A PP2A molecular glue overcomes RAS/MAPK inhibitor resistance in KRAS-mutant non-small cell lung cancer.
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| Title: | A PP2A molecular glue overcomes RAS/MAPK inhibitor resistance in KRAS-mutant non-small cell lung cancer. |
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| Authors: | Raines B; Cellular and Molecular Biology Program and.; Department of Internal Medicine, Division of Genetic Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Health, Ann Arbor, Michigan, USA., Tseng-Rogenski S; Department of Internal Medicine, Division of Genetic Medicine, University of Michigan, Ann Arbor, Michigan, USA., Dowdican AC; Department of Internal Medicine, Division of Genetic Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Health, Ann Arbor, Michigan, USA., Peris I; Department of Internal Medicine, Division of Genetic Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Health, Ann Arbor, Michigan, USA., Hinderman M; Department of Internal Medicine, Division of Genetic Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Health, Ann Arbor, Michigan, USA., Zawacki KP; Department of Internal Medicine, Division of Genetic Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Health, Ann Arbor, Michigan, USA., Barrie K; Department of Internal Medicine, Division of Genetic Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Health, Ann Arbor, Michigan, USA., Hodges Onishi G; Department of Internal Medicine, Division of Genetic Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, USA., Dymond AM; Department of Internal Medicine, Division of Genetic Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Health, Ann Arbor, Michigan, USA., Luther TK; Department of Internal Medicine, Division of Genetic Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Health, Ann Arbor, Michigan, USA., Musser S; Department of Internal Medicine, Division of Genetic Medicine, University of Michigan, Ann Arbor, Michigan, USA., Karaj Majchrowski B; Department of Pharmacology and.; Department of Otolaryngology, University of Michigan, Ann Arbor, Michigan, USA., Brenner JC; Cellular and Molecular Biology Program and.; Rogel Cancer Center, University of Michigan Health, Ann Arbor, Michigan, USA.; Department of Pharmacology and.; Department of Otolaryngology, University of Michigan, Ann Arbor, Michigan, USA., Ahmed A; Department of Internal Medicine, Division of Genetic Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Health, Ann Arbor, Michigan, USA., Taylor DJ; Department of Pharmacology, Case Western Reserve University, Cleveland, Ohio, USA.; Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio, USA., O'Connor CM; Department of Internal Medicine, Division of Genetic Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Health, Ann Arbor, Michigan, USA., Narla G; Cellular and Molecular Biology Program and.; Department of Internal Medicine, Division of Genetic Medicine, University of Michigan, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Health, Ann Arbor, Michigan, USA. |
| Source: | The Journal of clinical investigation [J Clin Invest] 2025 Oct 14; Vol. 135 (23). Date of Electronic Publication: 2025 Oct 14 (Print Publication: 2025). |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: eCollection Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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