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Apomorphine is a novel necroptosis inhibitor targeting mixed lineage kinase domain-like protein oligomerization.

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Title: Apomorphine is a novel necroptosis inhibitor targeting mixed lineage kinase domain-like protein oligomerization.
Authors: Han M; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea.; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea., Seo DH; Ochang Center, Korea Basic Science Institute, Cheongju-Si, South Korea.; KBSI School of Bioscience, University of Science and Technology, Daejeon, South Korea., Kwak MS; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea.; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea., Park IH; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Yonsei University College of Medicine, Seoul, South Korea., Rhee WJ; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea.; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea., Kim HS; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea., Jeon E; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea., Lee JJ; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea.; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea., Park CH; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea., Kim ND; Voronoibio Inc., Yeonsu-gu, South Korea., Sim T; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Yonsei University College of Medicine, Seoul, South Korea., Kim YS; Department of Biochemistry, Ajou University School of Medicine, Yeongtong-gu, Republic of Korea.; Department of Biomedical Sciences, Graduate School of Ajou University, Yeongtong-gu, Republic of Korea., Ryu KS; Ochang Center, Korea Basic Science Institute, Cheongju-Si, South Korea. ksryu@kbsi.re.kr.; KBSI School of Bioscience, University of Science and Technology, Daejeon, South Korea. ksryu@kbsi.re.kr., Shin JS; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea. jsshin6203@yuhs.ac.; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea. jsshin6203@yuhs.ac.; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea. jsshin6203@yuhs.ac.; Center for Nanomedicine, Institute for Basic Science (IBS), Yonsei University, Seoul, South Korea. jsshin6203@yuhs.ac.
Source: Cell death discovery [Cell Death Discov] 2025 Oct 13; Vol. 11 (1), pp. 457. Date of Electronic Publication: 2025 Oct 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Apomorphine is a novel necroptosis inhibitor targeting mixed lineage kinase domain-like protein oligomerization.
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  Data: <searchLink fieldCode="AU" term="%22Han+M%22">Han M</searchLink>; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea.; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Seo+DH%22">Seo DH</searchLink>; Ochang Center, Korea Basic Science Institute, Cheongju-Si, South Korea.; KBSI School of Bioscience, University of Science and Technology, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Kwak+MS%22">Kwak MS</searchLink>; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea.; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Park+IH%22">Park IH</searchLink>; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Yonsei University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Rhee+WJ%22">Rhee WJ</searchLink>; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea.; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Kim+HS%22">Kim HS</searchLink>; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Jeon+E%22">Jeon E</searchLink>; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JJ%22">Lee JJ</searchLink>; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea.; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Park+CH%22">Park CH</searchLink>; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Kim+ND%22">Kim ND</searchLink>; Voronoibio Inc., Yeonsu-gu, South Korea.<br /><searchLink fieldCode="AU" term="%22Sim+T%22">Sim T</searchLink>; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Yonsei University College of Medicine, Seoul, South Korea.<br /><searchLink fieldCode="AU" term="%22Kim+YS%22">Kim YS</searchLink>; Department of Biochemistry, Ajou University School of Medicine, Yeongtong-gu, Republic of Korea.; Department of Biomedical Sciences, Graduate School of Ajou University, Yeongtong-gu, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Ryu+KS%22">Ryu KS</searchLink>; Ochang Center, Korea Basic Science Institute, Cheongju-Si, South Korea. ksryu@kbsi.re.kr.; KBSI School of Bioscience, University of Science and Technology, Daejeon, South Korea. ksryu@kbsi.re.kr.<br /><searchLink fieldCode="AU" term="%22Shin+JS%22">Shin JS</searchLink>; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea. jsshin6203@yuhs.ac.; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea. jsshin6203@yuhs.ac.; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea. jsshin6203@yuhs.ac.; Center for Nanomedicine, Institute for Basic Science (IBS), Yonsei University, Seoul, South Korea. jsshin6203@yuhs.ac.
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  Data: <searchLink fieldCode="JN" term="%22101665035%22">Cell death discovery</searchLink> [Cell Death Discov] 2025 Oct 13; Vol. 11 (1), pp. 457. <i>Date of Electronic Publication: </i>2025 Oct 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101665035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2058-7716 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220587716%22">20587716 </searchLink><i>NLM ISO Abbreviation: </i>Cell Death Discov <i>Subsets: </i>PubMed not MEDLINE
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