurology, Neurosurgery and Radiology, The University of Iowa Carver College of Medicine, University of Iowa Health, Iowa City.<br /><searchLink fieldCode="AU" term="%22Savitz+SI%22">Savitz SI</searchLink>; Institute for Stroke and Cerebrovascular Disease, The University of Texas Health Science Center at Houston, Houston.<br /><searchLink fieldCode="AU" term="%22Engstrom+A%22">Engstrom A</searchLink>; The University of California, Irvine.<br /><searchLink fieldCode="AU" term="%22Aguilar+E%22">Aguilar E</searchLink>; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston.<br /><searchLink fieldCode="AU" term="%22Nguyen+T%22">Nguyen T</searchLink>; Department of Neurosurgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston.<br /><searchLink fieldCode="AU" term="%22Barreto+AD%22">Barreto AD</searchLink>; Department of Neurology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston.; Institute for Clinical Research and Learning Health Care, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Medical+Association%22">American Medical Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101589536 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2168-6157 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221686149%22">21686149 </searchLink><i>NLM ISO Abbreviation: </i>JAMA Neurol <i>Subsets: </i>MEDLINE
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